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Endoplasmic reticulum stress plays a central role in development of leptin resistance.

Ozcan L, Ergin AS, Lu A, Chung J, Sarkar S, Nie D, Myers MG Jr, Ozcan U.

Cell Metab. 2009 Jan 7;9(1):35-51. doi: 10.1016/j.cmet.2008.12.004.


Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice.

Hakim F, Wang Y, Carreras A, Hirotsu C, Zhang J, Peris E, Gozal D.

Sleep. 2015 Jan 1;38(1):31-40. doi: 10.5665/sleep.4320.


Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress.

Kubota K, Niinuma Y, Kaneko M, Okuma Y, Sugai M, Omura T, Uesugi M, Uehara T, Hosoi T, Nomura Y.

J Neurochem. 2006 Jun;97(5):1259-68.


Endoplasmic reticulum stress induces leptin resistance.

Hosoi T, Sasaki M, Miyahara T, Hashimoto C, Matsuo S, Yoshii M, Ozawa K.

Mol Pharmacol. 2008 Dec;74(6):1610-9. doi: 10.1124/mol.108.050070.


Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats.

Mulhern ML, Madson CJ, Kador PF, Randazzo J, Shinohara T.

Mol Vis. 2007 Aug 10;13:1397-405.


Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis.

Seyhun E, Malo A, Schäfer C, Moskaluk CA, Hoffmann RT, Göke B, Kubisch CH.

Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G773-82. doi: 10.1152/ajpgi.00483.2010.


Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells.

Berger E, Haller D.

Biochem Biophys Res Commun. 2011 Jun 17;409(4):610-5. doi: 10.1016/j.bbrc.2011.05.043.


Three weeks voluntary running wheel exercise increases endoplasmic reticulum stress in the brain of mice.

Kim Y, Park M, Boghossian S, York DA.

Brain Res. 2010 Mar 4;1317:13-23. doi: 10.1016/j.brainres.2009.12.062.


Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance.

Rieusset J, Chauvin MA, Durand A, Bravard A, Laugerette F, Michalski MC, Vidal H.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):439-45. doi: 10.1016/j.bbrc.2011.11.135.


Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals.

Cai Z, Li F, Gong W, Liu W, Duan Q, Chen C, Ni L, Xia Y, Cianflone K, Dong N, Wang DW.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2345-54. doi: 10.1161/ATVBAHA.112.300226.


Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin.

Won JC, Jang PG, Namkoong C, Koh EH, Kim SK, Park JY, Lee KU, Kim MS.

Obesity (Silver Spring). 2009 Oct;17(10):1861-5. doi: 10.1038/oby.2009.194.


Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass.

Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G.

Cell. 2000 Jan 21;100(2):197-207.


Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice.

Amin A, Choi SK, Galan M, Kassan M, Partyka M, Kadowitz P, Henrion D, Trebak M, Belmadani S, Matrougui K.

J Pathol. 2012 Jun;227(2):165-74. doi: 10.1002/path.3960.


Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes.

Chen Y, Liu CP, Xu KF, Mao XD, Lu YB, Fang L, Yang JW, Liu C.

Am J Nephrol. 2008;28(6):1014-22. doi: 10.1159/000148209.


Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells.

Lee ES, Lee HJ, Lee YJ, Jeong JH, Kang S, Lim YB.

Biochem Biophys Res Commun. 2014 Jul 25;450(2):1005-9. doi: 10.1016/j.bbrc.2014.06.091.


GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007.


Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity.

Kim GW, Lin JE, Snook AE, Aing AS, Merlino DJ, Li P, Waldman SA.

Nutr Diabetes. 2016 May 23;6:e211. doi: 10.1038/nutd.2016.18.


Changes in the neuroendocrine control of energy homeostasis by adiposity signals during aging.

Carrascosa JM, Ros M, Andrés A, Fernández-Agulló T, Arribas C.

Exp Gerontol. 2009 Jan-Feb;44(1-2):20-5. doi: 10.1016/j.exger.2008.05.005. Review.


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