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Items: 1 to 20 of 137

1.

Plasma amyloid-beta peptide levels correlate with adipocyte amyloid precursor protein gene expression in obese individuals.

Lee YH, Martin JM, Maple RL, Tharp WG, Pratley RE.

Neuroendocrinology. 2009;90(4):383-90. doi: 10.1159/000235555. Epub 2009 Aug 12.

PMID:
19672057
2.

Amyloid precursor protein expression is upregulated in adipocytes in obesity.

Lee YH, Tharp WG, Maple RL, Nair S, Permana PA, Pratley RE.

Obesity (Silver Spring). 2008 Jul;16(7):1493-500. doi: 10.1038/oby.2008.267. Epub 2008 May 15.

3.

Increased amyloid beta protein levels in children and adolescents with Down syndrome.

Mehta PD, Capone G, Jewell A, Freedland RL.

J Neurol Sci. 2007 Mar 15;254(1-2):22-7. Epub 2007 Feb 2.

PMID:
17275850
5.
6.

Expression of APP pathway mRNAs and proteins in Alzheimer's disease.

Matsui T, Ingelsson M, Fukumoto H, Ramasamy K, Kowa H, Frosch MP, Irizarry MC, Hyman BT.

Brain Res. 2007 Aug 3;1161:116-23. Epub 2007 Jun 5.

PMID:
17586478
7.

Plasma PTX3 protein levels inversely correlate with insulin secretion and obesity, whereas visceral adipose tissue PTX3 gene expression is increased in obesity.

Osorio-Conles O, Guitart M, Chacón MR, Maymo-Masip E, Moreno-Navarrete JM, Montori-Grau M, Näf S, Fernandez-Real JM, Vendrell J, Gómez-Foix AM.

Am J Physiol Endocrinol Metab. 2011 Dec;301(6):E1254-61. doi: 10.1152/ajpendo.00163.2011. Epub 2011 Sep 6.

8.

Caspase inhibition therapy abolishes brain trauma-induced increases in Abeta peptide: implications for clinical outcome.

Abrahamson EE, Ikonomovic MD, Ciallella JR, Hope CE, Paljug WR, Isanski BA, Flood DG, Clark RS, DeKosky ST.

Exp Neurol. 2006 Feb;197(2):437-50. Epub 2005 Nov 21.

PMID:
16300758
9.

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.

Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.

Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17967-72. Epub 2006 Nov 10.

10.

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.

Biochemistry. 1998 Nov 24;37(47):16465-71.

PMID:
9843412
11.

Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Abeta42 reduces their differentiation potential.

Uhrig M, Brechlin P, Jahn O, Knyazev Y, Weninger A, Busia L, Honarnejad K, Otto M, Hartmann T.

BMC Med. 2008 Dec 16;6:38. doi: 10.1186/1741-7015-6-38.

12.

P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.

Meredith JE Jr, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D, Fiedler T, Lentz KA, Grace JE Jr, Kolb J, Corsa J, Pierdomenico M, Jones K, Olson RE, Macor JE, Albright CF.

J Pharmacol Exp Ther. 2008 Aug;326(2):502-13. doi: 10.1124/jpet.108.138974. Epub 2008 May 22.

15.

GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.

Tian J, Shi J, Zhang L, Yin J, Hu Q, Xu Y, Sheng S, Wang P, Ren Y, Wang R, Wang Y.

Curr Alzheimer Res. 2009 Apr;6(2):118-31.

PMID:
19355846
16.

Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.

Wang PL, Niidome T, Akaike A, Kihara T, Sugimoto H.

J Neurosci Res. 2009 Jul;87(9):2105-14. doi: 10.1002/jnr.22039.

PMID:
19267423
17.
18.

Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease.

Graff-Radford NR, Crook JE, Lucas J, Boeve BF, Knopman DS, Ivnik RJ, Smith GE, Younkin LH, Petersen RC, Younkin SG.

Arch Neurol. 2007 Mar;64(3):354-62. Erratum in: Arch Neurol. 2007 Sep;64(9):1246.

PMID:
17353377
19.

Plasma visfatin concentrations and fat depot-specific mRNA expression in humans.

Berndt J, Klöting N, Kralisch S, Kovacs P, Fasshauer M, Schön MR, Stumvoll M, Blüher M.

Diabetes. 2005 Oct;54(10):2911-6.

20.

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.

Dutescu RM, Li QX, Crowston J, Masters CL, Baird PN, Culvenor JG.

Graefes Arch Clin Exp Ophthalmol. 2009 Sep;247(9):1213-21. doi: 10.1007/s00417-009-1060-3. Epub 2009 Mar 7.

PMID:
19271231

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