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Items: 1 to 20 of 110

1.

Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.

Benedikt J, Samad A, Ettrich R, Teisinger J, Vlachova V.

Biochim Biophys Acta. 2009 Jul;1793(7):1279-88. doi: 10.1016/j.bbamcr.2009.04.014. Epub 2009 May 5.

2.

Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state.

Zíma V, Witschas K, Hynkova A, Zímová L, Barvík I, Vlachova V.

Neuropharmacology. 2015 Jun;93:294-307. doi: 10.1016/j.neuropharm.2015.02.018. Epub 2015 Feb 25.

PMID:
25724085
3.

Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells.

Louhivuori LM, Bart G, Larsson KP, Louhivuori V, Näsman J, Nordström T, Koivisto AP, Akerman KE.

J Cell Physiol. 2009 Oct;221(1):67-74. doi: 10.1002/jcp.21828.

PMID:
19507192
4.

The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1.

Samad A, Sura L, Benedikt J, Ettrich R, Minofar B, Teisinger J, Vlachova V.

Biochem J. 2011 Jan 1;433(1):197-204. doi: 10.1042/BJ20101256.

5.

Irritating channels: the case of TRPA1.

Nilius B, Prenen J, Owsianik G.

J Physiol. 2011 Apr 1;589(Pt 7):1543-9. doi: 10.1113/jphysiol.2010.200717. Epub 2010 Nov 15. Review.

6.

Molecular determinants of species-specific activation or blockade of TRPA1 channels.

Chen J, Zhang XF, Kort ME, Huth JR, Sun C, Miesbauer LJ, Cassar SC, Neelands T, Scott VE, Moreland RB, Reilly RM, Hajduk PJ, Kym PR, Hutchins CW, Faltynek CR.

J Neurosci. 2008 May 7;28(19):5063-71. doi: 10.1523/JNEUROSCI.0047-08.2008.

7.

Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative.

Yassaka RT, Inagaki H, Fujino T, Nakatani K, Kubo T.

Neurosci Res. 2010 Jan;66(1):99-105. doi: 10.1016/j.neures.2009.09.1712. Epub 2009 Oct 4.

PMID:
19808063
8.

Transient receptor potential channel A1 is directly gated by calcium ions.

Doerner JF, Gisselmann G, Hatt H, Wetzel CH.

J Biol Chem. 2007 May 4;282(18):13180-9. Epub 2007 Mar 12.

9.

Pore dilation occurs in TRPA1 but not in TRPM8 channels.

Chen J, Kim D, Bianchi BR, Cavanaugh EJ, Faltynek CR, Kym PR, Reilly RM.

Mol Pain. 2009 Jan 21;5:3. doi: 10.1186/1744-8069-5-3.

10.

Heat and AITC activate green anole TRPA1 in a membrane-delimited manner.

Kurganov E, Zhou Y, Saito S, Tominaga M.

Pflugers Arch. 2014 Oct;466(10):1873-84. doi: 10.1007/s00424-013-1420-z. Epub 2014 Jan 3.

PMID:
24385018
11.

The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings.

Bobkov YV, Corey EA, Ache BW.

Biochim Biophys Acta. 2011 Apr;1808(4):1120-8. doi: 10.1016/j.bbamem.2010.12.024. Epub 2010 Dec 29.

12.

The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression.

Nagatomo K, Ishii H, Yamamoto T, Nakajo K, Kubo Y.

Biophys J. 2010 Dec 1;99(11):3609-18. doi: 10.1016/j.bpj.2010.10.014.

13.

QGP-1 cells release 5-HT via TRPA1 activation; a model of human enterochromaffin cells.

Doihara H, Nozawa K, Kojima R, Kawabata-Shoda E, Yokoyama T, Ito H.

Mol Cell Biochem. 2009 Nov;331(1-2):239-45. doi: 10.1007/s11010-009-0165-7. Epub 2009 Jun 9.

PMID:
19507004
14.

Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells.

Büch TR, Schäfer EA, Demmel MT, Boekhoff I, Thiermann H, Gudermann T, Steinritz D, Schmidt A.

Chem Biol Interact. 2013 Dec 5;206(3):462-71. doi: 10.1016/j.cbi.2013.08.012. Epub 2013 Aug 30.

PMID:
23994502
15.

Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation.

Banke TG, Chaplan SR, Wickenden AD.

Am J Physiol Cell Physiol. 2010 Jun;298(6):C1457-68. doi: 10.1152/ajpcell.00489.2009. Epub 2010 Mar 24.

16.

Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.

Mukhopadhyay I, Gomes P, Aranake S, Shetty M, Karnik P, Damle M, Kuruganti S, Thorat S, Khairatkar-Joshi N.

J Recept Signal Transduct Res. 2011 Oct;31(5):350-8. doi: 10.3109/10799893.2011.602413. Epub 2011 Aug 17.

PMID:
21848366
17.

Activation of transient receptor potential ankyrin 1 by eugenol.

Chung G, Im ST, Kim YH, Jung SJ, Rhyu MR, Oh SB.

Neuroscience. 2014 Mar 7;261:153-60. doi: 10.1016/j.neuroscience.2013.12.047. Epub 2013 Dec 30.

PMID:
24384226
18.

Species differences and molecular determinant of TRPA1 cold sensitivity.

Chen J, Kang D, Xu J, Lake M, Hogan JO, Sun C, Walter K, Yao B, Kim D.

Nat Commun. 2013;4:2501. doi: 10.1038/ncomms3501.

19.

Activation of TRPA1 by farnesyl thiosalicylic acid.

Maher M, Ao H, Banke T, Nasser N, Wu NT, Breitenbucher JG, Chaplan SR, Wickenden AD.

Mol Pharmacol. 2008 Apr;73(4):1225-34. doi: 10.1124/mol.107.042663. Epub 2008 Jan 2.

20.

Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful?

Boukalova S, Touska F, Marsakova L, Hynkova A, Sura L, Chvojka S, Dittert I, Vlachova V.

Physiol Res. 2014;63 Suppl 1:S205-13. Review. Erratum in: Physiol Res. 2014;63(5):667.

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