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Items: 1 to 20 of 147

1.

Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb.

Matsumoto K, Li Y, Jakuba C, Sugiyama Y, Sayo T, Okuno M, Dealy CN, Toole BP, Takeda J, Yamaguchi Y, Kosher RA.

Development. 2009 Aug;136(16):2825-35. doi: 10.1242/dev.038505.

2.

Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning.

Liu J, Li Q, Kuehn MR, Litingtung Y, Vokes SA, Chiang C.

Dev Biol. 2013 Mar 15;375(2):160-71. doi: 10.1016/j.ydbio.2012.12.018. Epub 2013 Jan 8.

3.

Hyaluronan in limb morphogenesis.

Li Y, Toole BP, Dealy CN, Kosher RA.

Dev Biol. 2007 May 15;305(2):411-20. Epub 2007 Feb 24.

4.

The role of hyaluronan produced by Has2 gene expression in development of the spine.

Roughley PJ, Lamplugh L, Lee ER, Matsumoto K, Yamaguchi Y.

Spine (Phila Pa 1976). 2011 Jun 15;36(14):E914-20. doi: 10.1097/BRS.0b013e3181f1e84f.

PMID:
21224752
5.

The metabolism of hyaluronan in cultured rabbit growth plate chondrocytes during differentiation.

Suzuki A, Tanimoto K, Ohno S, Nakatani Y, Honda K, Tanaka N, Doi T, Ohno-Nakahara M, Yoneno K, Ueki M, Tanne K.

Biochim Biophys Acta. 2005 Mar 22;1743(1-2):57-63.

6.

Aggrecan is required for growth plate cytoarchitecture and differentiation.

Lauing KL, Cortes M, Domowicz MS, Henry JG, Baria AT, Schwartz NB.

Dev Biol. 2014 Dec 15;396(2):224-36. doi: 10.1016/j.ydbio.2014.10.005. Epub 2014 Oct 18.

7.

Studies on the role of Dlx5 in regulation of chondrocyte differentiation during endochondral ossification in the developing mouse limb.

Chin HJ, Fisher MC, Li Y, Ferrari D, Wang CK, Lichtler AC, Dealy CN, Kosher RA.

Dev Growth Differ. 2007 Aug;49(6):515-21. Epub 2007 Jun 7.

PMID:
17555518
8.

Hyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone development.

Moffatt P, Lee ER, St-Jacques B, Matsumoto K, Yamaguchi Y, Roughley PJ.

Dev Dyn. 2011 Feb;240(2):404-12. doi: 10.1002/dvdy.22529. Epub 2011 Jan 3.

9.

CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention.

Huang Y, Askew EB, Knudson CB, Knudson W.

Matrix Biol. 2016 Dec;56:74-94. doi: 10.1016/j.matbio.2016.04.002. Epub 2016 Apr 14.

10.
11.

Forced chondrocyte expression of sonic hedgehog impairs joint formation affecting proliferation and apoptosis.

Tavella S, Biticchi R, Morello R, Castagnola P, Musante V, Costa D, Cancedda R, Garofalo S.

Matrix Biol. 2006 Sep;25(7):389-97. Epub 2006 Jul 29.

PMID:
16962305
12.

Fibroblast growth factor signaling regulates Dach1 expression during skeletal development.

Horner A, Shum L, Ayres JA, Nonaka K, Nuckolls GH.

Dev Dyn. 2002 Sep;225(1):35-45.

13.

Expression and activity of Runx2 mediated by hyaluronan during chondrocyte differentiation.

Tanne Y, Tanimoto K, Tanaka N, Ueki M, Lin YY, Ohkuma S, Kamiya T, Tanaka E, Tanne K.

Arch Oral Biol. 2008 May;53(5):478-87. doi: 10.1016/j.archoralbio.2007.12.007. Epub 2008 Feb 1.

PMID:
18242579
14.

ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development.

Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ.

J Bone Miner Res. 2003 Sep;18(9):1593-604.

15.

Hyaluronan synthesis and degradation in cartilage and bone.

Bastow ER, Byers S, Golub SB, Clarkin CE, Pitsillides AA, Fosang AJ.

Cell Mol Life Sci. 2008 Feb;65(3):395-413. Review.

PMID:
17965830
16.

The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development.

Probst S, Zeller R, Zuniga A.

Differentiation. 2013 Apr-Jun;85(4-5):121-30. doi: 10.1016/j.diff.2013.03.002. Epub 2013 Jun 19.

PMID:
23792766
17.

Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling.

Koyama E, Ochiai T, Rountree RB, Kingsley DM, Enomoto-Iwamoto M, Iwamoto M, Pacifici M.

Ann N Y Acad Sci. 2007 Nov;1116:100-12.

18.

FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.

Hung IH, Yu K, Lavine KJ, Ornitz DM.

Dev Biol. 2007 Jul 15;307(2):300-13. Epub 2007 May 6.

19.

Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme.

Camenisch TD, Spicer AP, Brehm-Gibson T, Biesterfeldt J, Augustine ML, Calabro A Jr, Kubalak S, Klewer SE, McDonald JA.

J Clin Invest. 2000 Aug;106(3):349-60.

20.

VEGFA is necessary for chondrocyte survival during bone development.

Zelzer E, Mamluk R, Ferrara N, Johnson RS, Schipani E, Olsen BR.

Development. 2004 May;131(9):2161-71. Epub 2004 Apr 8.

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