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Items: 1 to 20 of 369


Elaboration, diversification and regulation of the Sir1 family of silencing proteins in Saccharomyces.

Gallagher JE, Babiarz JE, Teytelman L, Wolfe KH, Rine J.

Genetics. 2009 Apr;181(4):1477-91. doi: 10.1534/genetics.108.099663. Epub 2009 Jan 26.


Phylogenetic conservation and homology modeling help reveal a novel domain within the budding yeast heterochromatin protein Sir1.

Hou Z, Danzer JR, Mendoza L, Bose ME, Müller U, Williams B, Fox CA.

Mol Cell Biol. 2009 Feb;29(3):687-702. doi: 10.1128/MCB.00202-08. Epub 2008 Nov 24.


Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing.

Hou Z, Bernstein DA, Fox CA, Keck JL.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8489-94. Epub 2005 Jun 2.


Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain.

Connelly JJ, Yuan P, Hsu HC, Li Z, Xu RM, Sternglanz R.

Mol Cell Biol. 2006 Apr;26(8):3256-65.


Evolution and Functional Trajectory of Sir1 in Gene Silencing.

Ellahi A, Rine J.

Mol Cell Biol. 2016 Jan 25;36(7):1164-79. doi: 10.1128/MCB.01013-15.


The DNA end-binding protein Ku regulates silencing at the internal HML and HMR loci in Saccharomyces cerevisiae.

Vandre CL, Kamakaka RT, Rivier DH.

Genetics. 2008 Nov;180(3):1407-18. doi: 10.1534/genetics.108.094490. Epub 2008 Sep 14.


Design of a minimal silencer for the silent mating-type locus HML of Saccharomyces cerevisiae.

Weber JM, Ehrenhofer-Murray AE.

Nucleic Acids Res. 2010 Dec;38(22):7991-8000. doi: 10.1093/nar/gkq689. Epub 2010 Aug 10.


Functions of protosilencers in the formation and maintenance of heterochromatin in Saccharomyces cerevisiae.

Zhang X, Yu Q, Olsen L, Bi X.

PLoS One. 2012;7(5):e37092. doi: 10.1371/journal.pone.0037092. Epub 2012 May 17.


Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing.

Zhang Z, Hayashi MK, Merkel O, Stillman B, Xu RM.

EMBO J. 2002 Sep 2;21(17):4600-11.


The Ku complex in silencing the cryptic mating-type loci of Saccharomyces cerevisiae.

Patterson EE, Fox CA.

Genetics. 2008 Oct;180(2):771-83. doi: 10.1534/genetics.108.091710. Epub 2008 Aug 20.


Expanded roles of the origin recognition complex in the architecture and function of silenced chromatin in Saccharomyces cerevisiae.

Ozaydin B, Rine J.

Mol Cell Biol. 2010 Feb;30(3):626-39. doi: 10.1128/MCB.00614-09. Epub 2009 Nov 30.


Transcriptional silencing functions of the yeast protein Orc1/Sir3 subfunctionalized after gene duplication.

Hickman MA, Rusche LN.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19384-9. doi: 10.1073/pnas.1006436107. Epub 2010 Oct 25.


The origin recognition complex, SIR1, and the S phase requirement for silencing.

Fox CA, Ehrenhofer-Murray AE, Loo S, Rine J.

Science. 1997 Jun 6;276(5318):1547-51.


Epistatic interaction between the K-homology domain protein HEK2 and SIR1 at HMR and telomeres in yeast.

Denisenko O, Bomsztyk K.

J Mol Biol. 2008 Jan 25;375(4):1178-87. Epub 2007 Nov 12.


Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast.

Chien CT, Buck S, Sternglanz R, Shore D.

Cell. 1993 Nov 5;75(3):531-41.


Synthetic lethal screens identify gene silencing processes in yeast and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core.

van Welsem T, Frederiks F, Verzijlbergen KF, Faber AW, Nelson ZW, Egan DA, Gottschling DE, van Leeuwen F.

Mol Cell Biol. 2008 Jun;28(11):3861-72. doi: 10.1128/MCB.02050-07. Epub 2008 Apr 7.


Single-cell observations reveal intermediate transcriptional silencing states.

Xu EY, Zawadzki KA, Broach JR.

Mol Cell. 2006 Jul 21;23(2):219-29.


Synergy of repression and silencing gradients along the chromosome.

Ratna P, Scherrer S, Fleischli C, Becskei A.

J Mol Biol. 2009 Apr 10;387(4):826-39. doi: 10.1016/j.jmb.2009.02.025. Epub 2009 Feb 20.


Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly.

Onishi M, Liou GG, Buchberger JR, Walz T, Moazed D.

Mol Cell. 2007 Dec 28;28(6):1015-28.

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