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Items: 1 to 20 of 82

1.

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.

Gupta A, Yang Q, Pandita RK, Hunt CR, Xiang T, Misri S, Zeng S, Pagan J, Jeffery J, Puc J, Kumar R, Feng Z, Powell SN, Bhat A, Yaguchi T, Wadhwa R, Kaul SC, Parsons R, Khanna KK, Pandita TK.

Cell Cycle. 2009 Jul 15;8(14):2198-210.

PMID:
19502790
2.

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.

Fraser M, Harding SM, Zhao H, Coackley C, Durocher D, Bristow RG.

Cell Cycle. 2011 Jul 1;10(13):2218-32.

PMID:
21623170
3.

Alteration/deficiency in activation-3 (Ada3) plays a critical role in maintaining genomic stability.

Mirza S, Katafiasz BJ, Kumar R, Wang J, Mohibi S, Jain S, Gurumurthy CB, Pandita TK, Dave BJ, Band H, Band V.

Cell Cycle. 2012 Nov 15;11(22):4266-74. doi: 10.4161/cc.22613.

4.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016.

PMID:
19583974
5.

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.

Bolderson E, Tomimatsu N, Richard DJ, Boucher D, Kumar R, Pandita TK, Burma S, Khanna KK.

Nucleic Acids Res. 2010 Apr;38(6):1821-31. doi: 10.1093/nar/gkp1164.

6.

ATM-dependent phosphorylation of the checkpoint clamp regulates repair pathways and maintains genomic stability.

Shin MH, Yuan M, Zhang H, Margolick JB, Kai M.

Cell Cycle. 2012 May 1;11(9):1796-803. doi: 10.4161/cc.20161.

7.

Attenuation of PTEN perturbs genomic stability via activation of Akt and down-regulation of Rad51 in human embryonic kidney cells.

Mukherjee A, Karmakar P.

Mol Carcinog. 2013 Aug;52(8):611-8. doi: 10.1002/mc.21903.

PMID:
22488521
8.

Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress.

Bassi C, Ho J, Srikumar T, Dowling RJ, Gorrini C, Miller SJ, Mak TW, Neel BG, Raught B, Stambolic V.

Science. 2013 Jul 26;341(6144):395-9. doi: 10.1126/science.1236188. Erratum in: Science. 2013 Sep 6;341(6150):1064.

10.

Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells.

Martín M, Terradas M, Iliakis G, Tusell L, Genescà A.

Genes Chromosomes Cancer. 2009 Sep;48(9):745-59. doi: 10.1002/gcc.20679.

PMID:
19455703
11.

The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.

PMID:
19442252
12.

ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.

Gatei M, Jakob B, Chen P, Kijas AW, Becherel OJ, Gueven N, Birrell G, Lee JH, Paull TT, Lerenthal Y, Fazry S, Taucher-Scholz G, Kalb R, Schindler D, Waltes R, Dörk T, Lavin MF.

J Biol Chem. 2011 Sep 9;286(36):31542-56. doi: 10.1074/jbc.M111.258152.

13.

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.

Takemura H, Rao VA, Sordet O, Furuta T, Miao ZH, Meng L, Zhang H, Pommier Y.

J Biol Chem. 2006 Oct 13;281(41):30814-23.

14.
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16.

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK.

Nature. 2008 May 29;453(7195):677-81. doi: 10.1038/nature06883.

PMID:
18449195
17.

An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells.

Krempler A, Deckbar D, Jeggo PA, Löbrich M.

Cell Cycle. 2007 Jul 15;6(14):1682-6. Review.

PMID:
17637566
18.

Telomeres, histone code, and DNA damage response.

Misri S, Pandita S, Kumar R, Pandita TK.

Cytogenet Genome Res. 2008;122(3-4):297-307. doi: 10.1159/000167816. Review.

19.

Activation of the S phase DNA damage checkpoint by mitomycin C.

Mladenov E, Tsaneva I, Anachkova B.

J Cell Physiol. 2007 May;211(2):468-76.

PMID:
17167777
20.

Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation.

Saha J, Wang M, Cucinotta FA.

DNA Repair (Amst). 2013 Dec;12(12):1143-51. doi: 10.1016/j.dnarep.2013.10.004.

PMID:
24238855

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