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Items: 1 to 20 of 80

1.

De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy.

Mashima T, Seimiya H, Tsuruo T.

Br J Cancer. 2009 May 5;100(9):1369-72. doi: 10.1038/sj.bjc.6605007. Epub 2009 Apr 7. Review.

2.

ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms.

Zaidi N, Royaux I, Swinnen JV, Smans K.

Mol Cancer Ther. 2012 Sep;11(9):1925-35. doi: 10.1158/1535-7163.MCT-12-0095. Epub 2012 Jun 20.

3.

The lipogenesis pathway as a cancer target.

Abramson HN.

J Med Chem. 2011 Aug 25;54(16):5615-38. doi: 10.1021/jm2005805. Epub 2011 Aug 3. No abstract available.

PMID:
21726077
4.

Glycerophospholipid synthesis as a novel drug target against cancer.

Dolce V, Cappello AR, Lappano R, Maggiolini M.

Curr Mol Pharmacol. 2011 Nov;4(3):167-75. Review.

PMID:
21222647
5.
6.

ATP citrate lyase inhibitors as novel cancer therapeutic agents.

Zu XY, Zhang QH, Liu JH, Cao RX, Zhong J, Yi GH, Quan ZH, Pizzorno G.

Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):154-67. Review.

PMID:
22339355
7.

Increased lipogenesis in cancer cells: new players, novel targets.

Swinnen JV, Brusselmans K, Verhoeven G.

Curr Opin Clin Nutr Metab Care. 2006 Jul;9(4):358-65. Review.

PMID:
16778563
8.

Fatty acid synthesis de novo in human adipose tissue.

Goldrick RB, Galton DJ.

Clin Sci Mol Med. 1974 Apr;46(4):469-79. No abstract available.

PMID:
4151447
9.
10.

Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells.

Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H.

Int J Cancer. 2014 Jul 1;135(1):37-47. doi: 10.1002/ijc.28652. Epub 2013 Dec 18.

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Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.

Moriya H, Uchida K, Okajima T, Matsuda T, Nadano D.

Arch Biochem Biophys. 2011 Apr 1;508(1):87-92. doi: 10.1016/j.abb.2011.01.015. Epub 2011 Jan 31.

PMID:
21281598
14.

Studies in vitro of lipogenesis in rat testicular tissue.

Whorton AR, Coniglio JG.

Lipids. 1975 Dec;10(12):783-9.

PMID:
1621
15.

Coupling of the de novo fatty acid biosynthesis and lipoylation pathways in mammalian mitochondria.

Witkowski A, Joshi AK, Smith S.

J Biol Chem. 2007 May 11;282(19):14178-85. Epub 2007 Mar 20.

16.

Androgens and the control of lipid metabolism in human prostate cancer cells.

Swinnen JV, Verhoeven G.

J Steroid Biochem Mol Biol. 1998 Apr;65(1-6):191-8. Review.

PMID:
9699873
18.

Fatty acid biosynthesis in liver and adipose tissue from dogs.

Baldner GL, Flatt RE, Shaw RN, Beitz DC.

Comp Biochem Physiol B. 1985;82(1):153-6.

PMID:
4053570
19.

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice.

Wang Q, Jiang L, Wang J, Li S, Yu Y, You J, Zeng R, Gao X, Rui L, Li W, Liu Y.

Hepatology. 2009 Apr;49(4):1166-75. doi: 10.1002/hep.22774.

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