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Items: 1 to 20 of 128

1.

A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2.

Parisien JP, Bamming D, Komuro A, Ramachandran A, Rodriguez JJ, Barber G, Wojahn RD, Horvath CM.

J Virol. 2009 Jul;83(14):7252-60. doi: 10.1128/JVI.00153-09. Epub 2009 Apr 29.

2.
3.

Amino acid requirements for MDA5 and LGP2 recognition by paramyxovirus V proteins: a single arginine distinguishes MDA5 from RIG-I.

Rodriguez KR, Horvath CM.

J Virol. 2013 Mar;87(5):2974-8. doi: 10.1128/JVI.02843-12. Epub 2012 Dec 26.

4.

Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2.

Bamming D, Horvath CM.

J Biol Chem. 2009 Apr 10;284(15):9700-12. doi: 10.1074/jbc.M807365200. Epub 2009 Feb 11.

5.

RIG-I-like receptors evolved adaptively in mammals, with parallel evolution at LGP2 and RIG-I.

Cagliani R, Forni D, Tresoldi C, Pozzoli U, Filippi G, Rainone V, De Gioia L, Clerici M, Sironi M.

J Mol Biol. 2014 Mar 20;426(6):1351-65. doi: 10.1016/j.jmb.2013.10.040. Epub 2013 Nov 7.

PMID:
24211720
6.

Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response.

Murali A, Li X, Ranjith-Kumar CT, Bhardwaj K, Holzenburg A, Li P, Kao CC.

J Biol Chem. 2008 Jun 6;283(23):15825-33. doi: 10.1074/jbc.M800542200. Epub 2008 Apr 14.

7.

Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.

Motz C, Schuhmann KM, Kirchhofer A, Moldt M, Witte G, Conzelmann KK, Hopfner KP.

Science. 2013 Feb 8;339(6120):690-3. doi: 10.1126/science.1230949. Epub 2013 Jan 17.

8.

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.

Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8.

9.

The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly.

Bruns AM, Leser GP, Lamb RA, Horvath CM.

Mol Cell. 2014 Sep 4;55(5):771-81. doi: 10.1016/j.molcel.2014.07.003. Epub 2014 Aug 7.

10.

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.

Saito T, Hirai R, Loo YM, Owen D, Johnson CL, Sinha SC, Akira S, Fujita T, Gale M Jr.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):582-7. Epub 2006 Dec 26.

11.

Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction.

Childs K, Randall R, Goodbourn S.

J Virol. 2012 Apr;86(7):3411-21. doi: 10.1128/JVI.06405-11. Epub 2012 Feb 1.

12.

The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.

Pippig DA, Hellmuth JC, Cui S, Kirchhofer A, Lammens K, Lammens A, Schmidt A, Rothenfusser S, Hopfner KP.

Nucleic Acids Res. 2009 Apr;37(6):2014-25. doi: 10.1093/nar/gkp059. Epub 2009 Feb 10.

13.
14.

The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA.

Li X, Ranjith-Kumar CT, Brooks MT, Dharmaiah S, Herr AB, Kao C, Li P.

J Biol Chem. 2009 May 15;284(20):13881-91. doi: 10.1074/jbc.M900818200. Epub 2009 Mar 11.

15.

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.

Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo YM, Gale M Jr, Akira S, Yonehara S, Kato A, Fujita T.

J Immunol. 2005 Sep 1;175(5):2851-8.

16.

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5.

Li X, Lu C, Stewart M, Xu H, Strong RK, Igumenova T, Li P.

Arch Biochem Biophys. 2009 Aug 1;488(1):23-33. doi: 10.1016/j.abb.2009.06.008. Epub 2009 Jun 14.

PMID:
19531363
17.

Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.

Takahasi K, Kumeta H, Tsuduki N, Narita R, Shigemoto T, Hirai R, Yoneyama M, Horiuchi M, Ogura K, Fujita T, Inagaki F.

J Biol Chem. 2009 Jun 26;284(26):17465-74. doi: 10.1074/jbc.M109.007179. Epub 2009 Apr 20.

18.

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells.

Deddouche S, Goubau D, Rehwinkel J, Chakravarty P, Begum S, Maillard PV, Borg A, Matthews N, Feng Q, van Kuppeveld FJ, Reis e Sousa C.

Elife. 2014 Feb 18;3:e01535. doi: 10.7554/eLife.01535.

19.

LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling.

Bruns AM, Horvath CM.

Cytokine. 2015 Aug;74(2):198-206. doi: 10.1016/j.cyto.2015.02.010. Epub 2015 Mar 18. Review.

20.

The immune evasion function of J and Beilong virus V proteins is distinct from that of other paramyxoviruses, consistent with their inclusion in the proposed genus Jeilongvirus.

Audsley MD, Marsh GA, Lieu KG, Tachedjian M, Joubert DA, Wang LF, Jans DA, Moseley GW.

J Gen Virol. 2016 Mar;97(3):581-92. doi: 10.1099/jgv.0.000388. Epub 2015 Dec 24.

PMID:
26703878

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