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Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14.

Depetris RS, Wu J, Hubbard SR.

Nat Struct Mol Biol. 2009 Aug;16(8):833-9. doi: 10.1038/nsmb.1642. Epub 2009 Aug 2. Erratum in: Nat Struct Mol Biol. 2009 Dec;16(12):1331.


Grb-ing hold of insulin signaling.

Ceccarelli DF, Sicheri F.

Nat Struct Mol Biol. 2009 Aug;16(8):803-4. doi: 10.1038/nsmb0809-803. No abstract available.


Structural basis for the interaction of the adaptor protein grb14 with activated ras.

Qamra R, Hubbard SR.

PLoS One. 2013 Aug 13;8(8):e72473. doi: 10.1371/journal.pone.0072473. eCollection 2013 Aug 13.


Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14.

Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR.

Mol Cell. 2005 Oct 28;20(2):325-33.


Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity.

Stein EG, Ghirlando R, Hubbard SR.

J Biol Chem. 2003 Apr 11;278(15):13257-64. Epub 2003 Jan 27.


Regulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins.

Desbuquois B, Carré N, Burnol AF.

FEBS J. 2013 Feb;280(3):794-816. doi: 10.1111/febs.12080. Epub 2013 Jan 2. Review.


Grb10 exceeding the boundaries of a common signaling adapter.

Riedel H.

Front Biosci. 2004 Jan 1;9:603-18. Review.


Conservation and divergence of Grb7 family of Ras-binding domains.

Rajala RV, Rajala A, Gupta VK.

Protein Cell. 2012 Jan;3(1):60-70. doi: 10.1007/s13238-012-2001-1. Epub 2012 Jan 16.


Grb10 is a dual regulator of receptor tyrosine kinase signaling.

Kabir NN, Kazi JU.

Mol Biol Rep. 2014;41(4):1985-92. doi: 10.1007/s11033-014-3046-4. Epub 2014 Jan 14. Review.


Association of Grb7 with phosphoinositides and its role in the regulation of cell migration.

Shen TL, Han DC, Guan JL.

J Biol Chem. 2002 Aug 9;277(32):29069-77. Epub 2002 May 20.


Grb10 and Grb14: enigmatic regulators of insulin action--and more?

Holt LJ, Siddle K.

Biochem J. 2005 Jun 1;388(Pt 2):393-406. Review.


Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation.

Siamakpour-Reihani S, Peterson TA, Bradford AM, Argiros HJ, Haas LL, Lor SN, Haulsee ZM, Spuches AM, Johnson DL, Rohrschneider LR, Shuster CB, Lyons BA.

J Mol Recognit. 2011 Mar-Apr;24(2):314-21. doi: 10.1002/jmr.1062.


The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors.

Stein EG, Gustafson TA, Hubbard SR.

FEBS Lett. 2001 Mar 30;493(2-3):106-11.


Lipid-protein interactions of growth factor receptor-bound protein 14 in insulin receptor signaling.

Rajala RV, Chan MD, Rajala A.

Biochemistry. 2005 Nov 29;44(47):15461-71.


Interaction of the non-phosphorylated peptide G7-18NATE with Grb7-SH2 domain requires phosphate for enhanced affinity and specificity.

Gunzburg MJ, Ambaye ND, Del Borgo MP, Pero SC, Krag DN, Wilce MC, Wilce JA.

J Mol Recognit. 2012 Jan;25(1):57-67. doi: 10.1002/jmr.2148.


Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.

Béréziat V, Kasus-Jacobi A, Perdereau D, Cariou B, Girard J, Burnol AF.

J Biol Chem. 2002 Feb 15;277(7):4845-52. Epub 2001 Nov 28.


Inhibition of FGF receptor signalling in Xenopus oocytes: differential effect of Grb7, Grb10 and Grb14.

Cailliau K, Le Marcis V, Béréziat V, Perdereau D, Cariou B, Vilain JP, Burnol AF, Browaeys-Poly E.

FEBS Lett. 2003 Jul 31;548(1-3):43-8.


Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains.

Frantz JD, Giorgetti-Peraldi S, Ottinger EA, Shoelson SE.

J Biol Chem. 1997 Jan 31;272(5):2659-67.

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