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Items: 1 to 20 of 71

1.

Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.

Wills-Karp M, Finkelman FD.

Sci Signal. 2008 Dec 23;1(51):pe55. doi: 10.1126/scisignal.1.51.pe55. Review.

2.

Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway.

Xiao H, Yin T, Wang XY, Uchida T, Chung J, White MF, Yang YC.

J Biol Chem. 2002 Mar 8;277(10):8091-8.

3.

The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction.

Wang LM, Michieli P, Lie WR, Liu F, Lee CC, Minty A, Sun XJ, Levine A, White MF, Pierce JH.

Blood. 1995 Dec 1;86(11):4218-27.

5.
6.

Interleukin-4 (IL-4) and IL-13 bind to a shared heterodimeric complex on endothelial cells mediating vascular cell adhesion molecule-1 induction in the absence of the common gamma chain.

Schnyder B, Lugli S, Feng N, Etter H, Lutz RA, Ryffel B, Sugamura K, Wunderli-Allenspach H, Moser R.

Blood. 1996 May 15;87(10):4286-95.

7.

Immune-mediated signaling in intestinal goblet cells via PI3-kinase- and AKT-dependent pathways.

Wang ML, Keilbaugh SA, Cash-Mason T, He XC, Li L, Wu GD.

Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G1122-30. doi: 10.1152/ajpgi.90430.2008.

8.
9.

IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells.

Lefort S, Vita N, Reeb R, Caput D, Ferrara P.

FEBS Lett. 1995 Jun 12;366(2-3):122-6.

10.

Interleukin-4 and interleukin-13 signaling connections maps.

Kelly-Welch AE, Hanson EM, Boothby MR, Keegan AD.

Science. 2003 Jun 6;300(5625):1527-8.

PMID:
12791978
11.
12.

Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.

Hartman ME, O'Connor JC, Godbout JP, Minor KD, Mazzocco VR, Freund GG.

J Biol Chem. 2004 Jul 2;279(27):28045-50.

13.

Tumor necrosis factor alpha enhances the expression of the interleukin (IL)-4 receptor alpha-chain on endothelial cells increasing IL-4 or IL-13-induced Stat6 activation.

Lugli SM, Feng N, Heim MH, Adam M, Schnyder B, Etter H, Yamage M, Eugster HP, Lutz RA, Zurawski G, Moser R.

J Biol Chem. 1997 Feb 28;272(9):5487-94.

14.

Signal transduction through the IL-4 and insulin receptor families.

Wang LM, Keegan A, Frankel M, Paul WE, Pierce JH.

Stem Cells. 1995 Jul;13(4):360-8. Review.

PMID:
7549895
15.

A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor.

Kraich M, Klein M, Patiño E, Harrer H, Nickel J, Sebald W, Mueller TD.

BMC Biol. 2006 Apr 26;4:13.

16.

Interleukin-4 and interleukin-13: their similarities and discrepancies.

Chomarat P, Banchereau J.

Int Rev Immunol. 1998;17(1-4):1-52. Review.

PMID:
9914942
17.
19.

The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

Sun XJ, Pons S, Wang LM, Zhang Y, Yenush L, Burks D, Myers MG Jr, Glasheen E, Copeland NG, Jenkins NA, Pierce JH, White MF.

Mol Endocrinol. 1997 Feb;11(2):251-62.

PMID:
9013772
20.

STAT-1 is activated by IL-4 and IL-13 in multiple cell types.

Wang IM, Lin H, Goldman SJ, Kobayashi M.

Mol Immunol. 2004 Jul;41(9):873-84.

PMID:
15261459
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