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Items: 1 to 20 of 101

1.

Neurokinin 1 receptor isoforms and the control of innate immunity.

Tuluc F, Lai JP, Kilpatrick LE, Evans DL, Douglas SD.

Trends Immunol. 2009 Jun;30(6):271-6. doi: 10.1016/j.it.2009.03.006. Epub 2009 May 7. Review.

PMID:
19427266
2.

Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation.

Douglas SD, Leeman SE.

Ann N Y Acad Sci. 2011 Jan;1217:83-95. doi: 10.1111/j.1749-6632.2010.05826.x. Epub 2010 Nov 22. Review.

3.

Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R).

Chernova I, Lai JP, Li H, Schwartz L, Tuluc F, Korchak HM, Douglas SD, Kilpatrick LE.

J Leukoc Biol. 2009 Jan;85(1):154-64. doi: 10.1189/jlb.0408260. Epub 2008 Oct 3.

4.

Expression of substance P, neurokinin-1 receptor and immune markers in the brains of individuals with HIV-associated neuropathology.

Spitsin S, Stevens KE, Douglas SD.

J Neurol Sci. 2013 Nov 15;334(1-2):18-23. doi: 10.1016/j.jns.2013.07.008. Epub 2013 Aug 2.

5.

Neurokinin-1 receptor expression and function in human macrophages and brain: perspective on the role in HIV neuropathogenesis.

Douglas SD, Lai JP, Tuluc F, Schwartz L, Kilpatrick LE.

Ann N Y Acad Sci. 2008 Nov;1144:90-6. doi: 10.1196/annals.1418.007.

PMID:
19076368
6.

Differences in the length of the carboxyl terminus mediate functional properties of neurokinin-1 receptor.

Lai JP, Lai S, Tuluc F, Tansky MF, Kilpatrick LE, Leeman SE, Douglas SD.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12605-10. doi: 10.1073/pnas.0806632105. Epub 2008 Aug 19.

7.

Neurokinin 1 receptor signaling affects the local innate immune defense against genital herpes virus infection.

Svensson A, Kaim J, Mallard C, Olsson A, Brodin E, Hökfelt T, Eriksson K.

J Immunol. 2005 Nov 15;175(10):6802-11.

8.

Hepatoblastoma cells express truncated neurokinin-1 receptor and can be growth inhibited by aprepitant in vitro and in vivo.

Berger M, Neth O, Ilmer M, Garnier A, Salinas-Martín MV, de Agustín Asencio JC, von Schweinitz D, Kappler R, Muñoz M.

J Hepatol. 2014 May;60(5):985-94. doi: 10.1016/j.jhep.2013.12.024. Epub 2014 Jan 8.

PMID:
24412605
9.

Substance P and neurokinin-1 receptor modulation of HIV.

Ho WZ, Douglas SD.

J Neuroimmunol. 2004 Dec;157(1-2):48-55. Review.

PMID:
15579279
10.

Expression of different neurokinin-1 receptor (NK1R) isoforms in glioblastoma multiforme: potential implications for targeted therapy.

Cordier D, Gerber A, Kluba C, Bauman A, Hutter G, Mindt TL, Mariani L.

Cancer Biother Radiopharm. 2014 Jun;29(5):221-6. doi: 10.1089/cbr.2013.1588. Epub 2014 Feb 19.

PMID:
24552486
11.

Detection of the full-length transcript variant for neurokinin-1 receptor in human whole blood associated with enhanced reinforcement of clot by substance-P.

Azma T, Sugimoto Y, Kinoshita H, Ito T, Tsukamoto M, Hoshijima H, Nakao M, Kikuchi H.

J Thromb Thrombolysis. 2012 May;33(4):329-37. doi: 10.1007/s11239-011-0650-1.

PMID:
22057425
12.

Roles of full-length and truncated neurokinin-1 receptors on tumor progression and distant metastasis in human breast cancer.

Zhou Y, Zhao L, Xiong T, Chen X, Zhang Y, Yu M, Yang J, Yao Z.

Breast Cancer Res Treat. 2013 Jul;140(1):49-61. doi: 10.1007/s10549-013-2599-6. Epub 2013 Jun 27.

PMID:
23807418
14.

Altered expression of the tachykinins substance P/neurokinin A/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 receptors in uterine leiomyomata.

González-Santana A, Marrero-Hernández S, Dorta I, Hernández M, Pinto FM, Báez D, Bello AR, Candenas L, Almeida TA.

Fertil Steril. 2016 Nov;106(6):1521-1529. doi: 10.1016/j.fertnstert.2016.07.007. Epub 2016 Jul 25.

PMID:
27456549
15.

Neurokinin-1 receptor mRNA expression differences in brains of HIV-infected individuals.

Douglas SD, Lynch KG, Lai JP.

J Neurol Sci. 2008 Sep 15;272(1-2):174-7. doi: 10.1016/j.jns.2008.04.025. Epub 2008 Jun 24.

16.

Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor.

Spitsin S, Tuluc F, Meshki J, Ping Lai J, Tustin Iii R, Douglas SD.

Neuroimmunomodulation. 2013;20(5):247-55. doi: 10.1159/000350468. Epub 2013 Jul 5.

17.

Anti-HIV-1 activity of the neurokinin-1 receptor antagonist aprepitant and synergistic interactions with other antiretrovirals.

Manak MM, Moshkoff DA, Nguyen LT, Meshki J, Tebas P, Tuluc F, Douglas SD.

AIDS. 2010 Nov 27;24(18):2789-96. doi: 10.1097/QAD.0b013e3283405c33.

18.

Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury.

Bhatia M, Saluja AK, Hofbauer B, Frossard JL, Lee HS, Castagliuolo I, Wang CC, Gerard N, Pothoulakis C, Steer ML.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4760-5.

19.

Proinflammatory tachykinins that signal through the neurokinin 1 receptor promote survival of dendritic cells and potent cellular immunity.

Janelsins BM, Mathers AR, Tkacheva OA, Erdos G, Shufesky WJ, Morelli AE, Larregina AT.

Blood. 2009 Mar 26;113(13):3017-26. doi: 10.1182/blood-2008-06-163121. Epub 2008 Nov 5.

20.

The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.

Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M.

J Immunol. 2008 Jun 15;180(12):8333-41.

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