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Items: 1 to 20 of 126

1.

Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta.

Palmer JC, Baig S, Kehoe PG, Love S.

Am J Pathol. 2009 Jul;175(1):262-70. doi: 10.2353/ajpath.2009.081054. Epub 2009 Jun 18.

2.

Endothelin-converting enzyme-1 in Alzheimer's disease and vascular dementia.

Palmer JC, Kehoe PG, Love S.

Neuropathol Appl Neurobiol. 2010 Oct;36(6):487-97. doi: 10.1111/j.1365-2990.2010.01084.x. Epub 2010 Mar 22.

PMID:
20345647
3.

Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-β.

Palmer JC, Barker R, Kehoe PG, Love S.

J Alzheimers Dis. 2012;29(4):853-61. doi: 10.3233/JAD-2012-111760.

PMID:
22330820
4.

Endothelin-converting enzyme-1 activity, endothelin-1 production, and free radical-dependent vasoconstriction in Alzheimer's disease.

Palmer JC, Tayler HM, Love S.

J Alzheimers Dis. 2013;36(3):577-87. doi: 10.3233/JAD-130383.

PMID:
23629587
5.

Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.

Wang S, Wang R, Chen L, Bennett DA, Dickson DW, Wang DS.

J Neurochem. 2010 Oct;115(1):47-57. doi: 10.1111/j.1471-4159.2010.06899.x. Epub 2010 Jul 30.

6.

Endothelin receptor antagonists: potential in Alzheimer's disease.

Palmer J, Love S.

Pharmacol Res. 2011 Jun;63(6):525-31. doi: 10.1016/j.phrs.2010.12.008. Epub 2010 Dec 27. Review.

PMID:
21193044
7.
8.

Endothelin-converting enzymes degrade intracellular β-amyloid produced within the endosomal/lysosomal pathway and autophagosomes.

Pacheco-Quinto J, Eckman EA.

J Biol Chem. 2013 Feb 22;288(8):5606-15. doi: 10.1074/jbc.M112.422964. Epub 2013 Jan 2.

9.

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme.

Eckman EA, Watson M, Marlow L, Sambamurti K, Eckman CB.

J Biol Chem. 2003 Jan 24;278(4):2081-4. Epub 2002 Dec 2.

10.

Endothelin-converting enzyme-1 is expressed in human cerebral cortex and protects against Alzheimer's disease.

Funalot B, Ouimet T, Claperon A, Fallet C, Delacourte A, Epelbaum J, Subkowski T, Léonard N, Codron V, David JP, Amouyel P, Schwartz JC, Helbecque N.

Mol Psychiatry. 2004 Dec;9(12):1122-8, 1059.

PMID:
15340356
11.

Neprilysin deficiency alters the neuropathological and behavioral phenotype in the 5XFAD mouse model of Alzheimer's disease.

Hüttenrauch M, Baches S, Gerth J, Bayer TA, Weggen S, Wirths O.

J Alzheimers Dis. 2015;44(4):1291-302. doi: 10.3233/JAD-142463.

PMID:
25408216
12.

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme.

Eckman EA, Reed DK, Eckman CB.

J Biol Chem. 2001 Jul 6;276(27):24540-8. Epub 2001 May 3.

13.

Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes.

Pihlaja R, Koistinaho J, Kauppinen R, Sandholm J, Tanila H, Koistinaho M.

Glia. 2011 Nov;59(11):1643-57. doi: 10.1002/glia.21212. Epub 2011 Aug 8.

PMID:
21826742
14.

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.

Li R, Lindholm K, Yang LB, Yue X, Citron M, Yan R, Beach T, Sue L, Sabbagh M, Cai H, Wong P, Price D, Shen Y.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3632-7. Epub 2004 Feb 20.

15.

Cellular distribution of the endothelin system in the human brain.

Naidoo V, Naidoo S, Mahabeer R, Raidoo DM.

J Chem Neuroanat. 2004 May;27(2):87-98.

PMID:
15121213
16.

Impaired amyloid β-degrading enzymes in brain of streptozotocin-induced diabetic rats.

Liu Y, Liu L, Lu S, Wang D, Liu X, Xie L, Wang G.

J Endocrinol Invest. 2011 Jan;34(1):26-31. doi: 10.3275/6995. Epub 2010 Apr 22. Erratum in: J Endocrinol Invest. 2011 Feb;34(2):169.

PMID:
20414044
17.

Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme.

Eckman EA, Adams SK, Troendle FJ, Stodola BA, Kahn MA, Fauq AH, Xiao HD, Bernstein KE, Eckman CB.

J Biol Chem. 2006 Oct 13;281(41):30471-8. Epub 2006 Aug 14.

18.
19.

In vivo role of endothelin-converting enzyme-1 as examined by adenovirus-mediated overexpression in rats.

Télémaque S, Emoto N, deWit D, Yanagisawa M.

J Cardiovasc Pharmacol. 1998;31 Suppl 1:S548-50.

PMID:
9595539
20.

The peptidase inhibitor CGS-26303 increases endothelin converting enzyme-1 expression in endothelial cells through accumulation of big endothelin-1.

Raoch V, Martinez-Miguel P, Arribas-Gomez I, Rodriguez-Puyol M, Rodriguez-Puyol D, Lopez-Ongil S.

Br J Pharmacol. 2007 Oct;152(3):313-22. Epub 2007 Jul 23.

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