Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 222

1.

Characterizing the effects of common UDP glucuronosyltransferase (UGT) 1A6 and UGT1A1 polymorphisms on cis- and trans-resveratrol glucuronidation.

Iwuchukwu OF, Ajetunmobi J, Ung D, Nagar S.

Drug Metab Dispos. 2009 Aug;37(8):1726-32. doi: 10.1124/dmd.109.027391. Epub 2009 Apr 30.

2.
3.

Cis-resveratrol glucuronidation kinetics in human and recombinant UGT1A sources.

Iwuchukwu OF, Nagar S.

Xenobiotica. 2010 Feb;40(2):102-8. doi: 10.3109/00498250903406754.

PMID:
20017604
4.
5.

Regioselective and stereospecific glucuronidation of trans- and cis-resveratrol in human.

Aumont V, Krisa S, Battaglia E, Netter P, Richard T, Mérillon JM, Magdalou J, Sabolovic N.

Arch Biochem Biophys. 2001 Sep 15;393(2):281-9.

PMID:
11556815
6.

Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin.

Hanioka N, Ozawa S, Jinno H, Ando M, Saito Y, Sawada J.

Xenobiotica. 2001 Oct;31(10):687-99.

PMID:
11695848
7.

Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.

Innocenti F, Iyer L, Ramírez J, Green MD, Ratain MJ.

Drug Metab Dispos. 2001 May;29(5):686-92.

8.
9.

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation.

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH.

J Pharmacol Exp Ther. 2005 Jun;313(3):1331-9. Epub 2005 Mar 10.

10.

Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes.

Hanioka N, Takeda Y, Jinno H, Tanaka-Kagawa T, Naito S, Koeda A, Shimizu T, Nomura M, Narimatsu S.

Chem Biol Interact. 2006 Dec 1;164(1-2):136-45. Epub 2006 Oct 9.

PMID:
17027947
11.

Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1.

Watanabe Y, Nakajima M, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2003 May;31(5):589-95.

12.

Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4.

Aprile S, Del Grosso E, Grosa G.

Drug Metab Dispos. 2010 Jul;38(7):1141-6. doi: 10.1124/dmd.109.031435. Epub 2010 Apr 7.

13.

Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.

Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2002 Jun;30(6):636-42.

14.

Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.

Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.

Drug Metab Dispos. 2008 Feb;36(2):361-7. Epub 2007 Nov 12.

15.

Raloxifene glucuronidation in human intestine, kidney, and liver microsomes and in human liver microsomes genotyped for the UGT1A1*28 polymorphism.

Trdan Lusin T, Trontelj J, Mrhar A.

Drug Metab Dispos. 2011 Dec;39(12):2347-54. doi: 10.1124/dmd.111.041897. Epub 2011 Sep 21.

16.

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank.

Fisher MB, Vandenbranden M, Findlay K, Burchell B, Thummel KE, Hall SD, Wrighton SA.

Pharmacogenetics. 2000 Nov;10(8):727-39.

PMID:
11186135
17.

Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.

Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T.

Drug Metab Dispos. 2005 Jan;33(1):23-30. Epub 2004 Oct 6.

18.

Glucuronidation of trans-resveratrol by human liver and intestinal microsomes and UGT isoforms.

Brill SS, Furimsky AM, Ho MN, Furniss MJ, Li Y, Green AG, Bradford WW, Green CE, Kapetanovic IM, Iyer LV.

J Pharm Pharmacol. 2006 Apr;58(4):469-79.

PMID:
16597364
19.

The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure.

Court MH, Freytsis M, Wang X, Peter I, Guillemette C, Hazarika S, Duan SX, Greenblatt DJ, Lee WM; Acute Liver Failure Study Group.

J Pharmacol Exp Ther. 2013 May;345(2):297-307. doi: 10.1124/jpet.112.202010. Epub 2013 Feb 13.

20.

Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: an in vitro investigation of genetic and splice variants.

Benoit-Biancamano MO, Connelly J, Villeneuve L, Caron P, Guillemette C.

Drug Metab Dispos. 2009 Feb;37(2):322-9. doi: 10.1124/dmd.108.023101. Epub 2008 Oct 29.

Supplemental Content

Support Center