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Items: 1 to 20 of 94

1.

Mitochondrial targeting of a catalase transgene product by plasmid liposomes increases radioresistance in vitro and in vivo.

Epperly MW, Melendez JA, Zhang X, Nie S, Pearce L, Peterson J, Franicola D, Dixon T, Greenberger BA, Komanduri P, Wang H, Greenberger JS.

Radiat Res. 2009 May;171(5):588-95. doi: 10.1667/RR1424.1.

2.

Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene.

Zhang X, Epperly MW, Kay MA, Chen ZY, Dixon T, Franicola D, Greenberger BA, Komanduri P, Greenberger JS.

Hum Gene Ther. 2008 Aug;19(8):820-6. doi: 10.1089/hum.2007.141.

4.

Mitochondrial localization of superoxide dismutase is required for decreasing radiation-induced cellular damage.

Epperly MW, Gretton JE, Sikora CA, Jefferson M, Bernarding M, Nie S, Greenberger JS.

Radiat Res. 2003 Nov;160(5):568-78.

PMID:
14565825
5.
7.

Ascorbate as a "redox sensor" and protector against irradiation-induced oxidative stress in 32D CL 3 hematopoietic cells and subclones overexpressing human manganese superoxide dismutase.

Epperly MW, Osipov AN, Martin I, Kawai KK, Borisenko GG, Tyurina YY, Jefferson M, Bernarding M, Greenberger JS, Kagan VE.

Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):851-61.

PMID:
14967442
8.

Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation.

Epperly MW, Defilippi S, Sikora C, Gretton J, Kalend A, Greenberger JS.

Gene Ther. 2000 Jun;7(12):1011-8.

9.

Overexpression of the MnSOD transgene product protects cryopreserved bone marrow hematopoietic progenitor cells from ionizing radiation.

Epperly MW, Epperly LD, Niu Y, Wang H, Zhang X, Franicola D, Greenberger JS.

Radiat Res. 2007 Nov;168(5):560-6.

PMID:
17973554
10.

Inhalation delivery of manganese superoxide dismutase-plasmid/liposomes protects the murine lung from irradiation damage.

Carpenter M, Epperly MW, Agarwal A, Nie S, Hricisak L, Niu Y, Greenberger JS.

Gene Ther. 2005 Apr;12(8):685-93.

PMID:
15750616
11.

Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase transgene.

Stickle RL, Epperly MW, Klein E, Bray JA, Greenberger JS.

Radiat Oncol Investig. 1999;7(4):204-17.

PMID:
10492161
12.

Manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) administration protects mice from esophagitis associated with fractionated radiation.

Epperly MW, Kagan VE, Sikora CA, Gretton JE, Defilippi SJ, Bar-Sagi D, Greenberger JS.

Int J Cancer. 2001 Aug 20;96(4):221-31.

13.

Modulation of radiation-induced cytokine elevation associated with esophagitis and esophageal stricture by manganese superoxide dismutase-plasmid/liposome (SOD2-PL) gene therapy.

Epperly MW, Gretton JA, DeFilippi SJ, Greenberger JS, Sikora CA, Liggitt D, Koe G.

Radiat Res. 2001 Jan;155(1 Pt 1):2-14.

PMID:
11121210
14.

Effects of MnSOD-plasmid liposome gene therapy on antioxidant levels in irradiated murine oral cavity orthotopic tumors.

Epperly MW, Wegner R, Kanai AJ, Kagan V, Greenberger EE, Nie S, Greenberger JS.

Radiat Res. 2007 Mar;167(3):289-97.

PMID:
17316075
15.

Cell phenotype specific kinetics of expression of intratracheally injected manganese superoxide dismutase-plasmid/liposomes (MnSOD-PL) during lung radioprotective gene therapy.

Epperly MW, Guo HL, Jefferson M, Nie S, Gretton J, Bernarding M, Bar-Sagi D, Archer H, Greenberger JS.

Gene Ther. 2003 Jan;10(2):163-71.

PMID:
12571645
16.

Manganese superoxide dismutase (SOD2) inhibits radiation-induced apoptosis by stabilization of the mitochondrial membrane.

Epperly MW, Sikora CA, DeFilippi SJ, Gretton JA, Zhan Q, Kufe DW, Greenberger JS.

Radiat Res. 2002 May;157(5):568-77.

PMID:
11966323
17.

Pulmonary irradiation-induced expression of VCAM-I and ICAM-I is decreased by manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) gene therapy.

Epperly MW, Sikora CA, DeFilippi SJ, Gretton JE, Bar-Sagi D, Archer H, Carlos T, Guo H, Greenberger JS.

Biol Blood Marrow Transplant. 2002;8(4):175-87.

PMID:
12014807
18.

Erythropoietin increases the radioresistance of a clonal hematopoietic progenitor cell line expressing a transgene for the erythropoietin receptor.

Santucci MA, Pierce JH, Zannini S, Fortuna A, Frezza G, Babini L, Rosenstein MM, Greenberger JS.

Stem Cells. 1994 Sep;12(5):506-13.

PMID:
7804124
19.

Plasmid/liposome transfer of the human manganese superoxide dismutase transgene prevents ionizing irradiation-induced apoptosis in human esophagus organ explant culture.

Epperly MW, Sikora C, Defilippi S, Bray J, Koe G, Liggitt D, Luketich JD, Greenberger JS.

Int J Cancer. 2000 Jun 20;90(3):128-37.

20.

The v-abl, c-fms, or v-myc oncogene induces gamma radiation resistance of hematopoietic progenitor cell line 32d cl 3 at clinical low dose rate.

FitzGerald TJ, Santucci MA, Das I, Kase K, Pierce JH, Greenberger JS.

Int J Radiat Oncol Biol Phys. 1991 Oct;21(5):1203-10.

PMID:
1938518

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