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Items: 1 to 20 of 197

1.

Cytotoxic effect of the pentacyclic oxindole alkaloid mitraphylline isolated from Uncaria tomentosa bark on human Ewing's sarcoma and breast cancer cell lines.

García Giménez D, García Prado E, Sáenz Rodríguez T, Fernández Arche A, De la Puerta R.

Planta Med. 2010 Feb;76(2):133-6. doi: 10.1055/s-0029-1186048. Epub 2009 Sep 1.

PMID:
19724995
2.

Antiproliferative effects of mitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on human glioma and neuroblastoma cell lines.

García Prado E, García Gimenez MD, De la Puerta Vázquez R, Espartero Sánchez JL, Sáenz Rodríguez MT.

Phytomedicine. 2007 Apr;14(4):280-4. Epub 2007 Feb 12.

PMID:
17296291
3.

Genotoxicity and cytotoxicity of oxindole alkaloids from Uncaria tomentosa (cat's claw): Chemotype relevance.

Kaiser S, Carvalho ÂR, Pittol V, Dietrich F, Manica F, Machado MM, de Oliveira LF, Oliveira Battastini AM, Ortega GG.

J Ethnopharmacol. 2016 Aug 2;189:90-8. doi: 10.1016/j.jep.2016.05.026. Epub 2016 May 13.

PMID:
27180878
4.

Cat's claw oxindole alkaloid isomerization induced by cell incubation and cytotoxic activity against T24 and RT4 human bladder cancer cell lines.

Kaiser S, Dietrich F, de Resende PE, Verza SG, Moraes RC, Morrone FB, Batastini AM, Ortega GG.

Planta Med. 2013 Oct;79(15):1413-20. doi: 10.1055/s-0033-1350742. Epub 2013 Aug 23.

PMID:
23975868
5.

The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line.

Riva L, Coradini D, Di Fronzo G, De Feo V, De Tommasi N, De Simone F, Pizza C.

Anticancer Res. 2001 Jul-Aug;21(4A):2457-61.

PMID:
11724307
6.

Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition.

Pilarski R, Filip B, Wietrzyk J, Kuraś M, Gulewicz K.

Phytomedicine. 2010 Dec 1;17(14):1133-9. doi: 10.1016/j.phymed.2010.04.013. Epub 2010 Jun 25.

PMID:
20576410
7.

Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content.

Sandoval M, Okuhama NN, Zhang XJ, Condezo LA, Lao J, Angeles' FM, Musah RA, Bobrowski P, Miller MJ.

Phytomedicine. 2002 May;9(4):325-37.

PMID:
12120814
8.

Inhibitory mechanisms of two Uncaria tomentosa extracts affecting the Wnt-signaling pathway.

Gurrola-Díaz CM, García-López PM, Gulewicz K, Pilarski R, Dihlmann S.

Phytomedicine. 2011 Jun 15;18(8-9):683-90. doi: 10.1016/j.phymed.2010.11.002. Epub 2010 Dec 14.

PMID:
21156346
9.

In vitro effects of two extracts and two pure alkaloid preparations of Uncaria tomentosa on peripheral blood mononuclear cells.

Winkler C, Wirleitner B, Schroecksnadel K, Schennach H, Mur E, Fuchs D.

Planta Med. 2004 Mar;70(3):205-10.

PMID:
15114496
10.

Uncaria tomentosa aqueous-ethanol extract triggers an immunomodulation toward a Th2 cytokine profile.

Domingues A, Sartori A, Valente LM, Golim MA, Siani AC, Viero RM.

Phytother Res. 2011 Aug;25(8):1229-35. doi: 10.1002/ptr.3549. Epub 2011 Jun 8.

PMID:
21656603
11.
12.

Effect of Alkaloid-Free and Alkaloid-Rich preparations from Uncaria tomentosa bark on mitotic activity and chromosome morphology evaluated by Allium Test.

Kuraś M, Pilarski R, Nowakowska J, Zobel A, Brzost K, Antosiewicz J, Gulewicz K.

J Ethnopharmacol. 2009 Jan 12;121(1):140-7. doi: 10.1016/j.jep.2008.10.023. Epub 2008 Nov 5.

PMID:
19027059
13.

Cytotoxic dimeric indole alkaloids from Catharanthus roseus.

Wang CH, Wang GC, Wang Y, Zhang XQ, Huang XJ, Zhang DM, Chen MF, Ye WC.

Fitoterapia. 2012 Jun;83(4):765-9. doi: 10.1016/j.fitote.2012.03.007. Epub 2012 Mar 13.

PMID:
22445552
14.

Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells.

Cheng AC, Jian CB, Huang YT, Lai CS, Hsu PC, Pan MH.

Food Chem Toxicol. 2007 Nov;45(11):2206-18. Epub 2007 Jun 7.

PMID:
17619071
15.
16.

Two new cytotoxic isomeric indole alkaloids from the roots of Nauclea orientalis.

Sichaem J, Surapinit S, Siripong P, Khumkratok S, Jong-aramruang J, Tip-pyang S.

Fitoterapia. 2010 Oct;81(7):830-3. doi: 10.1016/j.fitote.2010.05.004. Epub 2010 May 21.

PMID:
20472039
17.

Uncaria tomentosa Leaves Decoction Modulates Differently ROS Production in Cancer and Normal Cells, and Effects Cisplatin Cytotoxicity.

Kośmider A, Czepielewska E, Kuraś M, Gulewicz K, Pietrzak W, Nowak R, Nowicka G.

Molecules. 2017 Apr 12;22(4). pii: E620. doi: 10.3390/molecules22040620.

18.

Antiproliferative and pro-apoptotic effects of Uncaria tomentosa in human medullary thyroid carcinoma cells.

Rinner B, Li ZX, Haas H, Siegl V, Sturm S, Stuppner H, Pfragner R.

Anticancer Res. 2009 Nov;29(11):4519-28.

19.

Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark.

Rojas-Duran R, González-Aspajo G, Ruiz-Martel C, Bourdy G, Doroteo-Ortega VH, Alban-Castillo J, Robert G, Auberger P, Deharo E.

J Ethnopharmacol. 2012 Oct 11;143(3):801-4. doi: 10.1016/j.jep.2012.07.015. Epub 2012 Jul 27.

PMID:
22846434
20.

Cytotoxic activity of Brazilian Cerrado plants used in traditional medicine against cancer cell lines.

de Mesquita ML, de Paula JE, Pessoa C, de Moraes MO, Costa-Lotufo LV, Grougnet R, Michel S, Tillequin F, Espindola LS.

J Ethnopharmacol. 2009 Jun 25;123(3):439-45. doi: 10.1016/j.jep.2009.03.018. Epub 2009 Mar 26.

PMID:
19501276

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