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Items: 1 to 20 of 72

1.

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, Strachan DP, Wilk JB, Willis-Owen SA, Klanderman B, Lasky-Su J, Lazarus R, Murphy AJ, Soto-Quiros ME, Avila L, Beaty T, Mathias RA, Ruczinski I, Barnes KC, Celedón JC, Cookson WO, Gauderman WJ, Gilliland FD, Hakonarson H, Lange C, Moffatt MF, O'Connor GT, Raby BA, Silverman EK, Weiss ST.

Am J Hum Genet. 2009 May;84(5):581-93. doi: 10.1016/j.ajhg.2009.04.006. Epub 2009 May 7.

2.

Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.

Ding L, Abebe T, Beyene J, Wilke RA, Goldberg A, Woo JG, Martin LJ, Rothenberg ME, Rao M, Hershey GK, Chakraborty R, Mersha TB.

Hum Genomics. 2013 Jul 5;7:16. doi: 10.1186/1479-7364-7-16.

3.

Aberrant DNA Methylation of Phosphodiesterase [corrected] 4D Alters Airway Smooth Muscle Cell Phenotypes.

Lin AH, Shang Y, Mitzner W, Sham JS, Tang WY.

Am J Respir Cell Mol Biol. 2016 Feb;54(2):241-9. doi: 10.1165/rcmb.2015-0079OC. Erratum in: Am J Respir Cell Mol Biol. 2016 Apr;54(4):597.

4.

Polymorphisms in PDE4D are associated with a risk of COPD in non-emphysematous Koreans.

Yoon HK, Hu HJ, Rhee CK, Shin SH, Oh YM, Lee SD, Jung SH, Yim SH, Kim TM; Korean Obstructive Lung Disease (KOLD) Study Group, Chung YJ.

COPD. 2014 Dec;11(6):652-8. doi: 10.3109/15412555.2014.898045. Epub 2014 Jun 13.

PMID:
24926854
5.

Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

Ferreira MA, McRae AF, Medland SE, Nyholt DR, Gordon SD, Wright MJ, Henders AK, Madden PA, Visscher PM, Wray NR, Heath AC, Montgomery GW, Duffy DL, Martin NG.

Eur J Hum Genet. 2011 Apr;19(4):458-64. doi: 10.1038/ejhg.2010.191. Epub 2010 Dec 8. Erratum in: Eur J Hum Genet. 2011 Oct;19(10):1109.

6.

Genome-wide association study of the age of onset of childhood asthma.

Forno E, Lasky-Su J, Himes B, Howrylak J, Ramsey C, Brehm J, Klanderman B, Ziniti J, Melén E, Pershagen G, Wickman M, Martinez F, Mauger D, Sorkness C, Tantisira K, Raby BA, Weiss ST, Celedón JC.

J Allergy Clin Immunol. 2012 Jul;130(1):83-90.e4. doi: 10.1016/j.jaci.2012.03.020. Epub 2012 May 2.

7.

Linkage of ischemic stroke to the PDE4D region on 5q in a Swedish population.

Nilsson-Ardnor S, Wiklund PG, Lindgren P, Nilsson AK, Janunger T, Escher SA, Hallbeck B, Stegmayr B, Asplund K, Holmberg D.

Stroke. 2005 Aug;36(8):1666-71. Epub 2005 Jul 14.

8.

Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.

Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E; SHARP Investigators.

Am J Respir Crit Care Med. 2012 Jun 15;185(12):1286-91. doi: 10.1164/rccm.201111-2061OC. Epub 2012 Apr 26.

9.

Phosphodiesterase 4D gene and risk of noncardiogenic ischemic stroke in a Korean population.

Kim MK, Kim JT, Choi SM, Lee SH, Park MS, Cho KH.

J Korean Med Sci. 2009 Apr;24(2):307-10. doi: 10.3346/jkms.2009.24.2.307. Epub 2009 Apr 20.

10.

[Association of Polymorphic Variants of Gene MUC19 with Asthma in Russians According to the Results of a Genome-Wide Study].

Karunas AS, Yunusbaev BB, Fedorova YY, Gimalova GF, Khusnutdinova EK.

Genetika. 2015 Nov;51(11):1315-24. Russian.

PMID:
26845862
11.

[Genome-wide association study of bronchial asthma in the Volga-Ural region of Russia].

Karunas AS, Iunusbaev BB, Fedorova IuIu, Gimalova GF, Ramazanova NN, Gur'eva LL, Mukhtarova LA, Zagidullin ShZ, Etkina EI, Khusnutdinova EK.

Mol Biol (Mosk). 2011 Nov-Dec;45(6):992-1003. Russian.

PMID:
22295569
12.

Asthma susceptibility variants are more strongly associated with clinically similar subgroups.

Lavoie-Charland E, Bérubé JC, Boulet LP, Bossé Y.

J Asthma. 2016 Nov;53(9):907-13. doi: 10.3109/02770903.2016.1165699. Epub 2016 Apr 8.

PMID:
27058054
13.

Analyses of shared genetic factors between asthma and obesity in children.

Melén E, Himes BE, Brehm JM, Boutaoui N, Klanderman BJ, Sylvia JS, Lasky-Su J.

J Allergy Clin Immunol. 2010 Sep;126(3):631-7.e1-8. doi: 10.1016/j.jaci.2010.06.030.

14.

Phosphodiesterase type 4D gene polymorphism: association with the response to short-acting bronchodilators in paediatric asthma patients.

Labuda M, Laberge S, Brière J, Bérubé D, Beaulieu P, Pastinen T, Krajinovic M.

Mediators Inflamm. 2011;2011:301695. doi: 10.1155/2011/301695. Epub 2011 Aug 24.

15.

Association of phosphodiesterase 4D gene polymorphisms with chronic obstructive pulmonary disease: relationship to interleukin 13 gene polymorphism.

Homma S, Sakamoto T, Hegab AE, Saitoh W, Nomura A, Ishii Y, Morishima Y, Iizuka T, Kiwamoto T, Matsuno Y, Massoud HH, Massoud HM, Hassanein KM, Sekizawa K.

Int J Mol Med. 2006 Nov;18(5):933-9.

PMID:
17016624
16.

Polymorphisms of the phosphodiesterase 4D, cAMP-specific (PDE4D) gene and risk of ischemic stroke: a prospective, nested case-control evaluation.

Zee RY, Brophy VH, Cheng S, Hegener HH, Erlich HA, Ridker PM.

Stroke. 2006 Aug;37(8):2012-7. Epub 2006 Jul 6.

17.

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Fölster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Söderhäll C, Melén E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF.

Hum Mol Genet. 2013 Dec 1;22(23):4841-56. doi: 10.1093/hmg/ddt317. Epub 2013 Jul 25.

18.

Genomewide association study identifies HAS2 as a novel susceptibility gene for adult asthma in a Japanese population.

Yatagai Y, Sakamoto T, Yamada H, Masuko H, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Konno S, Nishimura M, Hizawa N.

Clin Exp Allergy. 2014 Nov;44(11):1327-34. doi: 10.1111/cea.12415.

PMID:
25251750
19.

Phosphodiesterase4D (PDE4D)--A risk factor for atrial fibrillation and stroke?

Jørgensen C, Yasmeen S, Iversen HK, Kruuse C.

J Neurol Sci. 2015 Dec 15;359(1-2):266-74. doi: 10.1016/j.jns.2015.11.010. Epub 2015 Nov 11. Review.

PMID:
26671126
20.

Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma.

Deng YM, Xie QM, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY.

Eur J Pharmacol. 2006 Oct 10;547(1-3):125-35. Epub 2006 Jul 13.

PMID:
16956605

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