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Items: 1 to 20 of 110

1.

Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension.

Ogawa A, Firth AL, Yao W, Madani MM, Kerr KM, Auger WR, Jamieson SW, Thistlethwaite PA, Yuan JX.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L666-76. doi: 10.1152/ajplung.90548.2008. Epub 2009 Jul 24.

2.

PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.

Ogawa A, Firth AL, Smith KA, Maliakal MV, Yuan JX.

Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C405-11. doi: 10.1152/ajpcell.00337.2011. Epub 2011 Oct 26.

3.

PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression.

Yu Y, Sweeney M, Zhang S, Platoshyn O, Landsberg J, Rothman A, Yuan JX.

Am J Physiol Cell Physiol. 2003 Feb;284(2):C316-30.

PMID:
12529250
4.

Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.

Fernandez RA, Wan J, Song S, Smith KA, Gu Y, Tauseef M, Tang H, Makino A, Mehta D, Yuan JX.

Am J Physiol Cell Physiol. 2015 Apr 15;308(8):C581-93. doi: 10.1152/ajpcell.00202.2014. Epub 2015 Feb 11.

5.
6.

Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension.

Yao W, Firth AL, Sacks RS, Ogawa A, Auger WR, Fedullo PF, Madani MM, Lin GY, Sakakibara N, Thistlethwaite PA, Jamieson SW, Rubin LJ, Yuan JX.

Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L870-8. doi: 10.1152/ajplung.90413.2008. Epub 2009 Mar 13.

7.

Characterization of proximal pulmonary arterial cells from chronic thromboembolic pulmonary hypertension patients.

Quarck R, Wynants M, Ronisz A, Sepulveda MR, Wuytack F, Van Raemdonck D, Meyns B, Delcroix M.

Respir Res. 2012 Mar 27;13:27. doi: 10.1186/1465-9921-13-27.

8.

Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin.

Visner GA, Lu F, Zhou H, Liu J, Kazemfar K, Agarwal A.

Circulation. 2003 Feb 18;107(6):911-6.

9.

Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension.

Perros F, Montani D, Dorfmüller P, Durand-Gasselin I, Tcherakian C, Le Pavec J, Mazmanian M, Fadel E, Mussot S, Mercier O, Hervé P, Emilie D, Eddahibi S, Simonneau G, Souza R, Humbert M.

Am J Respir Crit Care Med. 2008 Jul 1;178(1):81-8. doi: 10.1164/rccm.200707-1037OC. Epub 2008 Apr 17.

PMID:
18420966
10.

Thrombin-mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension.

Ogawa A, Firth AL, Ariyasu S, Yamadori I, Matsubara H, Song S, Fraidenburg DR, Yuan JX.

Physiol Rep. 2013 Dec 29;1(7):e00190. doi: 10.1002/phy2.190. eCollection 2013 Dec 1.

11.

Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells.

Yamamura H, Yamamura A, Ko EA, Pohl NM, Smith KA, Zeifman A, Powell FL, Thistlethwaite PA, Yuan JX.

Am J Physiol Cell Physiol. 2014 May 1;306(9):C871-8. doi: 10.1152/ajpcell.00221.2013. Epub 2014 Feb 26.

12.

Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension.

Goncharov DA, Kudryashova TV, Ziai H, Ihida-Stansbury K, DeLisser H, Krymskaya VP, Tuder RM, Kawut SM, Goncharova EA.

Circulation. 2014 Feb 25;129(8):864-74. doi: 10.1161/CIRCULATIONAHA.113.004581. Epub 2013 Nov 22.

13.

Role of Na+/Ca2+ exchange in regulating cytosolic Ca2+ in cultured human pulmonary artery smooth muscle cells.

Zhang S, Yuan JX, Barrett KE, Dong H.

Am J Physiol Cell Physiol. 2005 Feb;288(2):C245-52. Epub 2004 Sep 29.

PMID:
15456699
14.
15.

Bone morphogenetic protein 4 enhances canonical transient receptor potential expression, store-operated Ca2+ entry, and basal [Ca2+]i in rat distal pulmonary arterial smooth muscle cells.

Lu W, Ran P, Zhang D, Lai N, Zhong N, Wang J.

Am J Physiol Cell Physiol. 2010 Dec;299(6):C1370-8. doi: 10.1152/ajpcell.00040.2010. Epub 2010 Sep 15.

16.
17.

A Critical Role of the mTOR/eIF2α Pathway in Hypoxia-Induced Pulmonary Hypertension.

Wang AP, Li XH, Yang YM, Li WQ, Zhang W, Hu CP, Zhang Z, Li YJ.

PLoS One. 2015 Jun 29;10(6):e0130806. doi: 10.1371/journal.pone.0130806. eCollection 2015.

18.
19.

Impaired NO-dependent inhibition of store- and receptor-operated calcium entry in pulmonary vascular smooth muscle after chronic hypoxia.

Jernigan NL, Broughton BR, Walker BR, Resta TC.

Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L517-25. Epub 2005 Oct 21.

PMID:
16243900
20.

Inhibition of endogenous TRP1 decreases capacitative Ca2+ entry and attenuates pulmonary artery smooth muscle cell proliferation.

Sweeney M, Yu Y, Platoshyn O, Zhang S, McDaniel SS, Yuan JX.

Am J Physiol Lung Cell Mol Physiol. 2002 Jul;283(1):L144-55.

PMID:
12060571

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