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Items: 1 to 20 of 76

1.

Grape seed polyphenolic extract as a potential novel therapeutic agent in tauopathies.

Ho L, Yemul S, Wang J, Pasinetti GM.

J Alzheimers Dis. 2009;16(2):433-9. doi: 10.3233/JAD-2009-0969.

2.

Development of a grape seed polyphenolic extract with anti-oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies.

Pasinetti GM, Ksiezak-Reding H, Santa-Maria I, Wang J, Ho L.

J Neurochem. 2010 Sep;114(6):1557-68. doi: 10.1111/j.1471-4159.2010.06875.x. Epub 2010 Jul 27. Review.

3.

GSPE interferes with tau aggregation in vivo: implication for treating tauopathy.

Santa-Maria I, Diaz-Ruiz C, Ksiezak-Reding H, Chen A, Ho L, Wang J, Pasinetti GM.

Neurobiol Aging. 2012 Sep;33(9):2072-81. doi: 10.1016/j.neurobiolaging.2011.09.027. Epub 2011 Nov 4.

4.

Polyphenolic compounds for treating neurodegenerative disorders involving protein misfolding.

Ho L, Pasinetti GM.

Expert Rev Proteomics. 2010 Aug;7(4):579-89. doi: 10.1586/epr.10.69. Review.

PMID:
20653511
5.

Ultrastructural alterations of Alzheimer's disease paired helical filaments by grape seed-derived polyphenols.

Ksiezak-Reding H, Ho L, Santa-Maria I, Diaz-Ruiz C, Wang J, Pasinetti GM.

Neurobiol Aging. 2012 Jul;33(7):1427-39. doi: 10.1016/j.neurobiolaging.2010.11.006. Epub 2010 Dec 31.

PMID:
21196065
6.

Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease.

Wang J, Santa-Maria I, Ho L, Ksiezak-Reding H, Ono K, Teplow DB, Pasinetti GM.

J Alzheimers Dis. 2010;22(2):653-61. doi: 10.3233/JAD-2010-101074.

PMID:
20858961
7.

Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy.

Pfleger CM, Wang J, Friedman L, Vittorino R, Conley LM, Ho L, Fivecoat HC, Pasinetti GM.

Int J Alzheimers Dis. 2010 Aug 24;2010. pii: 576357. doi: 10.4061/2010/576357.

8.

Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention.

Bagchi D, Bagchi M, Stohs SJ, Das DK, Ray SD, Kuszynski CA, Joshi SS, Pruess HG.

Toxicology. 2000 Aug 7;148(2-3):187-97.

PMID:
10962138
9.

Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau.

Li W, Sperry JB, Crowe A, Trojanowski JQ, Smith AB 3rd, Lee VM.

J Neurochem. 2009 Aug;110(4):1339-51. doi: 10.1111/j.1471-4159.2009.06224.x. Epub 2009 Jun 15. Erratum in: J Neurochem. 2009 Sep;110(6):1989.

10.

Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease.

Ferruzzi MG, Lobo JK, Janle EM, Cooper B, Simon JE, Wu QL, Welch C, Ho L, Weaver C, Pasinetti GM.

J Alzheimers Dis. 2009;18(1):113-24. doi: 10.3233/JAD-2009-1135.

11.

Neuron-selective toxicity of tau peptide in a cell culture model of neurodegenerative tauopathy: essential role for aggregation in neurotoxicity.

Zhao K, Ippolito G, Wang L, Price V, Kim MH, Cornwell G, Fulenchek S, Breen GA, Goux WJ, D'Mello SR.

J Neurosci Res. 2010 Nov 15;88(15):3399-413. doi: 10.1002/jnr.22485.

PMID:
20882568
12.

POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON'S DISEASE.

Wang J, Pfleger CM, Friedman L, Vittorino R, Zhao W, Qian X, Conley L, Ho L, Pasinetti GM.

Transl Neurosci. 2010 Jun 1;1(2):95-100.

13.

Novel drugs affecting tau behavior in the treatment of Alzheimer's disease and tauopathies.

Navarrete LP, Pérez P, Morales I, Maccioni RB.

Curr Alzheimer Res. 2011 Sep;8(6):678-85. Review.

PMID:
21605038
14.

Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization.

Wang D, Ho L, Faith J, Ono K, Janle EM, Lachcik PJ, Cooper BR, Jannasch AH, D'Arcy BR, Williams BA, Ferruzzi MG, Levine S, Zhao W, Dubner L, Pasinetti GM.

Mol Nutr Food Res. 2015 Jun;59(6):1025-40. doi: 10.1002/mnfr.201400544. Epub 2015 Apr 27. Erratum in: Mol Nutr Food Res. 2015 Jun;59(6):1222. Mol Nutr Food Res. 2015 Nov;59(11):2337.

15.

Further understanding of tau phosphorylation: implications for therapy.

Medina M, Avila J.

Expert Rev Neurother. 2015 Jan;15(1):115-22. doi: 10.1586/14737175.2015.1000864. Epub 2015 Jan 2. Review.

PMID:
25555397
16.

Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins.

Taniguchi S, Suzuki N, Masuda M, Hisanaga S, Iwatsubo T, Goedert M, Hasegawa M.

J Biol Chem. 2005 Mar 4;280(9):7614-23. Epub 2004 Dec 17.

17.

Mechanisms of tau self-aggregation and neurotoxicity.

Farías G, Cornejo A, Jiménez J, Guzmán L, Maccioni RB.

Curr Alzheimer Res. 2011 Sep;8(6):608-14. Review.

PMID:
21605046
18.

Targeting heat shock proteins in tauopathies.

Deture M, Hicks C, Petrucelli L.

Curr Alzheimer Res. 2010 Dec;7(8):677-84. Review.

PMID:
20678072
19.

Acute and long-term safety evaluation of a novel IH636 grape seed proanthocyanidin extract.

Ray S, Bagchi D, Lim PM, Bagchi M, Gross SM, Kothari SC, Preuss HG, Stohs SJ.

Res Commun Mol Pathol Pharmacol. 2001 Mar-Apr;109(3-4):165-97.

PMID:
11758648
20.

Misfolded tau protein and disease modifying pathways in transgenic rodent models of human tauopathies.

Zilka N, Korenova M, Novak M.

Acta Neuropathol. 2009 Jul;118(1):71-86. doi: 10.1007/s00401-009-0499-y. Epub 2009 Feb 24. Review.

PMID:
19238406

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