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The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.

Shen ZJ, Esnault S, Schinzel A, Borner C, Malter JS.

Nat Immunol. 2009 Mar;10(3):257-65. doi: 10.1038/ni.1697. Epub 2009 Feb 1.


Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils.

Oh J, Malter JS.

J Immunol. 2013 May 15;190(10):4937-45. doi: 10.4049/jimmunol.1202646. Epub 2013 Apr 19.


Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity.

Barone MC, Desouza LA, Freeman RS.

J Neurochem. 2008 Jul;106(2):734-45. doi: 10.1111/j.1471-4159.2008.05427.x. Epub 2008 Apr 14.


Oxidant-mediated mitochondrial injury in eosinophil apoptosis: enhancement by glucocorticoids and inhibition by granulocyte-macrophage colony-stimulating factor.

Gardai SJ, Hoontrakoon R, Goddard CD, Day BJ, Chang LY, Henson PM, Bratton DL.

J Immunol. 2003 Jan 1;170(1):556-66.


A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx.

Ryo A, Hirai A, Nishi M, Liou YC, Perrem K, Lin SC, Hirano H, Lee SW, Aoki I.

J Biol Chem. 2007 Dec 14;282(50):36671-81. Epub 2007 Oct 15.


The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation.

Lee NY, Choi HK, Shim JH, Kang KW, Dong Z, Choi HS.

Carcinogenesis. 2009 Apr;30(4):671-81. doi: 10.1093/carcin/bgp027. Epub 2009 Jan 23.


The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1.

Khanal P, Namgoong GM, Kang BS, Woo ER, Choi HS.

Mol Cancer Ther. 2010 Mar;9(3):606-16. doi: 10.1158/1535-7163.MCT-09-0560. Epub 2010 Feb 23.


Inhibition of peptidyl-prolyl cis/trans isomerase Pin1 induces cell cycle arrest and apoptosis in vascular smooth muscle cells.

Lv L, Zhou Z, Huang X, Zhao Y, Zhang L, Shi Y, Sun M, Zhang J.

Apoptosis. 2010 Jan;15(1):41-54. doi: 10.1007/s10495-009-0409-8.


Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.

Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS.

J Clin Invest. 2008 Feb;118(2):479-90. doi: 10.1172/JCI32789.


Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis.

Follis AV, Llambi F, Merritt P, Chipuk JE, Green DR, Kriwacki RW.

Mol Cell. 2015 Aug 20;59(4):677-84. doi: 10.1016/j.molcel.2015.06.029. Epub 2015 Jul 30.


Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins.

Rudrabhatla P, Albers W, Pant HC.

J Neurosci. 2009 Nov 25;29(47):14869-80. doi: 10.1523/JNEUROSCI.4469-09.2009.


Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1.

Pathan N, Aime-Sempe C, Kitada S, Haldar S, Reed JC.

Neoplasia. 2001 Jan-Feb;3(1):70-9.


Role for Bcl-xL in delayed eosinophil apoptosis mediated by granulocyte-macrophage colony-stimulating factor and interleukin-5.

Dibbert B, Daigle I, Braun D, Schranz C, Weber M, Blaser K, Zangemeister-Wittke U, Akbar AN, Simon HU.

Blood. 1998 Aug 1;92(3):778-83.


Microtubule-targeting drugs induce bcl-2 phosphorylation and association with Pin1.

Pathan N, Aime-Sempe C, Kitada S, Basu A, Haldar S, Reed JC.

Neoplasia. 2001 Nov-Dec;3(6):550-9.


Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

Monje P, Hernández-Losa J, Lyons RJ, Castellone MD, Gutkind JS.

J Biol Chem. 2005 Oct 21;280(42):35081-4. Epub 2005 Aug 25.


The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins.

Shen M, Stukenberg PT, Kirschner MW, Lu KP.

Genes Dev. 1998 Mar 1;12(5):706-20.


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