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Items: 1 to 20 of 107

1.

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Assmann A, Ueki K, Winnay JN, Kadowaki T, Kulkarni RN.

Mol Cell Biol. 2009 Jun;29(11):3219-28. doi: 10.1128/MCB.01489-08.

2.

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.

Venieratos PD, Drossopoulou GI, Kapodistria KD, Tsilibary EC, Kitsiou PV.

Cell Signal. 2010 May;22(5):791-800. doi: 10.1016/j.cellsig.2010.01.003.

PMID:
20067833
3.

Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.

Xuan S, Szabolcs M, Cinti F, Perincheri S, Accili D, Efstratiadis A.

J Biol Chem. 2010 Dec 24;285(52):41044-50. doi: 10.1074/jbc.M110.144790.

4.

Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation.

Tanabe K, Liu Y, Hasan SD, Martinez SC, Cras-Méneur C, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA.

PLoS One. 2011 Apr 26;6(4):e18146. doi: 10.1371/journal.pone.0018146.

5.

Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation.

Bartolomé A, Guillén C, Benito M.

Endocrinology. 2010 Jul;151(7):3084-94. doi: 10.1210/en.2010-0048.

PMID:
20427478
6.

Differential mitogenic signaling in insulin receptor-deficient fetal pancreatic beta-cells.

Guillen C, Navarro P, Robledo M, Valverde AM, Benito M.

Endocrinology. 2006 Apr;147(4):1959-68.

PMID:
16396989
7.

Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells.

Karnevi E, Said K, Andersson R, Rosendahl AH.

BMC Cancer. 2013 May 10;13:235. doi: 10.1186/1471-2407-13-235.

8.

Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells.

Cahuana GM, Tejedo JR, Hmadcha A, Ramírez R, Cuesta AL, Soria B, Martin F, Bedoya FJ.

Cell Signal. 2008 Feb;20(2):301-10.

PMID:
18023142
10.

Effect of zinc on regulation of insulin-like growth factor signaling in human androgen-independent prostate cancer cells.

Banudevi S, Senthilkumar K, Sharmila G, Arunkumar R, Vijayababu MR, Arunakaran J.

Clin Chim Acta. 2010 Feb;411(3-4):172-8. doi: 10.1016/j.cca.2009.10.023.

PMID:
19913001
11.

Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.

Martinez SC, Cras-Méneur C, Bernal-Mizrachi E, Permutt MA.

Diabetes. 2006 Jun;55(6):1581-91.

12.

Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue.

Beery R, Haimsohn M, Wertheim N, Hemi R, Nir U, Karasik A, Kanety H, Geier A.

Endocrinology. 2001 Jul;142(7):3098-107.

PMID:
11416032
13.

Palmitate affects insulin receptor phosphorylation and intracellular insulin signal in a pancreatic alpha-cell line.

Piro S, Maniscalchi ET, Monello A, Pandini G, Mascali LG, Rabuazzo AM, Purrello F.

Endocrinology. 2010 Sep;151(9):4197-206. doi: 10.1210/en.2009-1472.

PMID:
20573722
14.

Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.

D'Alessandris C, Andreozzi F, Federici M, Cardellini M, Brunetti A, Ranalli M, Del Guerra S, Lauro D, Del Prato S, Marchetti P, Lauro R, Sesti G.

FASEB J. 2004 Jun;18(9):959-61.

PMID:
15059979
15.

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

Wang H, Gambosova K, Cooper ZA, Holloway MP, Kassai A, Izquierdo D, Cleveland K, Boney CM, Altura RA.

BMC Mol Biol. 2010 Aug 31;11:66. doi: 10.1186/1471-2199-11-66.

18.

PDGF- and insulin/IGF-1-specific distinct modes of class IA PI 3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells.

Biswas SK, Zhao Y, Nagalingam A, Gardner TW, Sandirasegarane L.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3687-98. doi: 10.1167/iovs.07-1455.

PMID:
18421086
19.

Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action.

Fulzele K, DiGirolamo DJ, Liu Z, Xu J, Messina JL, Clemens TL.

J Biol Chem. 2007 Aug 31;282(35):25649-58.

20.

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