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Items: 1 to 20 of 134

1.

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis.

Jaiswal S, Jamieson CH, Pang WW, Park CY, Chao MP, Majeti R, Traver D, van Rooijen N, Weissman IL.

Cell. 2009 Jul 23;138(2):271-85. doi: 10.1016/j.cell.2009.05.046.

2.

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.

Theocharides AP, Jin L, Cheng PY, Prasolava TK, Malko AV, Ho JM, Poeppl AG, van Rooijen N, Minden MD, Danska JS, Dick JE, Wang JC.

J Exp Med. 2012 Sep 24;209(10):1883-99. Epub 2012 Sep 3.

3.

Transgenic expression of human CD47 markedly increases engraftment in a murine model of pig-to-human hematopoietic cell transplantation.

Tena A, Kurtz J, Leonard DA, Dobrinsky JR, Terlouw SL, Mtango N, Verstegen J, Germana S, Mallard C, Arn JS, Sachs DH, Hawley RJ.

Am J Transplant. 2014 Dec;14(12):2713-22. doi: 10.1111/ajt.12918. Epub 2014 Oct 2. Erratum in: Am J Transplant. 2015 Jan;15(1):289.

4.

A new therapeutic target for leukemia comes to the surface.

Ritchie DS, Smyth MJ.

Cell. 2009 Jul 23;138(2):226-8. doi: 10.1016/j.cell.2009.07.005.

5.

Macrophages as mediators of tumor immunosurveillance.

Jaiswal S, Chao MP, Majeti R, Weissman IL.

Trends Immunol. 2010 Jun;31(6):212-9. doi: 10.1016/j.it.2010.04.001. Epub 2010 May 7. Review.

6.

Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages.

Lv Z, Bian Z, Shi L, Niu S, Ha B, Tremblay A, Li L, Zhang X, Paluszynski J, Liu M, Zen K, Liu Y.

J Immunol. 2015 Jul 15;195(2):661-71. doi: 10.4049/jimmunol.1401719. Epub 2015 Jun 17.

7.

Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels.

Tsai RK, Rodriguez PL, Discher DE.

Blood Cells Mol Dis. 2010 Jun 15;45(1):67-74. doi: 10.1016/j.bcmd.2010.02.016. Epub 2010 Mar 17.

8.

The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.

Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I, Itoh K, Kishimoto J, Kohda D, Matozaki T, Akashi K.

Exp Hematol. 2014 Mar;42(3):163-171.e1. doi: 10.1016/j.exphem.2013.11.005. Epub 2013 Nov 20.

PMID:
24269920
9.

Soluble extracellular domains of human SIRPα and CD47 expressed in Escherichia coli enhances the phagocytosis of leukemia cells by macrophages in vitro.

Lin Y, Yan XQ, Yang F, Yang XW, Jiang X, Zhao XC, Zhu BK, Liu L, Qin HY, Liang YM, Han H.

Protein Expr Purif. 2012 Sep;85(1):109-16. doi: 10.1016/j.pep.2012.07.002. Epub 2012 Jul 17.

PMID:
22813925
10.

[CD47 and leukemia stem cells].

Cheng QS, Wang XB.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Aug;18(4):1088-91. Review. Chinese.

PMID:
20723335
11.

SIRPα-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells.

Ponce LP, Fenn NC, Moritz N, Krupka C, Kozik JH, Lauber K, Subklewe M, Hopfner KP.

Oncotarget. 2017 Feb 14;8(7):11284-11301. doi: 10.18632/oncotarget.14500.

12.

SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.

Chen J, Zhong MC, Guo H, Davidson D, Mishel S, Lu Y, Rhee I, Pérez-Quintero LA, Zhang S, Cruz-Munoz ME, Wu N, Vinh DC, Sinha M, Calderon V, Lowell CA, Danska JS, Veillette A.

Nature. 2017 Apr 27;544(7651):493-497. doi: 10.1038/nature22076. Epub 2017 Apr 19.

13.

Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.

Wang H, VerHalen J, Madariaga ML, Xiang S, Wang S, Lan P, Oldenborg PA, Sykes M, Yang YG.

Blood. 2007 Jan 15;109(2):836-42. Epub 2006 Sep 28.

14.

Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.

Teraoka Y, Ide K, Morimoto H, Tahara H, Ohdan H.

PLoS One. 2013;8(3):e58359. doi: 10.1371/journal.pone.0058359. Epub 2013 Mar 5.

15.

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

Majeti R, Chao MP, Alizadeh AA, Pang WW, Jaiswal S, Gibbs KD Jr, van Rooijen N, Weissman IL.

Cell. 2009 Jul 23;138(2):286-99. doi: 10.1016/j.cell.2009.05.045.

16.

"Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosis.

Ho CC, Guo N, Sockolosky JT, Ring AM, Weiskopf K, Özkan E, Mori Y, Weissman IL, Garcia KC.

J Biol Chem. 2015 May 15;290(20):12650-63. doi: 10.1074/jbc.M115.648220. Epub 2015 Apr 2.

17.

The CD47-SIRPα signalling system: its physiological roles and therapeutic application.

Murata Y, Kotani T, Ohnishi H, Matozaki T.

J Biochem. 2014 Jun;155(6):335-44. doi: 10.1093/jb/mvu017. Epub 2014 Mar 12. Review.

PMID:
24627525
18.

Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.

Ide K, Wang H, Tahara H, Liu J, Wang X, Asahara T, Sykes M, Yang YG, Ohdan H.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5062-6. Epub 2007 Mar 12.

19.

Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.

Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K.

Blood. 2012 Nov 8;120(19):4058-67. doi: 10.1182/blood-2012-02-408864. Epub 2012 Sep 18.

20.

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