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Items: 1 to 20 of 227

1.

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48. doi: 10.1101/gad.1752608.

2.

Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo.

Lee CS, Sund NJ, Vatamaniuk MZ, Matschinsky FM, Stoffers DA, Kaestner KH.

Diabetes. 2002 Aug;51(8):2546-51.

3.

Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice.

Ye DZ, Kaestner KH.

Gastroenterology. 2009 Dec;137(6):2052-62. doi: 10.1053/j.gastro.2009.08.059.

4.

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.

Lin W, Metzakopian E, Mavromatakis YE, Gao N, Balaskas N, Sasaki H, Briscoe J, Whitsett JA, Goulding M, Kaestner KH, Ang SL.

Dev Biol. 2009 Sep 15;333(2):386-96. doi: 10.1016/j.ydbio.2009.07.006.

5.

Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.

Ferri AL, Lin W, Mavromatakis YE, Wang JC, Sasaki H, Whitsett JA, Ang SL.

Development. 2007 Aug;134(15):2761-9.

6.
7.

Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.

Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL.

Development. 2015 Apr 1;142(7):1315-24. doi: 10.1242/dev.115808.

8.

Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates.

Wang A, Yue F, Li Y, Xie R, Harper T, Patel NA, Muth K, Palmer J, Qiu Y, Wang J, Lam DK, Raum JC, Stoffers DA, Ren B, Sander M.

Cell Stem Cell. 2015 Apr 2;16(4):386-99. doi: 10.1016/j.stem.2015.02.013.

9.

Foxa1 and Foxa2 regulate bile duct development in mice.

Li Z, White P, Tuteja G, Rubins N, Sackett S, Kaestner KH.

J Clin Invest. 2009 Jun;119(6):1537-45. doi: 10.1172/JCI38201.

10.

The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.

Boucher MJ, Simoneau M, Edlund H.

Endocrinology. 2009 Jan;150(1):87-97. doi: 10.1210/en.2007-0865.

PMID:
18772243
11.

Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.

van der Sluis M, Vincent A, Bouma J, Korteland-Van Male A, van Goudoever JB, Renes IB, Van Seuningen I.

Biochem Biophys Res Commun. 2008 May 16;369(4):1108-13. doi: 10.1016/j.bbrc.2008.02.158.

PMID:
18336786
12.

Winged-helix transcription factors and pancreatic development.

Lantz KA, Kaestner KH.

Clin Sci (Lond). 2005 Mar;108(3):195-204. Review.

PMID:
15631623
13.
14.

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.

Hoffman BG, Robertson G, Zavaglia B, Beach M, Cullum R, Lee S, Soukhatcheva G, Li L, Wederell ED, Thiessen N, Bilenky M, Cezard T, Tam A, Kamoh B, Birol I, Dai D, Zhao Y, Hirst M, Verchere CB, Helgason CD, Marra MA, Jones SJ, Hoodless PA.

Genome Res. 2010 Aug;20(8):1037-51. doi: 10.1101/gr.104356.109.

15.

Foxa2 regulates multiple pathways of insulin secretion.

Lantz KA, Vatamaniuk MZ, Brestelli JE, Friedman JR, Matschinsky FM, Kaestner KH.

J Clin Invest. 2004 Aug;114(4):512-20.

16.

In situ hybridization with 33P-labeled RNA probes for determination of cellular expression patterns of liver transcription factors in mouse embryos.

Rausa FM, Ye H, Lim L, Duncan SA, Costa RH.

Methods. 1998 Sep;16(1):29-41. Erratum in: Methods 1998 Nov;16(3):359-60.

PMID:
9774514
17.

The role of pdx1 and HNF6 in proliferation and differentiation of endocrine precursors.

Wilding L, Gannon M.

Diabetes Metab Res Rev. 2004 Mar-Apr;20(2):114-23. Review.

PMID:
15037986
18.

SIRT1 deacetylates FOXA2 and is critical for Pdx1 transcription and β-cell formation.

Wang RH, Xu X, Kim HS, Xiao Z, Deng CX.

Int J Biol Sci. 2013 Sep 21;9(9):934-46. doi: 10.7150/ijbs.7529.

19.

The Foxa family of transcription factors in development and metabolism.

Friedman JR, Kaestner KH.

Cell Mol Life Sci. 2006 Oct;63(19-20):2317-28. Review.

PMID:
16909212
20.

Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.

Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV.

Genes Dev. 2006 Jan 15;20(2):253-66.

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