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Items: 1 to 20 of 165

1.

Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis.

Guo R, Zhou Q, Proulx ST, Wood R, Ji RC, Ritchlin CT, Pytowski B, Zhu Z, Wang YJ, Schwarz EM, Xing L.

Arthritis Rheum. 2009 Sep;60(9):2666-76. doi: 10.1002/art.24764.

2.

Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice.

Zhou Q, Guo R, Wood R, Boyce BF, Liang Q, Wang YJ, Schwarz EM, Xing L.

Arthritis Rheum. 2011 Aug;63(8):2318-28. doi: 10.1002/art.30421.

3.

Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer.

Yang H, Kim C, Kim MJ, Schwendener RA, Alitalo K, Heston W, Kim I, Kim WJ, Koh GY.

Mol Cancer. 2011 Apr 11;10:36. doi: 10.1186/1476-4598-10-36.

4.

Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3.

Kodera Y, Katanasaka Y, Kitamura Y, Tsuda H, Nishio K, Tamura T, Koizumi F.

Breast Cancer Res. 2011 Jun 21;13(3):R66. doi: 10.1186/bcr2903.

5.

Increased lymphangiogenesis in joints of mice with inflammatory arthritis.

Zhang Q, Lu Y, Proulx ST, Guo R, Yao Z, Schwarz EM, Boyce BF, Xing L.

Arthritis Res Ther. 2007;9(6):R118.

6.

Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation.

Huggenberger R, Ullmann S, Proulx ST, Pytowski B, Alitalo K, Detmar M.

J Exp Med. 2010 Sep 27;207(10):2255-69. doi: 10.1084/jem.20100559. Epub 2010 Sep 13.

7.
8.

The VEGF-C/VEGFR3 signaling pathway contributes to resolving chronic skin inflammation by activating lymphatic vessel function.

Hagura A, Asai J, Maruyama K, Takenaka H, Kinoshita S, Katoh N.

J Dermatol Sci. 2014 Feb;73(2):135-41. doi: 10.1016/j.jdermsci.2013.10.006. Epub 2013 Oct 29.

PMID:
24252749
9.

Efficacy of B cell depletion therapy for murine joint arthritis flare is associated with increased lymphatic flow.

Li J, Ju Y, Bouta EM, Xing L, Wood RW, Kuzin I, Bottaro A, Ritchlin CT, Schwarz EM.

Arthritis Rheum. 2013 Jan;65(1):130-8. doi: 10.1002/art.37709.

10.

Tumor-induced lymphangiogenesis in cervical lymph nodes in oral melanoma-bearing mice.

Ozasa R, Ohno J, Iwahashi T, Taniguchi K.

J Exp Clin Cancer Res. 2012 Oct 2;31:83. doi: 10.1186/1756-9966-31-83.

11.

MRI and quantification of draining lymph node function in inflammatory arthritis.

Proulx ST, Kwok E, You Z, Beck CA, Shealy DJ, Ritchlin CT, Boyce BF, Xing L, Schwarz EM.

Ann N Y Acad Sci. 2007 Nov;1117:106-23. Epub 2007 Jul 23.

PMID:
17646265
12.

In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography.

Mumprecht V, Honer M, Vigl B, Proulx ST, Trachsel E, Kaspar M, Banziger-Tobler NE, Schibli R, Neri D, Detmar M.

Cancer Res. 2010 Nov 1;70(21):8842-51. doi: 10.1158/0008-5472.CAN-10-0896. Epub 2010 Oct 26.

13.

Brief Report: Treatment of Tumor Necrosis Factor-Transgenic Mice With Anti-Tumor Necrosis Factor Restores Lymphatic Contractions, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress.

Bouta EM, Kuzin I, de Mesy Bentley K, Wood RW, Rahimi H, Ji RC, Ritchlin CT, Bottaro A, Xing L, Schwarz EM.

Arthritis Rheumatol. 2017 Jun;69(6):1187-1193. doi: 10.1002/art.40047. Epub 2017 Apr 4.

PMID:
28118521
14.

VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes.

Halin C, Tobler NE, Vigl B, Brown LF, Detmar M.

Blood. 2007 Nov 1;110(9):3158-67. Epub 2007 Jul 11.

15.
16.

Blockade of prolymphangiogenic vascular endothelial growth factor C in dry eye disease.

Goyal S, Chauhan SK, Dana R.

Arch Ophthalmol. 2012 Jan;130(1):84-9. doi: 10.1001/archophthalmol.2011.266. Epub 2011 Sep 12.

17.

Blockade of FLT4 suppresses metastasis of melanoma cells by impaired lymphatic vessels.

Lee JY, Hong SH, Shin M, Heo HR, Jang IH.

Biochem Biophys Res Commun. 2016 Sep 16;478(2):733-8. doi: 10.1016/j.bbrc.2016.08.017. Epub 2016 Aug 6.

PMID:
27507214
18.

CD23(+)/CD21(hi) B-cell translocation and ipsilateral lymph node collapse is associated with asymmetric arthritic flare in TNF-Tg mice.

Li J, Zhou Q, Wood RW, Kuzin I, Bottaro A, Ritchlin CT, Xing L, Schwarz EM.

Arthritis Res Ther. 2011 Aug 31;13(4):R138. doi: 10.1186/ar3452.

19.

Lack of lymphatics and lymph node-mediated immunity in choroidal neovascularization.

Nakao S, Zandi S, Kohno R, Sun D, Nakama T, Ishikawa K, Yoshida S, Enaida H, Ishibashi T, Hafezi-Moghadam A.

Invest Ophthalmol Vis Sci. 2013 Jun 3;54(6):3830-6. doi: 10.1167/iovs.12-10341. Erratum in: Invest Ophthalmol Vis Sci. 2013 Jul;54(7):4451.

20.

Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody.

Pytowski B, Goldman J, Persaud K, Wu Y, Witte L, Hicklin DJ, Skobe M, Boardman KC, Swartz MA.

J Natl Cancer Inst. 2005 Jan 5;97(1):14-21.

PMID:
15632376

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