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Items: 1 to 20 of 242

1.

Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species.

Melillo AA, Mahawar M, Sellati TJ, Malik M, Metzger DW, Melendez JA, Bakshi CS.

J Bacteriol. 2009 Oct;191(20):6447-56. doi: 10.1128/JB.00534-09. Epub 2009 Aug 14.

2.

Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence.

Bakshi CS, Malik M, Regan K, Melendez JA, Metzger DW, Pavlov VM, Sellati TJ.

J Bacteriol. 2006 Sep;188(17):6443-8.

3.

EmrA1 membrane fusion protein of Francisella tularensis LVS is required for resistance to oxidative stress, intramacrophage survival and virulence in mice.

Ma Z, Banik S, Rane H, Mora VT, Rabadi SM, Doyle CR, Thanassi DG, Bakshi CS, Malik M.

Mol Microbiol. 2014 Mar;91(5):976-95. doi: 10.1111/mmi.12509. Epub 2014 Feb 8.

4.

An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain.

Bakshi CS, Malik M, Mahawar M, Kirimanjeswara GS, Hazlett KR, Palmer LE, Furie MB, Singh R, Melendez JA, Sellati TJ, Metzger DW.

Vaccine. 2008 Sep 26;26(41):5276-88. doi: 10.1016/j.vaccine.2008.07.051. Epub 2008 Aug 8.

5.

The contribution of reactive nitrogen and oxygen species to the killing of Francisella tularensis LVS by murine macrophages.

Lindgren H, Stenman L, Tärnvik A, Sjöstedt A.

Microbes Infect. 2005 Mar;7(3):467-75. Epub 2005 Feb 26.

PMID:
15788155
6.

Kdo hydrolase is required for Francisella tularensis virulence and evasion of TLR2-mediated innate immunity.

Okan NA, Chalabaev S, Kim TH, Fink A, Ross RA, Kasper DL.

MBio. 2013 Feb 12;4(1):e00638-12. doi: 10.1128/mBio.00638-12.

7.

Resistance of Francisella tularensis strains against reactive nitrogen and oxygen species with special reference to the role of KatG.

Lindgren H, Shen H, Zingmark C, Golovliov I, Conlan W, Sjöstedt A.

Infect Immun. 2007 Mar;75(3):1303-9. Epub 2007 Jan 8.

8.

Roles of reactive oxygen species-degrading enzymes of Francisella tularensis SCHU S4.

Binesse J, Lindgren H, Lindgren L, Conlan W, Sjöstedt A.

Infect Immun. 2015 Jun;83(6):2255-63. doi: 10.1128/IAI.02488-14. Epub 2015 Mar 23.

10.

Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain.

Pechous R, Celli J, Penoske R, Hayes SF, Frank DW, Zahrt TC.

Infect Immun. 2006 Aug;74(8):4452-61.

11.

Contribution of citrulline ureidase to Francisella tularensis strain Schu S4 pathogenesis.

Mahawar M, Kirimanjeswara GS, Metzger DW, Bakshi CS.

J Bacteriol. 2009 Aug;191(15):4798-806. doi: 10.1128/JB.00212-09. Epub 2009 Jun 5.

12.
13.

Elucidation of a mechanism of oxidative stress regulation in Francisella tularensis live vaccine strain.

Ma Z, Russo VC, Rabadi SM, Jen Y, Catlett SV, Bakshi CS, Malik M.

Mol Microbiol. 2016 Sep;101(5):856-78. doi: 10.1111/mmi.13426. Epub 2016 Jun 16.

14.

Perforin- and granzyme-mediated cytotoxic effector functions are essential for protection against Francisella tularensis following vaccination by the defined F. tularensis subsp. novicida ΔfopC vaccine strain.

Sanapala S, Yu JJ, Murthy AK, Li W, Guentzel MN, Chambers JP, Klose KE, Arulanandam BP.

Infect Immun. 2012 Jun;80(6):2177-85. doi: 10.1128/IAI.00036-12. Epub 2012 Apr 9.

15.

Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation.

Ulland TK, Janowski AM, Buchan BW, Faron M, Cassel SL, Jones BD, Sutterwala FS.

Infect Immun. 2013 Jan;81(1):201-8. doi: 10.1128/IAI.00991-12. Epub 2012 Oct 31.

16.

Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response.

Barrigan LM, Tuladhar S, Brunton JC, Woolard MD, Chen CJ, Saini D, Frothingham R, Sempowski GD, Kawula TH, Frelinger JA.

Infect Immun. 2013 Jun;81(6):2028-42. doi: 10.1128/IAI.00207-13. Epub 2013 Mar 25.

17.

Impact of Francisella tularensis pilin homologs on pilus formation and virulence.

Ark NM, Mann BJ.

Microb Pathog. 2011 Sep;51(3):110-20. doi: 10.1016/j.micpath.2011.05.001. Epub 2011 May 13.

18.

A Francisella tularensis locus required for spermine responsiveness is necessary for virulence.

Russo BC, Horzempa J, O'Dee DM, Schmitt DM, Brown MJ, Carlson PE Jr, Xavier RJ, Nau GJ.

Infect Immun. 2011 Sep;79(9):3665-76. doi: 10.1128/IAI.00135-11. Epub 2011 Jun 13.

19.

TolC-dependent modulation of host cell death by the Francisella tularensis live vaccine strain.

Doyle CR, Pan JA, Mena P, Zong WX, Thanassi DG.

Infect Immun. 2014 May;82(5):2068-78. doi: 10.1128/IAI.00044-14. Epub 2014 Mar 10.

20.

A defined O-antigen polysaccharide mutant of Francisella tularensis live vaccine strain has attenuated virulence while retaining its protective capacity.

Sebastian S, Dillon ST, Lynch JG, Blalock LT, Balon E, Lee KT, Comstock LE, Conlan JW, Rubin EJ, Tzianabos AO, Kasper DL.

Infect Immun. 2007 May;75(5):2591-602. Epub 2007 Feb 12.

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