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Items: 1 to 20 of 93

1.

Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis.

Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT.

Nature. 2009 May 7;459(7243):98-102. doi: 10.1038/nature07883. Epub 2009 Mar 22.

2.

Fused (Stk36) is a ciliary protein required for central pair assembly and motile cilia orientation in the mammalian oviduct.

Nozawa YI, Yao E, Lin C, Yang JH, Wilson CW, Gacayan R, Chuang PT.

Dev Dyn. 2013 Nov;242(11):1307-19. doi: 10.1002/dvdy.24024. Epub 2013 Sep 10.

3.

Contributions of Costal 2-Fused interactions to Hedgehog signaling in Drosophila.

Zadorozny EV, Little JC, Kalderon D.

Development. 2015 Mar 1;142(5):931-42. doi: 10.1242/dev.112904. Epub 2015 Jan 29.

4.

Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates.

Ben J, Elworthy S, Ng AS, van Eeden F, Ingham PW.

Development. 2011 Nov;138(22):4969-78. doi: 10.1242/dev.070862.

5.

Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction.

Evangelista M, Lim TY, Lee J, Parker L, Ashique A, Peterson AS, Ye W, Davis DP, de Sauvage FJ.

Sci Signal. 2008 Sep 30;1(39):ra7. doi: 10.1126/scisignal.1162925.

6.

Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.

Ruel L, Gallet A, Raisin S, Truchi A, Staccini-Lavenant L, Cervantes A, Thérond PP.

Development. 2007 Oct;134(20):3677-89. Epub 2007 Sep 19.

7.

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.

Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT.

Genes Dev. 2009 Aug 15;23(16):1910-28. doi: 10.1101/gad.1794109.

8.
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10.

Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling.

Raisin S, Ruel L, Ranieri N, Staccini-Lavenant L, Thérond PP.

Dev Biol. 2010 Aug 1;344(1):119-28. doi: 10.1016/j.ydbio.2010.04.021. Epub 2010 May 9.

11.

Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling pathway.

Monnier V, Dussillol F, Alves G, Lamour-Isnard C, Plessis A.

Curr Biol. 1998 May 7;8(10):583-6.

12.

Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused.

Nybakken KE, Turck CW, Robbins DJ, Bishop JM.

J Biol Chem. 2002 Jul 5;277(27):24638-47. Epub 2002 Apr 4.

13.

Genetic dissection of the Drosophila Cubitus interruptus signaling complex.

Lefers MA, Wang QT, Holmgren RA.

Dev Biol. 2001 Aug 15;236(2):411-20.

14.

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.

Endoh-Yamagami S, Evangelista M, Wilson D, Wen X, Theunissen JW, Phamluong K, Davis M, Scales SJ, Solloway MJ, de Sauvage FJ, Peterson AS.

Curr Biol. 2009 Aug 11;19(15):1320-6. doi: 10.1016/j.cub.2009.06.046. Epub 2009 Jul 9.

15.

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals.

Varjosalo M, Li SP, Taipale J.

Dev Cell. 2006 Feb;10(2):177-86.

16.

The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling.

Ascano M Jr, Nybakken KE, Sosinski J, Stegman MA, Robbins DJ.

Mol Cell Biol. 2002 Mar;22(5):1555-66.

17.

Cilia-mediated hedgehog signaling in Drosophila.

Kuzhandaivel A, Schultz SW, Alkhori L, Alenius M.

Cell Rep. 2014 May 8;7(3):672-80. doi: 10.1016/j.celrep.2014.03.052. Epub 2014 Apr 24.

18.

Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia.

Rink JC, Gurley KA, Elliott SA, Sánchez Alvarado A.

Science. 2009 Dec 4;326(5958):1406-10. doi: 10.1126/science.1178712. Epub 2009 Oct 22.

19.

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