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Items: 1 to 20 of 178

1.

Inhibition of carbonic anhydrase IX: a new strategy against cancer.

Winum JY, Scozzafava A, Montero JL, Supuran CT.

Anticancer Agents Med Chem. 2009 Jul;9(6):693-702. Review.

PMID:
19601749
2.

Carbonic anhydrase IX: a new druggable target for the design of antitumor agents.

Winum JY, Rami M, Scozzafava A, Montero JL, Supuran C.

Med Res Rev. 2008 May;28(3):445-63. Review.

PMID:
17880011
3.

Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII.

Guler OO, De Simone G, Supuran CT.

Curr Med Chem. 2010;17(15):1516-26. Review.

PMID:
20166929
4.

Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with lipophilic sulfonamides.

Franchi M, Vullo D, Gallori E, Pastorek J, Russo A, Scozzafava A, Pastorekova S, Supuran CT.

J Enzyme Inhib Med Chem. 2003 Aug;18(4):333-8.

PMID:
14567548
6.

[Progress in the study of carbonic anhydrase inhibitors as potential anticancer drugs].

Guo J, Li FR, Liu Y, Cheng MS.

Yao Xue Xue Bao. 2013 Nov;48(11):1637-43. Review. Chinese.

PMID:
24475699
7.

Targeting tumor-associated carbonic anhydrase IX in cancer therapy.

Thiry A, Dogné JM, Masereel B, Supuran CT.

Trends Pharmacol Sci. 2006 Nov;27(11):566-73. Epub 2006 Sep 25.

PMID:
16996620
8.

Differential in vitro inhibitory effects of anticancer drugs on tumor-associated carbonic anhydrase isozymes CA IX and CA XII.

Ozensoy Guler O, Arslan O, Kockar F.

Methods Find Exp Clin Pharmacol. 2008 Jun;30(5):335-40. doi: 10.1358/mf.2008.30.5.1143022.

PMID:
18806891
9.

Carbonic anhydrase IX inhibitors in cancer therapy: an update.

Supuran CT, Winum JY.

Future Med Chem. 2015;7(11):1407-14. doi: 10.4155/fmc.15.71. Review.

PMID:
26230880
10.

Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.

Pastorekova S, Casini A, Scozzafava A, Vullo D, Pastorek J, Supuran CT.

Bioorg Med Chem Lett. 2004 Feb 23;14(4):869-73.

PMID:
15012984
11.

Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.

Cecchi A, Hulikova A, Pastorek J, Pastoreková S, Scozzafava A, Winum JY, Montero JL, Supuran CT.

J Med Chem. 2005 Jul 28;48(15):4834-41.

PMID:
16033263
12.

Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.

Puccetti L, Fasolis G, Cecchi A, Winum JY, Gamberi A, Montero JL, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett. 2005 May 2;15(9):2359-64.

PMID:
15837325
13.

Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties.

Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R.

Biochemistry. 2009 Feb 17;48(6):1322-31. doi: 10.1021/bi802035f.

14.

Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX.

Sharma A, Tiwari M, Supuran CT.

J Enzyme Inhib Med Chem. 2014 Apr;29(2):292-6. doi: 10.3109/14756366.2013.777334. Epub 2013 Mar 14.

PMID:
23488741
15.

Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.

Morris JC, Chiche J, Grellier C, Lopez M, Bornaghi LF, Maresca A, Supuran CT, Pouysségur J, Poulsen SA.

J Med Chem. 2011 Oct 13;54(19):6905-18. doi: 10.1021/jm200892s. Epub 2011 Sep 2.

PMID:
21851094
16.

Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

Vullo D, Franchi M, Gallori E, Pastorek J, Scozzafava A, Pastorekova S, Supuran CT.

Bioorg Med Chem Lett. 2003 Mar 24;13(6):1005-9.

PMID:
12643899
17.

Selective carbonic anhydrase IX inhibitors based on coumarin scaffold as promising antimetastatic agents: WO2012070024.

Carradori S.

Expert Opin Ther Pat. 2013;23(6):751-6. doi: 10.1517/13543776.2013.769523. Epub 2013 Feb 7.

PMID:
23387899
18.

Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with polyfluorinated aromatic/heterocyclic sulfonamides.

Pastorekova S, Vullo D, Casini A, Scozzafava A, Pastorek J, Nishimori I, Supuran CT.

J Enzyme Inhib Med Chem. 2005 Jun;20(3):211-7.

PMID:
16119190
19.

Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.

Garaj V, Puccetti L, Fasolis G, Winum JY, Montero JL, Scozzafava A, Vullo D, Innocenti A, Supuran CT.

Bioorg Med Chem Lett. 2005 Jun 15;15(12):3102-8.

PMID:
15905091
20.

Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating hydrazino moieties.

Winum JY, Dogné JM, Casini A, de Leval X, Montero JL, Scozzafava A, Vullo D, Innocenti A, Supuran CT.

J Med Chem. 2005 Mar 24;48(6):2121-5.

PMID:
15771455

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