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Items: 1 to 20 of 258


C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia.

Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M.

Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L286-98. doi: 10.1152/ajplung.00094.2009. Epub 2009 May 22.


CCAAT/enhancer binding protein-α regulates the protease/antiprotease balance required for bronchiolar epithelium regeneration.

Sato A, Xu Y, Whitsett JA, Ikegami M.

Am J Respir Cell Mol Biol. 2012 Oct;47(4):454-63. doi: 10.1165/rcmb.2011-0239OC. Epub 2012 May 31.


Silencing hyperoxia-induced C/EBPα in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells.

Yang G, Hinson MD, Bordner JE, Lin QS, Fernando AP, La P, Wright CJ, Dennery PA.

Am J Physiol Lung Cell Mol Physiol. 2011 Aug;301(2):L187-96. doi: 10.1152/ajplung.00082.2011. Epub 2011 May 13.


FGF signaling is required for pulmonary homeostasis following hyperoxia.

Hokuto I, Perl AK, Whitsett JA.

Am J Physiol Lung Cell Mol Physiol. 2004 Mar;286(3):L580-7. Epub 2003 Nov 14.


Mice lacking CCAAt/enhancer-binding protein-alpha show hyperproliferation of alveolar type II cells and increased surfactant protein mRNAs.

Sugahara K, Iyama KI, Kimura T, Sano K, Darlington GJ, Akiba T, Takiguchi M.

Cell Tissue Res. 2001 Oct;306(1):57-63.


Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice.

Besnard V, Matsuzaki Y, Clark J, Xu Y, Wert SE, Ikegami M, Stahlman MT, Weaver TE, Hunt AN, Postle AD, Whitsett JA.

Am J Physiol Lung Cell Mol Physiol. 2010 May;298(5):L646-59. doi: 10.1152/ajplung.00409.2009. Epub 2010 Feb 26.


Transgenic overexpression of granulocyte macrophage-colony stimulating factor in the lung prevents hyperoxic lung injury.

Paine R 3rd, Wilcoxen SE, Morris SB, Sartori C, Baleeiro CE, Matthay MA, Christensen PJ.

Am J Pathol. 2003 Dec;163(6):2397-406.


The effects of hyperoxia exposure on lung function and pulmonary surfactant in a rat model of acute lung injury.

Pace PW, Yao LJ, Wilson JX, Possmayer F, Veldhuizen RA, Lewis JF.

Exp Lung Res. 2009 Jun;35(5):380-98.


CCAAT/enhancer-binding protein-α suppresses lung tumor development in mice through the p38α MAP kinase pathway.

Sato A, Yamada N, Ogawa Y, Ikegami M.

PLoS One. 2013;8(2):e57013. doi: 10.1371/journal.pone.0057013. Epub 2013 Feb 20.


Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.

Xu Y, Ikegami M, Wang Y, Matsuzaki Y, Whitsett JA.

BMC Genomics. 2007 Dec 10;8:455.


C/EBPalpha is required for lung maturation at birth.

Martis PC, Whitsett JA, Xu Y, Perl AK, Wan H, Ikegami M.

Development. 2006 Mar;133(6):1155-64. Epub 2006 Feb 8.


Overexpression of Stat3C in pulmonary epithelium protects against hyperoxic lung injury.

Lian X, Qin Y, Hossain SA, Yang L, White A, Xu H, Shipley JM, Li T, Senior RM, Du H, Yan C.

J Immunol. 2005 Jun 1;174(11):7250-6.


Protein expression profile of rat type two alveolar epithelial cells during hyperoxic stress and recovery.

Bhargava M, Dey S, Becker T, Steinbach M, Wu B, Lee SM, Higgins L, Kumar V, Bitterman PB, Ingbar DH, Wendt CH.

Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L604-14. doi: 10.1152/ajplung.00079.2013. Epub 2013 Sep 6.


STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury.

Ikegami M, Falcone A, Whitsett JA.

J Appl Physiol (1985). 2008 Jun;104(6):1753-60. doi: 10.1152/japplphysiol.00875.2007. Epub 2008 Mar 27.


STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells.

Matsuzaki Y, Besnard V, Clark JC, Xu Y, Wert SE, Ikegami M, Whitsett JA.

Am J Respir Cell Mol Biol. 2008 May;38(5):551-8. Epub 2007 Dec 20.


Effect of hyperoxia on the composition of the alveolar surfactant and the turnover of surfactant phospholipids, cholesterol, plasmalogens and vitamin E.

Tölle A, Kolleck I, Schlame M, Wauer R, Stevens PA, Rüstow B.

Biochim Biophys Acta. 1997 Jun 2;1346(2):198-204.


Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts.

Besnard V, Wert SE, Stahlman MT, Postle AD, Xu Y, Ikegami M, Whitsett JA.

J Biol Chem. 2009 Feb 6;284(6):4018-30. doi: 10.1074/jbc.M805388200. Epub 2008 Dec 11.


Surfactant protein-B-deficient mice are susceptible to hyperoxic lung injury.

Tokieda K, Iwamoto HS, Bachurski C, Wert SE, Hull WM, Ikeda K, Whitsett JA.

Am J Respir Cell Mol Biol. 1999 Oct;21(4):463-72.


Differential expression of CCAAT enhancer binding protein family in rat alveolar epithelial cell proliferation and in acute lung injury.

Sugahara K, Sadohara T, Sugita M, Iyama K, Takiguchi M.

Cell Tissue Res. 1999 Aug;297(2):261-70.


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