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Items: 1 to 20 of 100

1.

RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B.

Manukyan M, Nalbant P, Luxen S, Hahn KM, Knaus UG.

J Immunol. 2009 Mar 15;182(6):3522-9. doi: 10.4049/jimmunol.0802280.

2.

AKAP13, a RhoA GTPase-specific guanine exchange factor, is a novel regulator of TLR2 signaling.

Shibolet O, Giallourakis C, Rosenberg I, Mueller T, Xavier RJ, Podolsky DK.

J Biol Chem. 2007 Nov 30;282(48):35308-17. Epub 2007 Sep 18.

3.

The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway.

Cai M, Li M, Wang K, Wang S, Lu Q, Yan J, Mossman KL, Lin R, Zheng C.

PLoS One. 2013;8(1):e54586. doi: 10.1371/journal.pone.0054586. Epub 2013 Jan 28.

4.
5.

RhoA/ROCK-dependent pathway is required for TLR2-mediated IL-23 production in human synovial macrophages: suppression by cilostazol.

Park SY, Lee SW, Lee WS, Rhim BY, Lee SJ, Kwon SM, Hong KW, Kim CD.

Biochem Pharmacol. 2013 Nov 1;86(9):1320-7. doi: 10.1016/j.bcp.2013.08.017. Epub 2013 Aug 22.

6.
7.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

8.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

9.

Heterotrimeric Gi/Go proteins modulate endothelial TLR signaling independent of the MyD88-dependent pathway.

Dauphinee SM, Voelcker V, Tebaykina Z, Wong F, Karsan A.

Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2246-53. doi: 10.1152/ajpheart.01194.2010. Epub 2011 Sep 23.

10.

Src-family-tyrosine kinase Lyn is critical for TLR2-mediated NF-κB activation through the PI 3-kinase signaling pathway.

Toubiana J, Rossi AL, Belaidouni N, Grimaldi D, Pene F, Chafey P, Comba B, Camoin L, Bismuth G, Claessens YE, Mira JP, Chiche JD.

Innate Immun. 2015 Oct;21(7):685-97. doi: 10.1177/1753425915586075. Epub 2015 Jun 8.

PMID:
26055819
11.

TLR3 ligand induces NF-{kappa}B activation and various fates of multiple myeloma cells depending on IFN-{alpha} production.

Chiron D, Pellat-Deceunynck C, Amiot M, Bataille R, Jego G.

J Immunol. 2009 Apr 1;182(7):4471-8. doi: 10.4049/jimmunol.0803113.

12.

Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response.

Boyd JH, Mathur S, Wang Y, Bateman RM, Walley KR.

Cardiovasc Res. 2006 Dec 1;72(3):384-93. Epub 2006 Sep 23.

PMID:
17054926
13.

CD300F blocks both MyD88 and TRIF-mediated TLR signaling through activation of Src homology region 2 domain-containing phosphatase 1.

Lee SM, Kim EJ, Suk K, Lee WH.

J Immunol. 2011 Jun 1;186(11):6296-303. doi: 10.4049/jimmunol.1002184. Epub 2011 May 2.

14.

Activation of Toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors.

Goto Y, Arigami T, Kitago M, Nguyen SL, Narita N, Ferrone S, Morton DL, Irie RF, Hoon DS.

Mol Cancer Ther. 2008 Nov;7(11):3642-53. doi: 10.1158/1535-7163.MCT-08-0582.

15.

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.

Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, Akira S.

J Immunol. 2002 Dec 15;169(12):6668-72.

16.

GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-κB.

Guo F, Zhou Z, Dou Y, Tang J, Gao C, Huan J.

Cytokine. 2012 Mar;57(3):417-28. doi: 10.1016/j.cyto.2011.12.009. Epub 2012 Jan 9.

PMID:
22226621
18.

IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29.

Sirén J, Pirhonen J, Julkunen I, Matikainen S.

J Immunol. 2005 Feb 15;174(4):1932-7.

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20.

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway.

Arbibe L, Mira JP, Teusch N, Kline L, Guha M, Mackman N, Godowski PJ, Ulevitch RJ, Knaus UG.

Nat Immunol. 2000 Dec;1(6):533-40.

PMID:
11101877

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