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Items: 1 to 20 of 90


Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases lambda and mu for nonhomologous end joining in human whole-cell extracts.

Akopiants K, Zhou RZ, Mohapatra S, Valerie K, Lees-Miller SP, Lee KJ, Chen DJ, Revy P, de Villartay JP, Povirk LF.

Nucleic Acids Res. 2009 Jul;37(12):4055-62. doi: 10.1093/nar/gkp283. Epub 2009 May 6.


Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.

Lee JW, Blanco L, Zhou T, Garcia-Diaz M, Bebenek K, Kunkel TA, Wang Z, Povirk LF.

J Biol Chem. 2004 Jan 2;279(1):805-11. Epub 2003 Oct 15.


Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell.

Wu PY, Frit P, Malivert L, Revy P, Biard D, Salles B, Calsou P.

J Biol Chem. 2007 Nov 2;282(44):31937-43. Epub 2007 Aug 24.


DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.

Yu Y, Mahaney BL, Yano K, Ye R, Fang S, Douglas P, Chen DJ, Lees-Miller SP.

DNA Repair (Amst). 2008 Oct 1;7(10):1680-92. doi: 10.1016/j.dnarep.2008.06.015. Epub 2008 Aug 3.


Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts.

Zhou RZ, Blanco L, Garcia-Diaz M, Bebenek K, Kunkel TA, Povirk LF.

Nucleic Acids Res. 2008 May;36(9):2895-905. doi: 10.1093/nar/gkn126. Epub 2008 Apr 1.


Cernunnos/XLF: a new player in DNA double-strand break repair.

Yano K, Morotomi-Yano K, Akiyama H.

Int J Biochem Cell Biol. 2009 Jun;41(6):1237-40. doi: 10.1016/j.biocel.2008.10.005. Epub 2008 Oct 17. Review.


The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

Malivert L, Callebaut I, Rivera-Munoz P, Fischer A, Mornon JP, Revy P, de Villartay JP.

Mol Cell Biol. 2009 Mar;29(5):1116-22. doi: 10.1128/MCB.01521-08. Epub 2008 Dec 22.


Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.

Ropars V, Drevet P, Legrand P, Baconnais S, Amram J, Faure G, Márquez JA, Piétrement O, Guerois R, Callebaut I, Le Cam E, Revy P, de Villartay JP, Charbonnier JB.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12663-8. doi: 10.1073/pnas.1100758108. Epub 2011 Jul 18.


Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF.

Malivert L, Ropars V, Nunez M, Drevet P, Miron S, Faure G, Guerois R, Mornon JP, Revy P, Charbonnier JB, Callebaut I, de Villartay JP.

J Biol Chem. 2010 Aug 20;285(34):26475-83. doi: 10.1074/jbc.M110.138156. Epub 2010 Jun 17.


Role and regulation of human XRCC4-like factor/cernunnos.

Dahm K.

J Cell Biochem. 2008 Aug 1;104(5):1534-40. doi: 10.1002/jcb.21726. Review.


Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity.

Chen S, Inamdar KV, Pfeiffer P, Feldmann E, Hannah MF, Yu Y, Lee JW, Zhou T, Lees-Miller SP, Povirk LF.

J Biol Chem. 2001 Jun 29;276(26):24323-30. Epub 2001 Apr 17.


A noncatalytic function of the ligation complex during nonhomologous end joining.

Cottarel J, Frit P, Bombarde O, Salles B, Négrel A, Bernard S, Jeggo PA, Lieber MR, Modesti M, Calsou P.

J Cell Biol. 2013 Jan 21;200(2):173-86. doi: 10.1083/jcb.201203128.


XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair.

Hammel M, Rey M, Yu Y, Mani RS, Classen S, Liu M, Pique ME, Fang S, Mahaney BL, Weinfeld M, Schriemer DC, Lees-Miller SP, Tainer JA.

J Biol Chem. 2011 Sep 16;286(37):32638-50. doi: 10.1074/jbc.M111.272641. Epub 2011 Jul 20.


Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.

Zha S, Alt FW, Cheng HL, Brush JW, Li G.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4518-23. Epub 2007 Mar 7.


Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors.

Tilgner K, Neganova I, Singhapol C, Saretzki G, Al-Aama JY, Evans J, Gorbunova V, Gennery A, Przyborski S, Stojkovic M, Armstrong L, Jeggo P, Lako M.

Stem Cells. 2013 Sep;31(9):2015-23. doi: 10.1002/stem.1456.


Crystal structure of human XLF: a twist in nonhomologous DNA end-joining.

Andres SN, Modesti M, Tsai CJ, Chu G, Junop MS.

Mol Cell. 2007 Dec 28;28(6):1093-101.


Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae.

Chan CY, Galli A, Schiestl RH.

DNA Repair (Amst). 2008 Sep 1;7(9):1531-41. doi: 10.1016/j.dnarep.2008.05.008. Epub 2008 Jul 7.


Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos.

Hentges P, Ahnesorg P, Pitcher RS, Bruce CK, Kysela B, Green AJ, Bianchi J, Wilson TE, Jackson SP, Doherty AJ.

J Biol Chem. 2006 Dec 8;281(49):37517-26. Epub 2006 Oct 12.

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