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Items: 1 to 20 of 173

1.

Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene.

Dawson MI, Ye M, Cao X, Farhana L, Hu QY, Zhao Y, Xu LP, Kiselyuk A, Correa RG, Yang L, Hou T, Reed JC, Itkin-Ansari P, Levine F, Sanner MF, Fontana JA, Zhang XK.

ChemMedChem. 2009 Jul;4(7):1106-19. doi: 10.1002/cmdc.200800447.

2.

Ligand Activity of Group 15 Compounds Possessing Triphenyl Substituent for the RXR and PPARγ Nuclear Receptors.

Hiromori Y, Ido A, Aoki A, Kimura T, Nagase H, Nakanishi T.

Biol Pharm Bull. 2016;39(10):1596-1603.

3.

Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma.

He BC, Chen L, Zuo GW, Zhang W, Bi Y, Huang J, Wang Y, Jiang W, Luo Q, Shi Q, Zhang BQ, Liu B, Lei X, Luo J, Luo X, Wagner ER, Kim SH, He CJ, Hu Y, Shen J, Zhou Q, Rastegar F, Deng ZL, Luu HH, He TC, Haydon RC.

Clin Cancer Res. 2010 Apr 15;16(8):2235-45. doi: 10.1158/1078-0432.CCR-09-2499. Epub 2010 Apr 6.

4.

Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode.

Zhang H, Li L, Chen L, Hu L, Jiang H, Shen X.

J Mol Biol. 2011 Mar 18;407(1):13-20. doi: 10.1016/j.jmb.2011.01.032. Epub 2011 Jan 22.

PMID:
21262235
5.

Determinants of retinoid X receptor transcriptional antagonism.

Cavasotto CN, Liu G, James SY, Hobbs PD, Peterson VJ, Bhattacharya AA, Kolluri SK, Zhang XK, Leid M, Abagyan R, Liddington RC, Dawson MI.

J Med Chem. 2004 Aug 26;47(18):4360-72.

PMID:
15317450
6.

Thiazolidinediones inhibit growth of gastrointestinal, biliary, and pancreatic adenocarcinoma cells through activation of the peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha pathway.

Tsujie M, Nakamori S, Okami J, Hayashi N, Hiraoka N, Nagano H, Dono K, Umeshita K, Sakon M, Monden M.

Exp Cell Res. 2003 Sep 10;289(1):143-51.

PMID:
12941612
7.

Selective allosteric ligand activation of the retinoid X receptor heterodimers of NGFI-B and Nurr1.

Morita K, Kawana K, Sodeyama M, Shimomura I, Kagechika H, Makishima M.

Biochem Pharmacol. 2005 Dec 19;71(1-2):98-107. Epub 2005 Nov 10.

PMID:
16288995
8.

Molecular determinants of magnolol targeting both RXRα and PPARγ.

Zhang H, Xu X, Chen L, Chen J, Hu L, Jiang H, Shen X.

PLoS One. 2011;6(11):e28253. doi: 10.1371/journal.pone.0028253. Epub 2011 Nov 29.

9.

Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression.

Burrage PS, Schmucker AC, Ren Y, Sporn MB, Brinckerhoff CE.

Arthritis Res Ther. 2008;10(6):R139. doi: 10.1186/ar2564. Epub 2008 Dec 1.

10.

An intact DNA-binding domain is not required for peroxisome proliferator-activated receptor gamma (PPARgamma) binding and activation on some PPAR response elements.

Temple KA, Cohen RN, Wondisford SR, Yu C, Deplewski D, Wondisford FE.

J Biol Chem. 2005 Feb 4;280(5):3529-40. Epub 2004 Nov 29.

11.

9-cis-retinoic acid up-regulates expression of transcriptional coregulator PELP1, a novel coactivator of the retinoid X receptor alpha pathway.

Singh RR, Gururaj AE, Vadlamudi RK, Kumar R.

J Biol Chem. 2006 Jun 2;281(22):15394-404. Epub 2006 Mar 30.

13.

Involvement of glucocorticoid receptor activation on anti-inflammatory effect induced by peroxisome proliferator-activated receptor γ agonist in mice.

Yamamoto A, Kakuta H, Sugimoto Y.

Int Immunopharmacol. 2014 Sep;22(1):204-8. doi: 10.1016/j.intimp.2014.06.028. Epub 2014 Jun 27.

PMID:
24975659
14.

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

Lee G, Elwood F, McNally J, Weiszmann J, Lindstrom M, Amaral K, Nakamura M, Miao S, Cao P, Learned RM, Chen JL, Li Y.

J Biol Chem. 2002 May 31;277(22):19649-57. Epub 2002 Mar 4.

15.

Transactivation of the human retinoid X receptor by organotins: use of site-directed mutagenesis to identify critical amino acid residues for organotin-induced transactivation.

Hiromori Y, Aoki A, Nishikawa J, Nagase H, Nakanishi T.

Metallomics. 2015 Jul;7(7):1180-8. doi: 10.1039/c5mt00086f.

PMID:
25985376
16.

The effect of antagonists on the conformational exchange of the retinoid X receptor alpha ligand-binding domain.

Lu J, Dawson MI, Hu QY, Xia Z, Dambacher JD, Ye M, Zhang XK, Li E.

Magn Reson Chem. 2009 Dec;47(12):1071-80. doi: 10.1002/mrc.2515.

17.

Identification of a naturally occurring retinoid X receptor agonist from Brazilian green propolis.

Nakashima K, Murakami T, Tanabe H, Inoue M.

Biochim Biophys Acta. 2014 Oct;1840(10):3034-41. doi: 10.1016/j.bbagen.2014.06.011. Epub 2014 Jun 24.

PMID:
24972164
18.

Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.

Ray DM, Spinelli SL, Pollock SJ, Murant TI, O'Brien JJ, Blumberg N, Francis CW, Taubman MB, Phipps RP.

Thromb Haemost. 2008 Jan;99(1):86-95. doi: 10.1160/TH07-05-0328.

20.

Growth inhibition of pancreatic cancer cells through activation of peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha pathway.

Tsujie M, Nakamori S, Okami J, Takahashi Y, Hayashi N, Nagano H, Dono K, Umeshita K, Sakon M, Monden M.

Int J Oncol. 2003 Aug;23(2):325-31.

PMID:
12851681

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