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Items: 1 to 20 of 148

1.

Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (Danio rerio) lateral line and mouse (Mus musculus) utricle.

Ou HC, Cunningham LL, Francis SP, Brandon CS, Simon JA, Raible DW, Rubel EW.

J Assoc Res Otolaryngol. 2009 Jun;10(2):191-203. doi: 10.1007/s10162-009-0158-y. Epub 2009 Feb 25.

2.

Using the zebrafish lateral line to screen for ototoxicity.

Chiu LL, Cunningham LL, Raible DW, Rubel EW, Ou HC.

J Assoc Res Otolaryngol. 2008 Jun;9(2):178-90. doi: 10.1007/s10162-008-0118-y. Epub 2008 Apr 12.

3.

Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.

Vlasits AL, Simon JA, Raible DW, Rubel EW, Owens KN.

Hear Res. 2012 Dec;294(1-2):153-65. doi: 10.1016/j.heares.2012.08.002. Epub 2012 Aug 31.

4.

Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line.

Ou HC, Keating S, Wu P, Simon JA, Raible DW, Rubel EW.

J Assoc Res Otolaryngol. 2012 Dec;13(6):759-70. doi: 10.1007/s10162-012-0353-0. Epub 2012 Oct 10.

5.

Identification of small molecule inhibitors of cisplatin-induced hair cell death: results of a 10,000 compound screen in the zebrafish lateral line.

Thomas AJ, Wu P, Raible DW, Rubel EW, Simon JA, Ou HC.

Otol Neurotol. 2015 Mar;36(3):519-25. doi: 10.1097/MAO.0000000000000487.

6.

Developmental differences in susceptibility to neomycin-induced hair cell death in the lateral line neuromasts of zebrafish (Danio rerio).

Murakami SL, Cunningham LL, Werner LA, Bauer E, Pujol R, Raible DW, Rubel EW.

Hear Res. 2003 Dec;186(1-2):47-56.

PMID:
14644458
7.

Lateral line hair cell maturation is a determinant of aminoglycoside susceptibility in zebrafish (Danio rerio).

Santos F, MacDonald G, Rubel EW, Raible DW.

Hear Res. 2006 Mar;213(1-2):25-33. Epub 2006 Feb 3.

PMID:
16459035
9.

Ototoxin-induced cellular damage in neuromasts disrupts lateral line function in larval zebrafish.

Buck LM, Winter MJ, Redfern WS, Whitfield TT.

Hear Res. 2012 Feb;284(1-2):67-81. doi: 10.1016/j.heares.2011.12.001. Epub 2011 Dec 11.

PMID:
22183155
10.

Ultrastructural analysis of aminoglycoside-induced hair cell death in the zebrafish lateral line reveals an early mitochondrial response.

Owens KN, Cunningham DE, MacDonald G, Rubel EW, Raible DW, Pujol R.

J Comp Neurol. 2007 Jun 1;502(4):522-43.

PMID:
17394157
11.

Aminoglycoside-induced hair cell death of inner ear organs causes functional deficits in adult zebrafish (Danio rerio).

Uribe PM, Sun H, Wang K, Asuncion JD, Wang Q, Chen CW, Steyger PS, Smith ME, Matsui JI.

PLoS One. 2013;8(3):e58755. doi: 10.1371/journal.pone.0058755. Epub 2013 Mar 22.

12.

Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death.

Owens KN, Santos F, Roberts B, Linbo T, Coffin AB, Knisely AJ, Simon JA, Rubel EW, Raible DW.

PLoS Genet. 2008 Feb 29;4(2):e1000020. doi: 10.1371/journal.pgen.1000020.

13.

Hair cell toxicity in anti-cancer drugs: evaluating an anti-cancer drug library for independent and synergistic toxic effects on hair cells using the zebrafish lateral line.

Hirose Y, Simon JA, Ou HC.

J Assoc Res Otolaryngol. 2011 Dec;12(6):719-28. doi: 10.1007/s10162-011-0278-z. Epub 2011 Jul 6.

14.

Drug screening for hearing loss: using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss.

Ou HC, Santos F, Raible DW, Simon JA, Rubel EW.

Drug Discov Today. 2010 Apr;15(7-8):265-71. doi: 10.1016/j.drudis.2010.01.001. Epub 2010 Jan 22. Review.

15.

Chemical screening for hair cell loss and protection in the zebrafish lateral line.

Coffin AB, Ou H, Owens KN, Santos F, Simon JA, Rubel EW, Raible DW.

Zebrafish. 2010 Mar;7(1):3-11. doi: 10.1089/zeb.2009.0639. Review.

16.

Fucoidan promotes mechanosensory hair cell regeneration following amino glycoside-induced cell death.

Moon IS, So JH, Jung YM, Lee WS, Kim EY, Choi JH, Kim CH, Choi JY.

Hear Res. 2011 Dec;282(1-2):236-42. doi: 10.1016/j.heares.2011.07.007. Epub 2011 Jul 23.

PMID:
21810458
17.

Protective role of L-ascorbic acid, N-acetylcysteine and apocynin on neomycin-induced hair cell loss in zebrafish.

Wu CY, Lee HJ, Liu CF, Korivi M, Chen HH, Chan MH.

J Appl Toxicol. 2015 Mar;35(3):273-9. doi: 10.1002/jat.3043. Epub 2014 Aug 4.

PMID:
25092119
18.

Cisplatin-induced hair cell loss in zebrafish (Danio rerio) lateral line.

Ou HC, Raible DW, Rubel EW.

Hear Res. 2007 Nov;233(1-2):46-53. Epub 2007 Jul 19.

19.

Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line.

Coffin AB, Reinhart KE, Owens KN, Raible DW, Rubel EW.

Hear Res. 2009 Jul;253(1-2):42-51. doi: 10.1016/j.heares.2009.03.004. Epub 2009 Mar 12.

20.

Hsp70 inhibits aminoglycoside-induced hair cell death and is necessary for the protective effect of heat shock.

Taleb M, Brandon CS, Lee FS, Lomax MI, Dillmann WH, Cunningham LL.

J Assoc Res Otolaryngol. 2008 Sep;9(3):277-89. doi: 10.1007/s10162-008-0122-2. Epub 2008 May 30.

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