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Items: 1 to 20 of 137

1.

Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice.

Yang ES, Wang H, Jiang G, Nowsheen S, Fu A, Hallahan DE, Xia F.

J Clin Invest. 2009 May;119(5):1124-35.

2.

Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons.

Yang ES, Nowsheen S, Wang T, Thotala DK, Xia F.

Neuro Oncol. 2011 May;13(5):459-70. doi: 10.1093/neuonc/nor016. Epub 2011 Mar 11.

3.

DNA-PK promotes the survival of young neurons in the embryonic mouse retina.

Baleriola J, Suárez T, de la Rosa EJ.

Cell Death Differ. 2010 Nov;17(11):1697-706. doi: 10.1038/cdd.2010.46. Epub 2010 May 7.

4.

Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells.

Klammer H, Kadhim M, Iliakis G.

Cancer Res. 2010 Nov 1;70(21):8498-506. doi: 10.1158/0008-5472.CAN-10-1181. Epub 2010 Sep 22.

5.

DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells.

Urushihara Y, Kobayashi J, Matsumoto Y, Komatsu K, Oda S, Mitani H.

Biochem Biophys Res Commun. 2012 Dec 14;429(3-4):131-6. doi: 10.1016/j.bbrc.2012.10.128. Epub 2012 Nov 7.

PMID:
23142596
7.

Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.

Inturi S, Tewari-Singh N, Agarwal C, White CW, Agarwal R.

Mutat Res. 2014 May-Jun;763-764:53-63. doi: 10.1016/j.mrfmmm.2014.04.002. Epub 2014 Apr 13.

8.

Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.

Wang H, Zeng ZC, Bui TA, DiBiase SJ, Qin W, Xia F, Powell SN, Iliakis G.

Cancer Res. 2001 Jan 1;61(1):270-7.

9.

Parp1-XRCC1 and the repair of DNA double strand breaks in mouse round spermatids.

Ahmed EA, de Boer P, Philippens ME, Kal HB, de Rooij DG.

Mutat Res. 2010 Jan 5;683(1-2):84-90. doi: 10.1016/j.mrfmmm.2009.10.011.

PMID:
19887075
10.

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

Douglas P, Zhong J, Ye R, Moorhead GB, Xu X, Lees-Miller SP.

Mol Cell Biol. 2010 Mar;30(6):1368-81. doi: 10.1128/MCB.00741-09. Epub 2010 Jan 11.

11.

The kinase activity of DNA-PK is required to protect mammalian telomeres.

Bailey SM, Brenneman MA, Halbrook J, Nickoloff JA, Ullrich RL, Goodwin EH.

DNA Repair (Amst). 2004 Mar 4;3(3):225-33.

PMID:
15177038
12.

Lead contamination results in late and slowly repairable DNA double-strand breaks and impacts upon the ATM-dependent signaling pathways.

Gastaldo J, Viau M, Bencokova Z, Joubert A, Charvet AM, Balosso J, Foray N.

Toxicol Lett. 2007 Sep 28;173(3):201-14. Epub 2007 Aug 11.

PMID:
17855027
13.

Backup pathways of NHEJ are suppressed by DNA-PK.

Perrault R, Wang H, Wang M, Rosidi B, Iliakis G.

J Cell Biochem. 2004 Jul 1;92(4):781-94.

PMID:
15211575
14.

Inhibition of DNA-dependent protein kinase induces accelerated senescence in irradiated human cancer cells.

Azad A, Jackson S, Cullinane C, Natoli A, Neilsen PM, Callen DF, Maira SM, Hackl W, McArthur GA, Solomon B.

Mol Cancer Res. 2011 Dec;9(12):1696-707. doi: 10.1158/1541-7786.MCR-11-0312. Epub 2011 Oct 18.

15.

Gefitinib radiosensitizes stem-like glioma cells: inhibition of epidermal growth factor receptor-Akt-DNA-PK signaling, accompanied by inhibition of DNA double-strand break repair.

Kang KB, Zhu C, Wong YL, Gao Q, Ty A, Wong MC.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):e43-52. doi: 10.1016/j.ijrobp.2011.11.037.

PMID:
22516386
16.

Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination.

Tavecchio M, Munck JM, Cano C, Newell DR, Curtin NJ.

Cancer Chemother Pharmacol. 2012 Jan;69(1):155-64. doi: 10.1007/s00280-011-1662-4. Epub 2011 Jun 1.

PMID:
21630086
17.
18.

DNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts.

Ahmed EA, Vélaz E, Rosemann M, Gilbertz KP, Scherthan H.

Chromosoma. 2017 Mar;126(2):287-298. doi: 10.1007/s00412-016-0590-9. Epub 2016 May 2.

19.

Tissue-specific DNA-PK-dependent H2AX phosphorylation and gamma-H2AX elimination after X-irradiation in vivo.

Koike M, Sugasawa J, Yasuda M, Koike A.

Biochem Biophys Res Commun. 2008 Nov 7;376(1):52-5. doi: 10.1016/j.bbrc.2008.08.095. Epub 2008 Aug 26.

PMID:
18755145
20.

DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus.

DiBiase SJ, Zeng ZC, Chen R, Hyslop T, Curran WJ Jr, Iliakis G.

Cancer Res. 2000 Mar 1;60(5):1245-53.

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