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Items: 1 to 20 of 301

1.

In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate.

Hu S, Chen AP, Zierhut ML, Bok R, Yen YF, Schroeder MA, Hurd RE, Nelson SJ, Kurhanewicz J, Vigneron DB.

Mol Imaging Biol. 2009 Nov-Dec;11(6):399-407. doi: 10.1007/s11307-009-0218-z. Epub 2009 May 8.

2.

Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies.

Chen AP, Kurhanewicz J, Bok R, Xu D, Joun D, Zhang V, Nelson SJ, Hurd RE, Vigneron DB.

Magn Reson Imaging. 2008 Jul;26(6):721-6. doi: 10.1016/j.mri.2008.01.002. Epub 2008 May 13.

3.

In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine.

Hu S, Zhu M, Yoshihara HA, Wilson DM, Keshari KR, Shin P, Reed G, von Morze C, Bok R, Larson PE, Kurhanewicz J, Vigneron DB.

Magn Reson Imaging. 2011 Oct;29(8):1035-40. doi: 10.1016/j.mri.2011.07.001. Epub 2011 Aug 19.

4.

Rapid sequential injections of hyperpolarized [1-¹³C]pyruvate in vivo using a sub-kelvin, multi-sample DNP polarizer.

Hu S, Larson PE, Vancriekinge M, Leach AM, Park I, Leon C, Zhou J, Shin PJ, Reed G, Keselman P, von Morze C, Yoshihara H, Bok RA, Nelson SJ, Kurhanewicz J, Vigneron DB.

Magn Reson Imaging. 2013 May;31(4):490-6. doi: 10.1016/j.mri.2012.09.002. Epub 2012 Oct 27.

5.

Metabolism of hyperpolarized [1-(13)C]pyruvate through alternate pathways in rat liver.

Jin ES, Moreno KX, Wang JX, Fidelino L, Merritt ME, Sherry AD, Malloy CR.

NMR Biomed. 2016 Apr;29(4):466-74. doi: 10.1002/nbm.3479. Epub 2016 Feb 2.

6.

Quantification of in vivo metabolic kinetics of hyperpolarized pyruvate in rat kidneys using dynamic 13C MRSI.

Xu T, Mayer D, Gu M, Yen YF, Josan S, Tropp J, Pfefferbaum A, Hurd R, Spielman D.

NMR Biomed. 2011 Oct;24(8):997-1005. doi: 10.1002/nbm.1719. Epub 2011 Apr 28.

7.

In vivo 13C spectroscopy in the rat brain using hyperpolarized [1-(13)C]pyruvate and [2-(13)C]pyruvate.

Marjańska M, Iltis I, Shestov AA, Deelchand DK, Nelson C, Uğurbil K, Henry PG.

J Magn Reson. 2010 Oct;206(2):210-8. doi: 10.1016/j.jmr.2010.07.006. Epub 2010 Jul 16.

8.

Using [1-(13) C]lactic acid for hyperpolarized (13) C MR cardiac studies.

Chen AP, Lau JY, Alvares RD, Cunningham CH.

Magn Reson Med. 2015 Jun;73(6):2087-93. doi: 10.1002/mrm.25354. Epub 2014 Jul 9.

PMID:
25046652
9.

In vivo 13 carbon metabolic imaging at 3T with hyperpolarized 13C-1-pyruvate.

Kohler SJ, Yen Y, Wolber J, Chen AP, Albers MJ, Bok R, Zhang V, Tropp J, Nelson S, Vigneron DB, Kurhanewicz J, Hurd RE.

Magn Reson Med. 2007 Jul;58(1):65-9.

10.

In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma.

Darpolor MM, Yen YF, Chua MS, Xing L, Clarke-Katzenberg RH, Shi W, Mayer D, Josan S, Hurd RE, Pfefferbaum A, Senadheera L, So S, Hofmann LV, Glazer GM, Spielman DM.

NMR Biomed. 2011 Jun;24(5):506-13. doi: 10.1002/nbm.1616. Epub 2010 Dec 12.

11.

Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain.

Park I, Larson PE, Tropp JL, Carvajal L, Reed G, Bok R, Robb F, Bringas J, Kells A, Pivirotto P, Bankiewicz K, Vigneron DB, Nelson SJ.

Magn Reson Med. 2014 Jan;71(1):19-25. doi: 10.1002/mrm.25003. Epub 2013 Nov 11.

12.

Metabolic biomarkers for non-alcoholic fatty liver disease induced by high-fat diet: In vivo magnetic resonance spectroscopy of hyperpolarized [1-13C] pyruvate.

Moon CM, Oh CH, Ahn KY, Yang JS, Kim JY, Shin SS, Lim HS, Heo SH, Seon HJ, Kim JW, Jeong GW.

Biochem Biophys Res Commun. 2017 Jan 1;482(1):112-119. doi: 10.1016/j.bbrc.2016.08.118. Epub 2016 Aug 22.

PMID:
27562716
13.

Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13 C-lactate and 13 C-pyruvate in kidney and liver.

von Morze C, Chang GY, Larson PE, Shang H, Allu PK, Bok RA, Crane JC, Olson MP, Tan CT, Marco-Rius I, Nelson SJ, Kurhanewicz J, Pearce D, Vigneron DB.

Magn Reson Med. 2017 Apr;77(4):1429-1437. doi: 10.1002/mrm.26245. Epub 2016 Apr 21.

14.

Effects of pyruvate dose on in vivo metabolism and quantification of hyperpolarized ¹³C spectra.

Janich MA, Menzel MI, Wiesinger F, Weidl E, Khegai O, Ardenkjaer-Larsen JH, Glaser SJ, Haase A, Schulte RF, Schwaiger M.

NMR Biomed. 2012 Jan;25(1):142-51. doi: 10.1002/nbm.1726. Epub 2011 Aug 8.

PMID:
21823181
15.

Noninvasive biomarkers for acute hepatotoxicity induced by 1,3-dichloro-2-propanol: hyperpolarized 13C dynamic MR spectroscopy.

Kim GW, Oh CH, Kim JC, Yoon W, Jeong YY, Kim YH, Kim JK, Park JG, Kang HK, Jeong GW.

Magn Reson Imaging. 2016 Feb;34(2):159-65. doi: 10.1016/j.mri.2015.10.023. Epub 2015 Oct 30.

PMID:
26523652
16.

In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1-13 C]Alanine.

Park JM, Khemtong C, Liu SC, Hurd RE, Spielman DM.

Magn Reson Med. 2017 May;77(5):1741-1748. doi: 10.1002/mrm.26662. Epub 2017 Mar 5.

PMID:
28261868
17.

Multimodal assessment of in vivo metabolism with hyperpolarized [1-13C]MR spectroscopy and 18F-FDG PET imaging in hepatocellular carcinoma tumor-bearing rats.

Menzel MI, Farrell EV, Janich MA, Khegai O, Wiesinger F, Nekolla S, Otto AM, Haase A, Schulte RF, Schwaiger M.

J Nucl Med. 2013 Jul;54(7):1113-9. doi: 10.2967/jnumed.112.110825. Epub 2013 Apr 17.

18.

Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring.

Chaumeil MM, Radoul M, Najac C, Eriksson P, Viswanath P, Blough MD, Chesnelong C, Luchman HA, Cairncross JG, Ronen SM.

Neuroimage Clin. 2016 Jun 23;12:180-9. doi: 10.1016/j.nicl.2016.06.018. eCollection 2016.

19.

In vivo measurement of aldehyde dehydrogenase-2 activity in rat liver ethanol model using dynamic MRSI of hyperpolarized [1-(13) C]pyruvate.

Josan S, Xu T, Yen YF, Hurd R, Ferreira J, Chen CH, Mochly-Rosen D, Pfefferbaum A, Mayer D, Spielman D.

NMR Biomed. 2013 Jun;26(6):607-12. doi: 10.1002/nbm.2897. Epub 2012 Dec 6.

20.

T(2) relaxation times of (13)C metabolites in a rat hepatocellular carcinoma model measured in vivo using (13)C-MRS of hyperpolarized [1-(13)C]pyruvate.

Yen YF, Le Roux P, Mayer D, King R, Spielman D, Tropp J, Butts Pauly K, Pfefferbaum A, Vasanawala S, Hurd R.

NMR Biomed. 2010 May;23(4):414-23. doi: 10.1002/nbm.1481. Epub 2010 Feb 19.

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