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CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract.

Beswick EJ, Reyes VE.

World J Gastroenterol. 2009 Jun 21;15(23):2855-61. Review.


Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex.

Le Hiress M, Tu L, Ricard N, Phan C, Thuillet R, Fadel E, Dorfmüller P, Montani D, de Man F, Humbert M, Huertas A, Guignabert C.

Am J Respir Crit Care Med. 2015 Oct 15;192(8):983-97. doi: 10.1164/rccm.201402-0322OC.


Essential role for macrophage migration inhibitory factor in gastritis induced by Helicobacter pylori.

Wong BL, Zhu SL, Huang XR, Ma J, Xia HH, Bucala R, Wong BC, Lan HY.

Am J Pathol. 2009 Apr;174(4):1319-28. doi: 10.2353/ajpath.2009.080708. Epub 2009 Mar 12.


The multifaceted roles of the invariant chain CD74--More than just a chaperone.

Schröder B.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1269-81. doi: 10.1016/j.bbamcr.2016.03.026. Epub 2016 Mar 28. Review.


Migration inhibitory factor enhances inflammation via CD74 in cartilage end plates with Modic type 1 changes on MRI.

Xiong C, Huang B, Cun Y, Aghdasi BG, Zhou Y.

Clin Orthop Relat Res. 2014 Jun;472(6):1943-54. doi: 10.1007/s11999-014-3508-y. Epub 2014 Feb 26.


Functional roles of HIV-1 Vpu and CD74: Details and implications of the Vpu-CD74 interaction.

Le Noury DA, Mosebi S, Papathanasopoulos MA, Hewer R.

Cell Immunol. 2015 Nov-Dec;298(1-2):25-32. doi: 10.1016/j.cellimm.2015.08.005. Epub 2015 Aug 24. Review.


Ectopic expression of CD74 in Ikkβ-deleted mouse hepatocytes.

Koch KS, Leffert HL.

Acta Histochem. 2011 Jul;113(4):428-35. doi: 10.1016/j.acthis.2010.03.004. Epub 2010 Jun 1.


Helicobacter pylori-induced IL-8 production by gastric epithelial cells up-regulates CD74 expression.

Beswick EJ, Das S, Pinchuk IV, Adegboyega P, Suarez G, Yamaoka Y, Reyes VE.

J Immunol. 2005 Jul 1;175(1):171-6.


Macrophage migration inhibitory factor triggers chemotaxis of CD74+CXCR2+ NKT cells in chemically induced IFN-γ-mediated skin inflammation.

Hsieh CY, Chen CL, Lin YS, Yeh TM, Tsai TT, Hong MY, Lin CF.

J Immunol. 2014 Oct 1;193(7):3693-703. doi: 10.4049/jimmunol.1400692. Epub 2014 Aug 29.


MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling.

Klasen C, Ohl K, Sternkopf M, Shachar I, Schmitz C, Heussen N, Hobeika E, Levit-Zerdoun E, Tenbrock K, Reth M, Bernhagen J, El Bounkari O.

J Immunol. 2014 Jun 1;192(11):5273-84. doi: 10.4049/jimmunol.1302209. Epub 2014 Apr 23.


The Helicobacter pylori urease B subunit binds to CD74 on gastric epithelial cells and induces NF-kappaB activation and interleukin-8 production.

Beswick EJ, Pinchuk IV, Minch K, Suarez G, Sierra JC, Yamaoka Y, Reyes VE.

Infect Immun. 2006 Feb;74(2):1148-55.


Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects.

Benedek G, Meza-Romero R, Andrew S, Leng L, Burrows GG, Bourdette D, Offner H, Bucala R, Vandenbark AA.

Eur J Immunol. 2013 May;43(5):1309-21. doi: 10.1002/eji.201243162. Epub 2013 Apr 10.


Helicobacter pylori binds to CD74 on gastric epithelial cells and stimulates interleukin-8 production.

Beswick EJ, Bland DA, Suarez G, Barrera CA, Fan X, Reyes VE.

Infect Immun. 2005 May;73(5):2736-43.


Business as usual: the p35 isoform of human CD74 retains function in antigen presentation.

Bergmann H.

Immunol Cell Biol. 2012 Oct;90(9):839-40. doi: 10.1038/icb.2012.51. Epub 2012 Oct 2. No abstract available.


Both host and parasite MIF molecules bind to chicken macrophages via CD74 surface receptor.

Kim S, Cox CM, Jenkins MC, Fetterer RH, Miska KB, Dalloul RA.

Dev Comp Immunol. 2014 Dec;47(2):319-26. doi: 10.1016/j.dci.2014.07.021. Epub 2014 Jul 30.


CD74: an emerging opportunity as a therapeutic target in cancer and autoimmune disease.

Borghese F, Clanchy FI.

Expert Opin Ther Targets. 2011 Mar;15(3):237-51. doi: 10.1517/14728222.2011.550879. Epub 2011 Jan 6. Review.


The biological function and significance of CD74 in immune diseases.

Su H, Na N, Zhang X, Zhao Y.

Inflamm Res. 2017 Mar;66(3):209-216. doi: 10.1007/s00011-016-0995-1. Epub 2016 Oct 17. Review.


Porcine CD74 is involved in the inflammatory response activated by nuclear factor kappa B during porcine circovirus type 2 (PCV-2) infection.

Zhang H, Liu C, Cheng S, Wang X, Li W, Charreyre C, Audonnet JC, He Q.

Arch Virol. 2013 Nov;158(11):2285-95. doi: 10.1007/s00705-013-1750-3. Epub 2013 Jun 5.


The macrophage migration inhibitory factor homolog of Entamoeba histolytica binds to and immunomodulates host macrophages.

Moonah SN, Abhyankar MM, Haque R, Petri WA Jr.

Infect Immun. 2014 Sep;82(9):3523-30. doi: 10.1128/IAI.01812-14. Epub 2014 May 12.

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