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Items: 1 to 20 of 152

1.

p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content.

Park JY, Wang PY, Matsumoto T, Sung HJ, Ma W, Choi JW, Anderson SA, Leary SC, Balaban RS, Kang JG, Hwang PM.

Circ Res. 2009 Sep 25;105(7):705-12, 11 p following 712. doi: 10.1161/CIRCRESAHA.109.205310.

2.

Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice.

Safdar A, Khrapko K, Flynn JM, Saleem A, De Lisio M, Johnston AP, Kratysberg Y, Samjoo IA, Kitaoka Y, Ogborn DI, Little JP, Raha S, Parise G, Akhtar M, Hettinga BP, Rowe GC, Arany Z, Prolla TA, Tarnopolsky MA.

Skelet Muscle. 2016 Jan 31;6:7. doi: 10.1186/s13395-016-0075-9.

3.
4.

The emerging role of p53 in exercise metabolism.

Bartlett JD, Close GL, Drust B, Morton JP.

Sports Med. 2014 Mar;44(3):303-9. doi: 10.1007/s40279-013-0127-9. Review.

PMID:
24264057
5.

Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle.

Konokhova Y, Spendiff S, Jagoe RT, Aare S, Kapchinsky S, MacMillan NJ, Rozakis P, Picard M, Aubertin-Leheudre M, Pion CH, Bourbeau J, Hepple RT, Taivassalo T.

Skelet Muscle. 2016 Feb 18;6:10. doi: 10.1186/s13395-016-0083-9.

6.

MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j3.

Yamamoto H, Morino K, Nishio Y, Ugi S, Yoshizaki T, Kashiwagi A, Maegawa H.

Am J Physiol Endocrinol Metab. 2012 Dec 15;303(12):E1419-27. doi: 10.1152/ajpendo.00097.2012.

7.

The regulation of mitochondrial transcription factor A (Tfam) expression during skeletal muscle cell differentiation.

Collu-Marchese M, Shuen M, Pauly M, Saleem A, Hood DA.

Biosci Rep. 2015 May 19;35(3). pii: e00221. doi: 10.1042/BSR20150073.

8.

Exercise training attenuates oxidative stress and decreases p53 protein content in skeletal muscle of type 2 diabetic Goto-Kakizaki rats.

Qi Z, He J, Zhang Y, Shao Y, Ding S.

Free Radic Biol Med. 2011 Apr 1;50(7):794-800. doi: 10.1016/j.freeradbiomed.2010.12.022.

PMID:
21185935
9.

Inhibitory effect of p53 on mitochondrial content and function during adipogenesis.

Okita N, Ishikawa N, Mizunoe Y, Oku M, Nagai W, Suzuki Y, Matsushima S, Mikami K, Okado H, Sasaki T, Higami Y.

Biochem Biophys Res Commun. 2014 Mar 28;446(1):91-7. doi: 10.1016/j.bbrc.2014.02.059.

PMID:
24565844
10.

Impact of endurance training on murine spontaneous activity, muscle mitochondrial DNA abundance, gene transcripts, and function.

Chow LS, Greenlund LJ, Asmann YW, Short KR, McCrady SK, Levine JA, Nair KS.

J Appl Physiol (1985). 2007 Mar;102(3):1078-89.

11.

Endurance training ameliorates the metabolic and performance characteristics of circadian Clock mutant mice.

Pastore S, Hood DA.

J Appl Physiol (1985). 2013 Apr;114(8):1076-84. doi: 10.1152/japplphysiol.01505.2012.

12.

Compensatory responses of protein import and transcription factor expression in mitochondrial DNA defects.

Joseph AM, Rungi AA, Robinson BH, Hood DA.

Am J Physiol Cell Physiol. 2004 Apr;286(4):C867-75.

13.

Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance.

Davis JM, Murphy EA, Carmichael MD, Davis B.

Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7. doi: 10.1152/ajpregu.90925.2008.

14.

Training intensity modulates changes in PGC-1α and p53 protein content and mitochondrial respiration, but not markers of mitochondrial content in human skeletal muscle.

Granata C, Oliveira RS, Little JP, Renner K, Bishop DJ.

FASEB J. 2016 Feb;30(2):959-70. doi: 10.1096/fj.15-276907.

PMID:
26572168
15.

Mitochondrial uncoupling reduces exercise capacity despite several skeletal muscle metabolic adaptations.

Schlagowski AI, Singh F, Charles AL, Gali Ramamoorthy T, Favret F, Piquard F, Geny B, Zoll J.

J Appl Physiol (1985). 2014 Feb 15;116(4):364-75. doi: 10.1152/japplphysiol.01177.2013.

16.

Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity.

Lustgarten MS, Jang YC, Liu Y, Muller FL, Qi W, Steinhelper M, Brooks SV, Larkin L, Shimizu T, Shirasawa T, McManus LM, Bhattacharya A, Richardson A, Van Remmen H.

Am J Physiol Cell Physiol. 2009 Dec;297(6):C1520-32. doi: 10.1152/ajpcell.00372.2009.

17.

Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content.

Toledo FG, Menshikova EV, Azuma K, Radiková Z, Kelley CA, Ritov VB, Kelley DE.

Diabetes. 2008 Apr;57(4):987-94. doi: 10.2337/db07-1429.

18.

Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3β and p53 in response to tumor necrosis factor α.

Vadrot N, Ghanem S, Braut F, Gavrilescu L, Pilard N, Mansouri A, Moreau R, Reyl-Desmars F.

PLoS One. 2012;7(7):e40879. doi: 10.1371/journal.pone.0040879.

19.
20.

High mitochondrial DNA copy number has detrimental effects in mice.

Ylikallio E, Tyynismaa H, Tsutsui H, Ide T, Suomalainen A.

Hum Mol Genet. 2010 Jul 1;19(13):2695-705. doi: 10.1093/hmg/ddq163.

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