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Items: 1 to 20 of 110

1.

From genome-based in silico predictions to ex vivo verification of leprosy diagnosis.

Geluk A, Spencer JS, Bobosha K, Pessolani MC, Pereira GM, Banu S, Honoré N, Reece ST, MacDonald M, Sapkota BR, Ranjit C, Franken KL, Zewdie M, Aseffa A, Hussain R, Stefani MM, Cho SN, Oskam L, Brennan PJ, Dockrell HM; IDEAL Consortium..

Clin Vaccine Immunol. 2009 Mar;16(3):352-9. doi: 10.1128/CVI.00414-08.

2.

Immunogenicity of Mycobacterium leprae unique antigens in leprosy endemic populations in Asia and Africa.

Bobosha K, Van Der Ploeg-Van Schip JJ, Zewdie M, Sapkota BR, Hagge DA, Franken KL, Inbiale W, Aseffa A, Ottenhoff TH, Geluk A.

Lepr Rev. 2011 Dec;82(4):445-58.

PMID:
22439283
3.

Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection.

Geluk A, Klein MR, Franken KL, van Meijgaarden KE, Wieles B, Pereira KC, Bührer-Sékula S, Klatser PR, Brennan PJ, Spencer JS, Williams DL, Pessolani MC, Sampaio EP, Ottenhoff TH.

Infect Immun. 2005 Sep;73(9):5636-44.

4.

Rational combination of peptides derived from different Mycobacterium leprae proteins improves sensitivity for immunodiagnosis of M. leprae infection.

Geluk A, van der Ploeg J, Teles RO, Franken KL, Prins C, Drijfhout JW, Sarno EN, Sampaio EP, Ottenhoff TH.

Clin Vaccine Immunol. 2008 Mar;15(3):522-33. doi: 10.1128/CVI.00432-07.

5.

HLA and leprosy in the pre and postgenomic eras.

Geluk A, Ottenhoff TH.

Hum Immunol. 2006 Jun;67(6):439-45. Review.

PMID:
16728267
6.

A postgenomic approach to identification of Mycobacterium leprae-specific peptides as T-cell reagents.

Dockrell HM, Brahmbhatt S, Robertson BD, Britton S, Fruth U, Gebre N, Hunegnaw M, Hussain R, Manandhar R, Murillo L, Pessolani MC, Roche P, Salgado JL, Sampaio E, Shahid F, Thole JE, Young DB.

Infect Immun. 2000 Oct;68(10):5846-55.

7.

Enhancing sensitivity of detection of immune responses to Mycobacterium leprae peptides in whole-blood assays.

Geluk A, van der Ploeg-van Schip JJ, van Meijgaarden KE, Commandeur S, Drijfhout JW, Benckhuijsen WE, Franken KL, Naafs B, Ottenhoff TH.

Clin Vaccine Immunol. 2010 Jun;17(6):993-1004. doi: 10.1128/CVI.00046-10.

8.

Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy.

Spencer JS, Dockrell HM, Kim HJ, Marques MA, Williams DL, Martins MV, Martins ML, Lima MC, Sarno EN, Pereira GM, Matos H, Fonseca LS, Sampaio EP, Ottenhoff TH, Geluk A, Cho SN, Stoker NG, Cole ST, Brennan PJ, Pessolani MC.

J Immunol. 2005 Dec 15;175(12):7930-8.

9.

New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy.

Geluk A, Bobosha K, van der Ploeg-van Schip JJ, Spencer JS, Banu S, Martins MV, Cho SN, Franken KL, Kim HJ, Bekele Y, Uddin MK, Hadi SA, Aseffa A, Pessolani MC, Pereira GM, Dockrell HM, Ottenhoff TH.

J Immunol. 2012 May 15;188(10):4782-91. doi: 10.4049/jimmunol.1103452.

10.

Mycobacterium leprae virulence-associated peptides are indicators of exposure to M. leprae in Brazil, Ethiopia and Nepal.

Bobosha K, Tang ST, van der Ploeg-van Schip JJ, Bekele Y, Martins MV, Lund O, Franken KL, Khadge S, Pontes MA, Gonçalves Hde S, Hussien J, Thapa P, Kunwar CB, Hagge DA, Aseffa A, Pessolani MC, Pereira GM, Ottenhoff TH, Geluk A.

Mem Inst Oswaldo Cruz. 2012 Dec;107 Suppl 1:112-23.

11.

Immunologically reactive M. leprae antigens with relevance to diagnosis and vaccine development.

Sampaio LH, Stefani MM, Oliveira RM, Sousa AL, Ireton GC, Reed SG, Duthie MS.

BMC Infect Dis. 2011 Jan 26;11:26. doi: 10.1186/1471-2334-11-26.

12.

Presence of human T-cell responses to the Mycobacterium leprae 45-kilodalton antigen reflects infection with or exposure to M. leprae.

Macfarlane A, Mondragon-Gonzalez R, Vega-Lopez F, Wieles B, de Pena J, Rodriguez O, Suarez y de la Torre R, de Vries RR, Ottenhoff TH, Dockrell HM.

Clin Diagn Lab Immunol. 2001 May;8(3):604-11.

13.

Diagnostic assays for leprosy based on T-cell epitopes.

Dockrell HM, Brahmbhatt S, Robertson BD, Britton S, Fruth U, Gebre N, Hunegnaw M, Hussain R, Manadhar R, Murrillo L, Pessolani MC, Roche P, Salgado JL, Sampaio E, Shahid F, Thole JE, Young DB.

Lepr Rev. 2000 Dec;71 Suppl:S55-8; discussion S58-9.

PMID:
11201888
14.

Antigen-specific T-cell responses of leprosy patients.

Duthie MS, Goto W, Ireton GC, Reece ST, Sampaio LH, Grassi AB, Sousa AL, Martelli CM, Stefani MM, Reed SG.

Clin Vaccine Immunol. 2008 Nov;15(11):1659-65. doi: 10.1128/CVI.00234-08.

15.

Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy.

Martins MV, Guimarães MM, Spencer JS, Hacker MA, Costa LS, Carvalho FM, Geluk A, van der Ploeg-van Schip JJ, Pontes MA, Gonçalves HS, de Morais JP, Bandeira TJ, Pessolani MC, Brennan PJ, Pereira GM.

PLoS Negl Trop Dis. 2012;6(4):e1616. doi: 10.1371/journal.pntd.0001616.

16.

Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal.

Khadge S, Banu S, Bobosha K, van der Ploeg-van Schip JJ, Goulart IM, Thapa P, Kunwar CB, van Meijgaarden KE, van den Eeden SJ, Wilson L, Kabir S, Dey H, Goulart LR, Lobato J, Carvalho W, Bekele Y, Franken KL, Aseffa A, Spencer JS, Oskam L, Otttenhoff TH, Hagge DA, Geluk A.

BMC Infect Dis. 2015 Oct 28;15:477. doi: 10.1186/s12879-015-1128-0.

17.
18.

Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis.

Geluk A, van Meijgaarden KE, Franken KL, Subronto YW, Wieles B, Arend SM, Sampaio EP, de Boer T, Faber WR, Naafs B, Ottenhoff TH.

Infect Immun. 2002 May;70(5):2544-8.

19.

Analysis of T-cell and B-cell responses to recombinant M. leprae antigens in leprosy patients and in healthy contacts: significant T-cell responses to antigens in M. leprae nonresponders.

Thole JE, Janson AA, Kifle A, Howe RC, McLean K, Nurilygn A, Filley E, Shannon EJ, Bulla GJ, Hermans J, et al.

Int J Lepr Other Mycobact Dis. 1995 Sep;63(3):369-80.

PMID:
7594920
20.

Synergistic antigen combinations for the development of interferon gamma release assays for paucibacillary leprosy.

Oliveira RM, Hungria EM, de Araújo Freitas A, de Sousa AL, Costa MB, Reed SG, Duthie MS, Stefani MM.

Eur J Clin Microbiol Infect Dis. 2014 Aug;33(8):1415-24. doi: 10.1007/s10096-014-2077-z.

PMID:
24619112
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