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Items: 1 to 20 of 107

1.

Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments.

Salles FT, Merritt RC Jr, Manor U, Dougherty GW, Sousa AD, Moore JE, Yengo CM, Dosé AC, Kachar B.

Nat Cell Biol. 2009 Apr;11(4):443-50. doi: 10.1038/ncb1851.

2.

Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.

Merritt RC, Manor U, Salles FT, Grati M, Dose AC, Unrath WC, Quintero OA, Yengo CM, Kachar B.

Curr Biol. 2012 Feb 21;22(4):320-5. doi: 10.1016/j.cub.2011.12.053.

3.

Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.

Ebrahim S, Avenarius MR, Grati M, Krey JF, Windsor AM, Sousa AD, Ballesteros A, Cui R, Millis BA, Salles FT, Baird MA, Davidson MW, Jones SM, Choi D, Dong L, Raval MH, Yengo CM, Barr-Gillespie PG, Kachar B.

Nat Commun. 2016 Mar 1;7:10833. doi: 10.1038/ncomms10833.

4.

Competition and compensation: dissecting the biophysical and functional differences between the class 3 myosin paralogs, myosins 3a and 3b.

Manor U, Grati M, Yengo CM, Kachar B, Gov NS.

Bioarchitecture. 2012 Sep-Oct;2(5):171-4. doi: 10.4161/bioa.21733.

5.
6.

Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II.

Wang L, Zou J, Shen Z, Song E, Yang J.

Hum Mol Genet. 2012 Feb 1;21(3):692-710. doi: 10.1093/hmg/ddr503.

7.

Fascin 2b is a component of stereocilia that lengthens actin-based protrusions.

Chou SW, Hwang P, Gomez G, Fernando CA, West MC, Pollock LM, Lin-Jones J, Burnside B, McDermott BM Jr.

PLoS One. 2011;6(4):e14807. doi: 10.1371/journal.pone.0014807.

8.

A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression.

Schneider ME, Dosé AC, Salles FT, Chang W, Erickson FL, Burnside B, Kachar B.

J Neurosci. 2006 Oct 4;26(40):10243-52.

9.

Balanced levels of Espin are critical for stereociliary growth and length maintenance.

Rzadzinska A, Schneider M, Noben-Trauth K, Bartles JR, Kachar B.

Cell Motil Cytoskeleton. 2005 Nov;62(3):157-65.

PMID:
16206170
10.

Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice.

Sekerková G, Richter CP, Bartles JR.

PLoS Genet. 2011 Mar;7(3):e1002032. doi: 10.1371/journal.pgen.1002032.

11.

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia.

Peng AW, Belyantseva IA, Hsu PD, Friedman TB, Heller S.

J Neurosci. 2009 Dec 2;29(48):15083-8. doi: 10.1523/JNEUROSCI.2782-09.2009.

12.

Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.

Lelli A, Michel V, Boutet de Monvel J, Cortese M, Bosch-Grau M, Aghaie A, Perfettini I, Dupont T, Avan P, El-Amraoui A, Petit C.

J Cell Biol. 2016 Jan 18;212(2):231-44. doi: 10.1083/jcb.201509017.

13.
14.

Espins and the actin cytoskeleton of hair cell stereocilia and sensory cell microvilli.

Sekerková G, Zheng L, Loomis PA, Mugnaini E, Bartles JR.

Cell Mol Life Sci. 2006 Oct;63(19-20):2329-41. Review.

15.

Targeting of the hair cell proteins cadherin 23, harmonin, myosin XVa, espin, and prestin in an epithelial cell model.

Zheng L, Zheng J, Whitlon DS, García-Añoveros J, Bartles JR.

J Neurosci. 2010 May 26;30(21):7187-201. doi: 10.1523/JNEUROSCI.0852-10.2010.

16.

An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal.

Rzadzinska AK, Schneider ME, Davies C, Riordan GP, Kachar B.

J Cell Biol. 2004 Mar 15;164(6):887-97.

17.

Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop.

Quintero OA, Unrath WC, Stevens SM Jr, Manor U, Kachar B, Yengo CM.

J Biol Chem. 2013 Dec 27;288(52):37126-37. doi: 10.1074/jbc.M113.511014.

18.

Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle.

Belyantseva IA, Boger ET, Friedman TB.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13958-63.

19.

Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles.

Quintero OA, Moore JE, Unrath WC, Manor U, Salles FT, Grati M, Kachar B, Yengo CM.

J Biol Chem. 2010 Nov 12;285(46):35770-82. doi: 10.1074/jbc.M110.144360.

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