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Items: 1 to 20 of 107


Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.

Burkard ME, Maciejowski J, Rodriguez-Bravo V, Repka M, Lowery DM, Clauser KR, Zhang C, Shokat KM, Carr SA, Yaffe MB, Jallepalli PV.

PLoS Biol. 2009 May 5;7(5):e1000111. doi: 10.1371/journal.pbio.1000111.


Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation.

Wolfe BA, Takaki T, Petronczki M, Glotzer M.

PLoS Biol. 2009 May 5;7(5):e1000110. doi: 10.1371/journal.pbio.1000110.


Centralspindlin assembly and 2 phosphorylations on MgcRacGAP by Polo-like kinase 1 initiate Ect2 binding in early cytokinesis.

Kim H, Guo F, Brahma S, Xing Y, Burkard ME.

Cell Cycle. 2014;13(18):2952-61. doi: 10.4161/15384101.2014.947201.


Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly.

Pal D, Wu D, Haruta A, Matsumura F, Wei Q.

Cell Cycle. 2010 Oct 15;9(20):4117-29.


Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells.

Burkard ME, Randall CL, Larochelle S, Zhang C, Shokat KM, Fisher RP, Jallepalli PV.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4383-8.


Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1.

Neef R, Gruneberg U, Kopajtich R, Li X, Nigg EA, Sillje H, Barr FA.

Nat Cell Biol. 2007 Apr;9(4):436-44.


Polo-like kinase 1 directs the AMPK-mediated activation of myosin regulatory light chain at the cytokinetic cleavage furrow independently of energy balance.

Vazquez-Martin A, Cufí S, Oliveras-Ferraros C, Menendez JA.

Cell Cycle. 2012 Jul 1;11(13):2422-6. doi: 10.4161/cc.20438.


Cytokinesis and cancer: Polo loves ROCK'n' Rho(A).

Li J, Wang J, Jiao H, Liao J, Xu X.

J Genet Genomics. 2010 Mar;37(3):159-72. doi: 10.1016/S1673-8527(09)60034-5. Review.


Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis.

Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA.

J Cell Biol. 2003 Sep 1;162(5):863-75.


Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission.

Bastos RN, Barr FA.

J Cell Biol. 2010 Nov 15;191(4):751-60. doi: 10.1083/jcb.201008108.


Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.

Hu CK, Ozlü N, Coughlin M, Steen JJ, Mitchison TJ.

Mol Biol Cell. 2012 Jul;23(14):2702-11. doi: 10.1091/mbc.E12-01-0058.


An ECT2-centralspindlin complex regulates the localization and function of RhoA.

Yüce O, Piekny A, Glotzer M.

J Cell Biol. 2005 Aug 15;170(4):571-82.


Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.

Lowery DM, Clauser KR, Hjerrild M, Lim D, Alexander J, Kishi K, Ong SE, Gammeltoft S, Carr SA, Yaffe MB.

EMBO J. 2007 May 2;26(9):2262-73.


Polo-like kinase controls vertebrate spindle elongation and cytokinesis.

Brennan IM, Peters U, Kapoor TM, Straight AF.

PLoS One. 2007 May 2;2(5):e409.


The role of PLK1-phosphorylated SVIL in myosin II activation and cytokinetic furrowing.

Hasegawa H, Hyodo T, Asano E, Ito S, Maeda M, Kuribayashi H, Natsume A, Wakabayashi T, Hamaguchi M, Senga T.

J Cell Sci. 2013 Aug 15;126(Pt 16):3627-37. doi: 10.1242/jcs.124818.


Stabilization of anaphase midzone microtubules is regulated by Rho during cytokinesis in human fibrosarcoma cells.

Kanada M, Nagasaki A, Uyeda TQ.

Exp Cell Res. 2009 Oct 1;315(16):2705-14. doi: 10.1016/j.yexcr.2009.06.027.


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