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Items: 1 to 20 of 230

1.

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X.

J Biol Chem. 2009 May 1;284(18):12297-305. doi: 10.1074/jbc.M900573200. Epub 2009 Mar 3.

2.

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.

Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH.

Mol Biol Cell. 2009 Apr;20(7):1992-2003. doi: 10.1091/mbc.E08-12-1249. Epub 2009 Feb 18.

3.

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N.

Mol Biol Cell. 2009 Apr;20(7):1981-91. doi: 10.1091/mbc.E08-12-1248. Epub 2009 Feb 11.

4.

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

Mercer CA, Kaliappan A, Dennis PB.

Autophagy. 2009 Jul;5(5):649-62. Epub 2009 Jul 20.

PMID:
19287211
5.

mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex.

Chan EY.

Sci Signal. 2009 Aug 18;2(84):pe51. doi: 10.1126/scisignal.284pe51.

PMID:
19690328
6.

Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.

Alers S, Löffler AS, Paasch F, Dieterle AM, Keppeler H, Lauber K, Campbell DG, Fehrenbacher B, Schaller M, Wesselborg S, Stork B.

Autophagy. 2011 Dec;7(12):1423-33.

PMID:
22024743
7.

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.

Gammoh N, Florey O, Overholtzer M, Jiang X.

Nat Struct Mol Biol. 2013 Feb;20(2):144-9. doi: 10.1038/nsmb.2475. Epub 2012 Dec 23.

8.

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.

Park JM, Jung CH, Seo M, Otto NM, Grunwald D, Kim KH, Moriarity B, Kim YM, Starker C, Nho RS, Voytas D, Kim DH.

Autophagy. 2016;12(3):547-64. doi: 10.1080/15548627.2016.1140293.

9.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

10.

Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy.

Joo JH, Dorsey FC, Joshi A, Hennessy-Walters KM, Rose KL, McCastlain K, Zhang J, Iyengar R, Jung CH, Suen DF, Steeves MA, Yang CY, Prater SM, Kim DH, Thompson CB, Youle RJ, Ney PA, Cleveland JL, Kundu M.

Mol Cell. 2011 Aug 19;43(4):572-85. doi: 10.1016/j.molcel.2011.06.018.

11.

Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy.

Puente C, Hendrickson RC, Jiang X.

J Biol Chem. 2016 Mar 11;291(11):6026-35. doi: 10.1074/jbc.M115.689646. Epub 2016 Jan 22.

12.

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.

Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N.

J Cell Biol. 2008 May 5;181(3):497-510. doi: 10.1083/jcb.200712064. Epub 2008 Apr 28.

13.

The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG.

PLoS One. 2010 Nov 3;5(11):e15394. doi: 10.1371/journal.pone.0015394.

14.

Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death.

Gao W, Shen Z, Shang L, Wang X.

Cell Death Differ. 2011 Oct;18(10):1598-607. doi: 10.1038/cdd.2011.33. Epub 2011 Apr 8.

15.

Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.

Liu CC, Lin YC, Chen YH, Chen CM, Pang LY, Chen HA, Wu PR, Lin MY, Jiang ST, Tsai TF, Chen RH.

Mol Cell. 2016 Jan 7;61(1):84-97. doi: 10.1016/j.molcel.2015.11.001. Epub 2015 Dec 10.

16.

ATG13: just a companion, or an executor of the autophagic program?

Alers S, Wesselborg S, Stork B.

Autophagy. 2014 Jun;10(6):944-56. doi: 10.4161/auto.28987. Review. Erratum in: Autophagy. 2014 Aug;10(8):1481.

17.

Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex.

Qi S, Kim DJ, Stjepanovic G, Hurley JH.

Structure. 2015 Oct 6;23(10):1848-57. doi: 10.1016/j.str.2015.07.011. Epub 2015 Aug 20.

18.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

19.

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.

Chan EY, Longatti A, McKnight NC, Tooze SA.

Mol Cell Biol. 2009 Jan;29(1):157-71. doi: 10.1128/MCB.01082-08. Epub 2008 Oct 20.

20.

Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17?

Hara T, Mizushima N.

Autophagy. 2009 Jan;5(1):85-7. Epub 2009 Jan 13.

PMID:
18981720

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