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Items: 1 to 20 of 86


From mitochondrial dynamics to arrhythmias.

Aon MA, Cortassa S, Akar FG, Brown DA, Zhou L, O'Rourke B.

Int J Biochem Cell Biol. 2009 Oct;41(10):1940-8. doi: 10.1016/j.biocel.2009.02.016. Epub 2009 Mar 5. Review.


Mitochondrial oscillations in physiology and pathophysiology.

Aon MA, Cortassa S, O'Rourke B.

Adv Exp Med Biol. 2008;641:98-117. Review.


Mitochondrial instability during regional ischemia-reperfusion underlies arrhythmias in monolayers of cardiomyocytes.

Solhjoo S, O'Rourke B.

J Mol Cell Cardiol. 2015 Jan;78:90-9. doi: 10.1016/j.yjmcc.2014.09.024. Epub 2014 Sep 28.


Cardiac mitochondria and arrhythmias.

Brown DA, O'Rourke B.

Cardiovasc Res. 2010 Nov 1;88(2):241-9. doi: 10.1093/cvr/cvq231. Epub 2010 Jul 9. Review.


Effects of regional mitochondrial depolarization on electrical propagation: implications for arrhythmogenesis.

Zhou L, Solhjoo S, Millare B, Plank G, Abraham MR, Cortassa S, Trayanova N, O'Rourke B.

Circ Arrhythm Electrophysiol. 2014 Feb;7(1):143-51. doi: 10.1161/CIRCEP.113.000600. Epub 2014 Jan 1.


Cardiac arrhythmias induced by glutathione oxidation can be inhibited by preventing mitochondrial depolarization.

Brown DA, Aon MA, Frasier CR, Sloan RC, Maloney AH, Anderson EJ, O'Rourke B.

J Mol Cell Cardiol. 2010 Apr;48(4):673-9. doi: 10.1016/j.yjmcc.2009.11.011. Epub 2009 Dec 3.


Metabolic stress, reactive oxygen species, and arrhythmia.

Jeong EM, Liu M, Sturdy M, Gao G, Varghese ST, Sovari AA, Dudley SC Jr.

J Mol Cell Cardiol. 2012 Feb;52(2):454-63. doi: 10.1016/j.yjmcc.2011.09.018. Epub 2011 Sep 25. Review.


Mitochondrial networks in cardiac myocytes reveal dynamic coupling behavior.

Kurz FT, Derungs T, Aon MA, O'Rourke B, Armoundas AA.

Biophys J. 2015 Apr 21;108(8):1922-33. doi: 10.1016/j.bpj.2015.01.040.


Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes.

Aon MA, Cortassa S, Marbán E, O'Rourke B.

J Biol Chem. 2003 Nov 7;278(45):44735-44. Epub 2003 Aug 20.


Modeling cardiac action potential shortening driven by oxidative stress-induced mitochondrial oscillations in guinea pig cardiomyocytes.

Zhou L, Cortassa S, Wei AC, Aon MA, Winslow RL, O'Rourke B.

Biophys J. 2009 Oct 7;97(7):1843-52. doi: 10.1016/j.bpj.2009.07.029.


Percolation and criticality in a mitochondrial network.

Aon MA, Cortassa S, O'Rourke B.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4447-52. Epub 2004 Mar 18.


Functional Role of Mitochondria in Arrhythmogenesis.

Gambardella J, Sorriento D, Ciccarelli M, Del Giudice C, Fiordelisi A, Napolitano L, Trimarco B, Iaccarino G, Santulli G.

Adv Exp Med Biol. 2017;982:191-202. doi: 10.1007/978-3-319-55330-6_10. Review.


Altered spatiotemporal dynamics of the mitochondrial membrane potential in the hypertrophied heart.

Jin H, Nass RD, Joudrey PJ, Lyon AR, Chemaly ER, Rapti K, Akar FG.

Biophys J. 2010 May 19;98(10):2063-71. doi: 10.1016/j.bpj.2010.01.045.


A reaction-diffusion model of ROS-induced ROS release in a mitochondrial network.

Zhou L, Aon MA, Almas T, Cortassa S, Winslow RL, O'Rourke B.

PLoS Comput Biol. 2010 Jan 29;6(1):e1000657. doi: 10.1371/journal.pcbi.1000657.


Mitochondrial criticality: a new concept at the turning point of life or death.

Aon MA, Cortassa S, Akar FG, O'Rourke B.

Biochim Biophys Acta. 2006 Feb;1762(2):232-40. Epub 2005 Sep 27. Review.


From cardiac mitochondrial dysfunction to clinical arrhythmias.

Montaigne D, Maréchal X, Lacroix D, Staels B.

Int J Cardiol. 2015 Apr 1;184:597-9. doi: 10.1016/j.ijcard.2015.03.012. Epub 2015 Mar 3. Review. No abstract available.


The mitochondrial origin of postischemic arrhythmias.

Akar FG, Aon MA, Tomaselli GF, O'Rourke B.

J Clin Invest. 2005 Dec;115(12):3527-35. Epub 2005 Nov 10.


Mitochondrial ion channels in cardiac function and dysfunction.

O'Rourke B, Cortassa S, Akar F, Aon M.

Novartis Found Symp. 2007;287:140-51; discussion 152-6. Review.


A mitochondrial oscillator dependent on reactive oxygen species.

Cortassa S, Aon MA, Winslow RL, O'Rourke B.

Biophys J. 2004 Sep;87(3):2060-73.

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