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Anthrax protective antigen delivered by Salmonella enterica serovar Typhi Ty21a protects mice from a lethal anthrax spore challenge.

Osorio M, Wu Y, Singh S, Merkel TJ, Bhattacharyya S, Blake MS, Kopecko DJ.

Infect Immun. 2009 Apr;77(4):1475-82. doi: 10.1128/IAI.00828-08. Epub 2009 Jan 29.


Towards a human oral vaccine for anthrax: the utility of a Salmonella Typhi Ty21a-based prime-boost immunization strategy.

Baillie LW, Rodriguez AL, Moore S, Atkins HS, Feng C, Nataro JP, Pasetti MF.

Vaccine. 2008 Nov 11;26(48):6083-91. doi: 10.1016/j.vaccine.2008.09.010. Epub 2008 Sep 19.


Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis.

Stokes MG, Titball RW, Neeson BN, Galen JE, Walker NJ, Stagg AJ, Jenner DC, Thwaite JE, Nataro JP, Baillie LW, Atkins HS.

Infect Immun. 2007 Apr;75(4):1827-34. Epub 2006 Dec 4.


A plant based protective antigen [PA(dIV)] vaccine expressed in chloroplasts demonstrates protective immunity in mice against anthrax.

Gorantala J, Grover S, Goel D, Rahi A, Jayadev Magani SK, Chandra S, Bhatnagar R.

Vaccine. 2011 Jun 15;29(27):4521-33. doi: 10.1016/j.vaccine.2011.03.082. Epub 2011 Apr 17.


Immunogenicity and efficacy of an anthrax/plague DNA fusion vaccine in a mouse model.

Albrecht MT, Eyles JE, Baillie LW, Keane-Myers AM.

FEMS Immunol Med Microbiol. 2012 Aug;65(3):505-9. doi: 10.1111/j.1574-695X.2012.00974.x. Epub 2012 May 21.


Efficacy and immunogenicity of single-dose AdVAV intranasal anthrax vaccine compared to anthrax vaccine absorbed in an aerosolized spore rabbit challenge model.

Krishnan V, Andersen BH, Shoemaker C, Sivko GS, Tordoff KP, Stark GV, Zhang J, Feng T, Duchars M, Roberts MS.

Clin Vaccine Immunol. 2015 Apr;22(4):430-9. doi: 10.1128/CVI.00690-14. Epub 2015 Feb 11.


A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores.

Hermanson G, Whitlow V, Parker S, Tonsky K, Rusalov D, Ferrari M, Lalor P, Komai M, Mere R, Bell M, Brenneman K, Mateczun A, Evans T, Kaslow D, Galloway D, Hobart P.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13601-6. Epub 2004 Sep 1.


Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax.

Skoble J, Beaber JW, Gao Y, Lovchik JA, Sower LE, Liu W, Luckett W, Peterson JW, Calendar R, Portnoy DA, Lyons CR, Dubensky TW Jr.

Infect Immun. 2009 Apr;77(4):1649-63. doi: 10.1128/IAI.00530-08. Epub 2009 Jan 21.


The role of antibodies to Bacillus anthracis and anthrax toxin components in inhibiting the early stages of infection by anthrax spores.

Welkos S, Little S, Friedlander A, Fritz D, Fellows P.

Microbiology. 2001 Jun;147(Pt 6):1677-85.


Mucosal immunization with a novel nanoemulsion-based recombinant anthrax protective antigen vaccine protects against Bacillus anthracis spore challenge.

Bielinska AU, Janczak KW, Landers JJ, Makidon P, Sower LE, Peterson JW, Baker JR Jr.

Infect Immun. 2007 Aug;75(8):4020-9. Epub 2007 May 14.


Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection.

Reed MD, Wilder JA, Mega WM, Hutt JA, Kuehl PJ, Valderas MW, Chew LL, Liang BC, Squires CH.

PLoS One. 2015 Jul 24;10(7):e0130952. doi: 10.1371/journal.pone.0130952. eCollection 2015.


Enhancement of antibody responses to Bacillus anthracis protective antigen domain IV by use of calreticulin as a chimeric molecular adjuvant.

Park YS, Lee JH, Hung CF, Wu TC, Kim TW.

Infect Immun. 2008 May;76(5):1952-9. doi: 10.1128/IAI.01722-07. Epub 2008 Feb 19.


Recombinant vaccine displaying the loop-neutralizing determinant from protective antigen completely protects rabbits from experimental inhalation anthrax.

Oscherwitz J, Yu F, Jacobs JL, Cease KB.

Clin Vaccine Immunol. 2013 Mar;20(3):341-9. doi: 10.1128/CVI.00612-12. Epub 2013 Jan 2.


An intranasal vaccine targeting both the Bacillus anthracis toxin and bacterium provides protection against aerosol spore challenge in rabbits.

Wimer-Mackin S, Hinchcliffe M, Petrie CR, Warwood SJ, Tino WT, Williams MS, Stenz JP, Cheff A, Richardson C.

Vaccine. 2006 May 1;24(18):3953-63. Epub 2006 Feb 28.


Protection of mice against challenge with Bacillus anthracis STI spores after DNA vaccination.

Hahn UK, Alex M, Czerny CP, Böhm R, Beyer W.

Int J Med Microbiol. 2004 Jul;294(1):35-44.


Efficacy of a vaccine based on protective antigen and killed spores against experimental inhalational anthrax.

Gauthier YP, Tournier JN, Paucod JC, Corre JP, Mock M, Goossens PL, Vidal DR.

Infect Immun. 2009 Mar;77(3):1197-207. doi: 10.1128/IAI.01217-08. Epub 2008 Dec 29.


Targeted expression of anthrax protective antigen by Lactobacillus gasseri as an anthrax vaccine.

Mohamadzadeh M, Durmaz E, Zadeh M, Pakanati KC, Gramarossa M, Cohran V, Klaenhammer TR.

Future Microbiol. 2010 Aug;5(8):1289-96. doi: 10.2217/fmb.10.78.


Detoxified lethal toxin as a potential mucosal vaccine against anthrax.

Xu Q, Zeng M.

Clin Vaccine Immunol. 2008 Apr;15(4):612-6. doi: 10.1128/CVI.00402-07. Epub 2008 Feb 6.

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