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Items: 1 to 20 of 116

1.

Expansion of the human mu-opioid receptor gene architecture: novel functional variants.

Shabalina SA, Zaykin DV, Gris P, Ogurtsov AY, Gauthier J, Shibata K, Tchivileva IE, Belfer I, Mishra B, Kiselycznyk C, Wallace MR, Staud R, Spiridonov NA, Max MB, Goldman D, Fillingim RB, Maixner W, Diatchenko L.

Hum Mol Genet. 2009 Mar 15;18(6):1037-51. doi: 10.1093/hmg/ddn439. Epub 2008 Dec 22.

2.

Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon.

Doyle GA, Sheng XR, Lin SS, Press DM, Grice DE, Buono RJ, Ferraro TN, Berrettini WH.

Gene. 2007 Jun 15;395(1-2):98-107. Epub 2007 Feb 20.

3.

A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions.

Xu J, Lu Z, Xu M, Pan L, Deng Y, Xie X, Liu H, Ding S, Hurd YL, Pasternak GW, Klein RJ, Cartegni L, Zhou W, Pan YX.

J Neurosci. 2014 Aug 13;34(33):11048-66. doi: 10.1523/JNEUROSCI.3986-13.2014.

4.

Identification of three mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon.

Doyle GA, Rebecca Sheng X, Lin SS, Press DM, Grice DE, Buono RJ, Ferraro TN, Berrettini WH.

Gene. 2007 Feb 15;388(1-2):135-47. Epub 2006 Nov 1.

PMID:
17156941
5.

Haplotype block structure of the genomic region of the mu opioid receptor gene.

Levran O, Awolesi O, Linzy S, Adelson M, Kreek MJ.

J Hum Genet. 2011 Feb;56(2):147-55. doi: 10.1038/jhg.2010.150. Epub 2010 Dec 16.

6.

Association of μ-opioid receptor gene (OPRM1) haplotypes with postoperative nausea and vomiting.

Sugino S, Hayase T, Higuchi M, Saito K, Moriya H, Kumeta Y, Kurosawa N, Namiki A, Janicki PK.

Exp Brain Res. 2014 Aug;232(8):2627-35. doi: 10.1007/s00221-014-3987-9. Epub 2014 May 24.

PMID:
24858579
7.

Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1.

Xu J, Xu M, Rossi GC, Pasternak GW, Pan YX.

Mol Pain. 2011 Jan 21;7:9. doi: 10.1186/1744-8069-7-9.

9.

Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids.

Diatchenko L, Robinson JE, Maixner W.

Eur J Pain Suppl. 2011 Nov 11;5(2):433-438.

10.

Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

Zhang Y, Wang D, Johnson AD, Papp AC, Sadée W.

J Biol Chem. 2005 Sep 23;280(38):32618-24. Epub 2005 Jul 26. Erratum in: J Biol Chem. 2005 Nov 18;280(46):38888.

11.

Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence.

Smith RJ, Doyle GA, Han AM, Crowley JJ, Oslin DW, Patkar AA, Mannelli P, Demaria PA Jr, O'brien CP, Berrettini WH.

Am J Med Genet B Neuropsychiatr Genet. 2005 Feb 5;133B(1):105-9.

PMID:
15558714
12.

The G allele of SNP E1/A118G at the mu-opioid receptor gene locus shows genomic evidence of recent positive selection.

Pang GS, Wang J, Wang Z, Goh C, Lee CG.

Pharmacogenomics. 2009 Jul;10(7):1101-9. doi: 10.2217/pgs.09.63.

PMID:
19604083
13.

Mu opioid receptor gene variants: lack of association with alcohol dependence.

Bergen AW, Kokoszka J, Peterson R, Long JC, Virkkunen M, Linnoila M, Goldman D.

Mol Psychiatry. 1997 Oct-Nov;2(6):490-4.

PMID:
9399694
14.

Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction.

Deb I, Chakraborty J, Gangopadhyay PK, Choudhury SR, Das S.

J Neurochem. 2010 Jan;112(2):486-96. doi: 10.1111/j.1471-4159.2009.06472.x. Epub 2009 Nov 4.

15.

Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107.

Lu Z, Xu J, Xu M, Pasternak GW, Pan YX.

Mol Pharmacol. 2014 Feb;85(2):368-80. doi: 10.1124/mol.113.089292. Epub 2013 Dec 3.

16.

Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin.

Shi J, Hui L, Xu Y, Wang F, Huang W, Hu G.

Hum Mutat. 2002 Apr;19(4):459-60.

PMID:
11933204
17.

Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery.

Fukuda K, Hayashida M, Ide S, Saita N, Kokita Y, Kasai S, Nishizawa D, Ogai Y, Hasegawa J, Nagashima M, Tagami M, Komatsu H, Sora I, Koga H, Kaneko Y, Ikeda K.

Pain. 2009 Dec 15;147(1-3):194-201. doi: 10.1016/j.pain.2009.09.004. Epub 2009 Sep 26.

PMID:
19783098
18.

Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans.

Luo X, Kranzler HR, Zhao H, Gelernter J.

Am J Med Genet B Neuropsychiatr Genet. 2003 Jul 1;120B(1):97-108.

PMID:
12815747
19.

A118g polymorphism in mu opioid receptor gene (oprm1): association with opiate addiction in subjects of Indian origin.

Kapur S, Sharad S, Singh RA, Gupta AK.

J Integr Neurosci. 2007 Dec;6(4):511-22.

PMID:
18181266
20.

Do genetic predictors of pain sensitivity associate with persistent widespread pain?

Holliday KL, Nicholl BI, Macfarlane GJ, Thomson W, Davies KA, McBeth J.

Mol Pain. 2009 Sep 23;5:56. doi: 10.1186/1744-8069-5-56.

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