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Items: 1 to 20 of 99

1.

Alpha interferon induces long-lasting refractoriness of JAK-STAT signaling in the mouse liver through induction of USP18/UBP43.

Sarasin-Filipowicz M, Wang X, Yan M, Duong FH, Poli V, Hilton DJ, Zhang DE, Heim MH.

Mol Cell Biol. 2009 Sep;29(17):4841-51. doi: 10.1128/MCB.00224-09. Epub 2009 Jun 29.

2.

Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation.

Dill MT, Makowska Z, Trincucci G, Gruber AJ, Vogt JE, Filipowicz M, Calabrese D, Krol I, Lau DT, Terracciano L, van Nimwegen E, Roth V, Heim MH.

J Clin Invest. 2014 Apr;124(4):1568-81. doi: 10.1172/JCI70408. Epub 2014 Feb 24.

3.

SOCS1 is an inducible negative regulator of interferon λ (IFN-λ)-induced gene expression in vivo.

Blumer T, Coto-Llerena M, Duong FHT, Heim MH.

J Biol Chem. 2017 Oct 27;292(43):17928-17938. doi: 10.1074/jbc.M117.788877. Epub 2017 Sep 12.

PMID:
28900038
4.

Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C.

Huang Y, Feld JJ, Sapp RK, Nanda S, Lin JH, Blatt LM, Fried MW, Murthy K, Liang TJ.

Gastroenterology. 2007 Feb;132(2):733-44. Epub 2006 Nov 29.

5.

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity.

Malakhova OA, Kim KI, Luo JK, Zou W, Kumar KG, Fuchs SY, Shuai K, Zhang DE.

EMBO J. 2006 Jun 7;25(11):2358-67. Epub 2006 May 18.

6.

Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo.

Makowska Z, Duong FH, Trincucci G, Tough DF, Heim MH.

Hepatology. 2011 Apr;53(4):1154-63. doi: 10.1002/hep.24189.

PMID:
21480323
7.

Functional conservation of suppressors of cytokine signaling proteins between teleosts and mammals: Atlantic salmon SOCS1 binds to JAK/STAT family members and suppresses type I and II IFN signaling.

Skjesol A, Liebe T, Iliev DB, Thomassen EI, Tollersrud LG, Sobhkhez M, Lindenskov Joensen L, Secombes CJ, Jørgensen JB.

Dev Comp Immunol. 2014 Jul;45(1):177-89. doi: 10.1016/j.dci.2014.02.009. Epub 2014 Feb 28.

PMID:
24582990
8.

Suppressors of cytokine signaling modulate JAK/STAT-mediated cell responses during atherosclerosis.

Ortiz-Muñoz G, Martin-Ventura JL, Hernandez-Vargas P, Mallavia B, Lopez-Parra V, Lopez-Franco O, Muñoz-Garcia B, Fernandez-Vizarra P, Ortega L, Egido J, Gomez-Guerrero C.

Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):525-31. doi: 10.1161/ATVBAHA.108.173781. Epub 2009 Jan 22.

9.

miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling.

Collins AS, McCoy CE, Lloyd AT, O'Farrelly C, Stevenson NJ.

PLoS One. 2013 Jul 22;8(7):e69090. doi: 10.1371/journal.pone.0069090. Print 2013.

10.

Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression.

MacParland SA, Ma XZ, Chen L, Khattar R, Cherepanov V, Selzner M, Feld JJ, Selzner N, McGilvray ID.

J Virol. 2016 May 27;90(12):5549-60. doi: 10.1128/JVI.02557-15. Print 2016 Jun 15.

11.
12.

Usp18 promotes conventional CD11b+ dendritic cell development.

Cong XL, Lo MC, Reuter BA, Yan M, Fan JB, Zhang DE.

J Immunol. 2012 May 15;188(10):4776-81. doi: 10.4049/jimmunol.1101609. Epub 2012 Apr 9.

13.

Respiratory Syncytial Virus Nonstructural Proteins Upregulate SOCS1 and SOCS3 in the Different Manner from Endogenous IFN Signaling.

Zheng J, Yang P, Tang Y, Pan Z, Zhao D.

J Immunol Res. 2015;2015:738547. doi: 10.1155/2015/738547. Epub 2015 Oct 18.

14.

SOCS1 silencing enhances antitumor activity of type I IFNs by regulating apoptosis in neuroendocrine tumor cells.

Zitzmann K, Brand S, De Toni EN, Baehs S, Göke B, Meinecke J, Spöttl G, Meyer HH, Auernhammer CJ.

Cancer Res. 2007 May 15;67(10):5025-32.

15.

IFN-alpha-induced signal transduction, gene expression, and antitumor activity of immune effector cells are negatively regulated by suppressor of cytokine signaling proteins.

Zimmerer JM, Lesinski GB, Kondadasula SV, Karpa VI, Lehman A, Raychaudhury A, Becknell B, Carson WE 3rd.

J Immunol. 2007 Apr 15;178(8):4832-45.

16.

Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes.

Norkina O, Dolganiuc A, Catalano D, Kodys K, Mandrekar P, Syed A, Efros M, Szabo G.

Alcohol Clin Exp Res. 2008 Sep;32(9):1565-73. doi: 10.1111/j.1530-0277.2008.00726.x. Epub 2008 Jul 9.

17.

Inhibition of microRNA‑155 relieves sepsis‑induced liver injury through inactivating the JAK/STAT pathway.

Lv X, Zhang Y, Cui Y, Ren Y, Li R, Rong Q.

Mol Med Rep. 2015 Oct;12(4):6013-8. doi: 10.3892/mmr.2015.4188. Epub 2015 Aug 5.

PMID:
26251957
18.

Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages.

Zou W, Kim JH, Handidu A, Li X, Kim KI, Yan M, Li J, Zhang DE.

Biochem Biophys Res Commun. 2007 Apr 27;356(1):193-9. Epub 2007 Feb 28.

19.

"Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells.

Trilling M, Le VT, Rashidi-Alavijeh J, Katschinski B, Scheller J, Rose-John S, Androsiac GE, Jonjic S, Poli V, Pfeffer K, Hengel H.

J Immunol. 2014 Jan 1;192(1):447-58. doi: 10.4049/jimmunol.1203516. Epub 2013 Dec 6.

20.

Suppressor of cytokine signaling expression with increasing severity of murine hepatic ischemia-reperfusion injury.

Langdale LA, Hoagland V, Benz W, Riehle KJ, Campbell JS, Liggitt DH, Fausto N.

J Hepatol. 2008 Aug;49(2):198-206. doi: 10.1016/j.jhep.2008.03.014. Epub 2008 May 8.

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