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HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.

Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, Sékaly RP.

Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21.


The role of cytokines in the establishment, persistence and eradication of the HIV reservoir.

Vandergeeten C, Fromentin R, Chomont N.

Cytokine Growth Factor Rev. 2012 Aug-Oct;23(4-5):143-9. doi: 10.1016/j.cytogfr.2012.05.001. Epub 2012 Jun 27. Review.


Th1/17 Polarization of CD4 T Cells Supports HIV-1 Persistence during Antiretroviral Therapy.

Sun H, Kim D, Li X, Kiselinova M, Ouyang Z, Vandekerckhove L, Shang H, Rosenberg ES, Yu XG, Lichterfeld M.

J Virol. 2015 Nov;89(22):11284-93. doi: 10.1128/JVI.01595-15. Epub 2015 Sep 2.


Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure.

Ruff CT, Ray SC, Kwon P, Zinn R, Pendleton A, Hutton N, Ashworth R, Gange S, Quinn TC, Siliciano RF, Persaud D.

J Virol. 2002 Sep;76(18):9481-92.


A reservoir for HIV in patients on combination antiretroviral therapy.

Siliciano RF.

Hopkins HIV Rep. 1998 Jan;10(1):1, 5-6, 11.


A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children.

Persaud D, Pierson T, Ruff C, Finzi D, Chadwick KR, Margolick JB, Ruff A, Hutton N, Ray S, Siliciano RF.

J Clin Invest. 2000 Apr;105(7):995-1003.


The challenge of viral reservoirs in HIV-1 infection.

Blankson JN, Persaud D, Siliciano RF.

Annu Rev Med. 2002;53:557-93. Review.


A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs.

Lassen KG, Hebbeler AM, Bhattacharyya D, Lobritz MA, Greene WC.

PLoS One. 2012;7(1):e30176. doi: 10.1371/journal.pone.0030176. Epub 2012 Jan 24.


Stochastic population switch may explain the latent reservoir stability and intermittent viral blips in HIV patients on suppressive therapy.

Wang S, Rong L.

J Theor Biol. 2014 Nov 7;360:137-48. doi: 10.1016/j.jtbi.2014.06.042. Epub 2014 Jul 10.


Human immunodeficiency virus type 1 (HIV-1) antigen secretion by latently infected resting CD4+ T lymphocytes from HIV-1-infected individuals.

Fondere JM, Petitjean G, Huguet MF, Salhi SL, Baillat V, Macura-Biegun A, Becquart P, Reynes J, Vendrell JP.

J Virol. 2004 Oct;78(19):10536-42. Erratum in: J Virol. 2004 Nov;78(22):12722. Macura-Biegum, Anna [corrected to Macura-Biegun, Anna].


Low-level HIV-1 replication and the dynamics of the resting CD4+ T cell reservoir for HIV-1 in the setting of HAART.

Sedaghat AR, Siliciano RF, Wilke CO.

BMC Infect Dis. 2008 Jan 2;8:2. doi: 10.1186/1471-2334-8-2.


Latently infected cell activation: a way to reduce the size of the HIV reservoir?

Forde J, Volpe JM, Ciupe SM.

Bull Math Biol. 2012 Jul;74(7):1651-72. doi: 10.1007/s11538-012-9729-x. Epub 2012 May 5.


Reduction of the HIV-1-infected T-cell reservoir by immune activation treatment is dose-dependent and restricted by the potency of antiretroviral drugs.

Fraser C, Ferguson NM, Ghani AC, Prins JM, Lange JM, Goudsmit J, Anderson RM, de Wolf F.

AIDS. 2000 Apr 14;14(6):659-69.


Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy.

Rong L, Perelson AS.

PLoS Comput Biol. 2009 Oct;5(10):e1000533. doi: 10.1371/journal.pcbi.1000533. Epub 2009 Oct 16.


Modeling HIV persistence, the latent reservoir, and viral blips.

Rong L, Perelson AS.

J Theor Biol. 2009 Sep 21;260(2):308-31. doi: 10.1016/j.jtbi.2009.06.011. Epub 2009 Jun 17. Review.


Interleukin-7 promotes HIV persistence during antiretroviral therapy.

Vandergeeten C, Fromentin R, DaFonseca S, Lawani MB, Sereti I, Lederman MM, Ramgopal M, Routy JP, Sékaly RP, Chomont N.

Blood. 2013 May 23;121(21):4321-9. doi: 10.1182/blood-2012-11-465625. Epub 2013 Apr 15.


Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy.

Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, Quinn TC, Chadwick K, Margolick J, Brookmeyer R, Gallant J, Markowitz M, Ho DD, Richman DD, Siliciano RF.

Science. 1997 Nov 14;278(5341):1295-300.


Long-term immunological response in HIV-1-infected subjects receiving potent antiretroviral therapy.

Kaufmann GR, Bloch M, Zaunders JJ, Smith D, Cooper DA.

AIDS. 2000 May 26;14(8):959-69.


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