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Items: 1 to 20 of 112

1.

Interleukin-33 is biologically active independently of caspase-1 cleavage.

Talabot-Ayer D, Lamacchia C, Gabay C, Palmer G.

J Biol Chem. 2009 Jul 17;284(29):19420-6. doi: 10.1074/jbc.M901744200. Epub 2009 May 22.

2.

A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing.

Gaggero A, De Ambrosis A, Mezzanzanica D, Piazza T, Rubartelli A, Figini M, Canevari S, Ferrini S.

Oncogene. 2004 Sep 30;23(45):7552-60.

PMID:
15326478
3.

Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta.

Seki E, Tsutsui H, Nakano H, Tsuji N, Hoshino K, Adachi O, Adachi K, Futatsugi S, Kuida K, Takeuchi O, Okamura H, Fujimoto J, Akira S, Nakanishi K.

J Immunol. 2001 Feb 15;166(4):2651-7.

4.

Processing and activation of pro-interleukin-16 by caspase-3.

Zhang Y, Center DM, Wu DM, Cruikshank WW, Yuan J, Andrews DW, Kornfeld H.

J Biol Chem. 1998 Jan 9;273(2):1144-9.

5.

Production of a biologically active human interleukin 18 requires its prior synthesis as PRO-IL-18.

Liu B, Novick D, Kim SH, Rubinstein M.

Cytokine. 2000 Oct;12(10):1519-25.

PMID:
11023667
6.

Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor.

Verhoef PA, Kertesy SB, Lundberg K, Kahlenberg JM, Dubyak GR.

J Immunol. 2005 Dec 1;175(11):7623-34.

7.

Neutrophils process interleukin-1beta and interleukin-18 precursors in a caspase-1-like fashion--processing is inhibited by human vascular smooth muscle cells.

Westphal E, Herzberg M, Neumann I, Beibei L, Pilowski C, Li C, Werdan K, Loppnow H.

Eur Cytokine Netw. 2006 Mar;17(1):19-28.

8.

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8.

Maelfait J, Vercammen E, Janssens S, Schotte P, Haegman M, Magez S, Beyaert R.

J Exp Med. 2008 Sep 1;205(9):1967-73. doi: 10.1084/jem.20071632. Epub 2008 Aug 25.

9.

Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes.

Massonnet B, Normand S, Moschitz R, Delwail A, Favot L, Garcia M, Bourmeyster N, Cuisset L, Grateau G, Morel F, Silvain C, Lecron JC.

Eur Cytokine Netw. 2009 Sep;20(3):112-20. doi: 10.1684/ecn.2009.0162.

10.

Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1.

Kuijk LM, Mandey SH, Schellens I, Waterham HR, Rijkers GT, Coffer PJ, Frenkel J.

Mol Immunol. 2008 Apr;45(8):2158-65. doi: 10.1016/j.molimm.2007.12.008. Epub 2008 Feb 1.

PMID:
18242710
11.

Temporal interleukin-1beta secretion from primary human peripheral blood monocytes by P2X7-independent and P2X7-dependent mechanisms.

Ward JR, West PW, Ariaans MP, Parker LC, Francis SE, Crossman DC, Sabroe I, Wilson HL.

J Biol Chem. 2010 Jul 23;285(30):23147-58. doi: 10.1074/jbc.M109.072793. Epub 2010 May 21.

12.

The activation of P2X7 receptor induces cathepsin D-dependent production of a 20-kDa form of IL-1β under acidic extracellular pH in LPS-primed microglial cells.

Takenouchi T, Iwamaru Y, Sugama S, Tsukimoto M, Fujita M, Sekigawa A, Sekiyama K, Sato M, Kojima S, Conti B, Hashimoto M, Kitani H.

J Neurochem. 2011 May;117(4):712-23. doi: 10.1111/j.1471-4159.2011.07240.x. Epub 2011 Mar 28.

13.

Maturation and release of interleukin-1beta by lipopolysaccharide-primed mouse Schwann cells require the stimulation of P2X7 receptors.

Colomar A, Marty V, Médina C, Combe C, Parnet P, Amédée T.

J Biol Chem. 2003 Aug 15;278(33):30732-40. Epub 2003 Jun 9.

14.

TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells.

Hurst J, Prinz N, Lorenz M, Bauer S, Chapman J, Lackner KJ, von Landenberg P.

Immunobiology. 2009;214(8):683-91. doi: 10.1016/j.imbio.2008.12.003. Epub 2009 Feb 26.

PMID:
19249118
15.

Mature interleukin-33 is produced by calpain-mediated cleavage in vivo.

Hayakawa M, Hayakawa H, Matsuyama Y, Tamemoto H, Okazaki H, Tominaga S.

Biochem Biophys Res Commun. 2009 Sep 11;387(1):218-22. doi: 10.1016/j.bbrc.2009.07.018. Epub 2009 Jul 9.

PMID:
19596270
16.

Involvement of cathepsin B in the processing and secretion of interleukin-1beta in chromogranin A-stimulated microglia.

Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H.

Glia. 2010 Jan 1;58(1):114-24. doi: 10.1002/glia.20906.

PMID:
19544382
17.

Rat microglial cells secrete predominantly the precursor of interleukin-1beta in response to lipopolysaccharide.

Chauvet N, Palin K, Verrier D, Poole S, Dantzer R, Lestage J.

Eur J Neurosci. 2001 Aug;14(4):609-17.

PMID:
11556886
18.

Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production.

Le Feuvre RA, Brough D, Iwakura Y, Takeda K, Rothwell NJ.

J Biol Chem. 2002 Feb 1;277(5):3210-8. Epub 2001 Nov 12.

19.

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage.

Pelegrin P, Barroso-Gutierrez C, Surprenant A.

J Immunol. 2008 Jun 1;180(11):7147-57.

20.

Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.

Schumann RR, Belka C, Reuter D, Lamping N, Kirschning CJ, Weber JR, Pfeil D.

Blood. 1998 Jan 15;91(2):577-84.

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