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A line of mice selected for high blood ethanol concentrations shows drinking in the dark to intoxication.

Crabbe JC, Metten P, Rhodes JS, Yu CH, Brown LL, Phillips TJ, Finn DA.

Biol Psychiatry. 2009 Apr 15;65(8):662-70. doi: 10.1016/j.biopsych.2008.11.002. Epub 2008 Dec 18.


High drinking in the dark mice: a genetic model of drinking to intoxication.

Barkley-Levenson AM, Crabbe JC.

Alcohol. 2014 May;48(3):217-23. doi: 10.1016/j.alcohol.2013.10.007. Epub 2013 Nov 15. Review.


Selectively bred crossed high-alcohol-preferring mice drink to intoxication and develop functional tolerance, but not locomotor sensitization during free-choice ethanol access.

Matson LM, Kasten CR, Boehm SL 2nd, Grahame NJ.

Alcohol Clin Exp Res. 2014 Jan;38(1):267-74. doi: 10.1111/acer.12216. Epub 2013 Aug 1.


Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice.

Rhodes JS, Best K, Belknap JK, Finn DA, Crabbe JC.

Physiol Behav. 2005 Jan 31;84(1):53-63.


Alcohol preference drinking in a mouse line selectively bred for high drinking in the dark.

Crabbe JC, Spence SE, Brown LL, Metten P.

Alcohol. 2011 Aug;45(5):427-40. doi: 10.1016/j.alcohol.2010.12.001. Epub 2010 Dec 30.


Mouse inbred strain differences in ethanol drinking to intoxication.

Rhodes JS, Ford MM, Yu CH, Brown LL, Finn DA, Garland T Jr, Crabbe JC.

Genes Brain Behav. 2007 Feb;6(1):1-18.


Distinct ethanol drinking microstructures in two replicate lines of mice selected for drinking to intoxication.

Barkley-Levenson AM, Crabbe JC.

Genes Brain Behav. 2015 Jun;14(5):398-410. doi: 10.1111/gbb.12225. Erratum in: Genes Brain Behav. 2016 Mar;15(3):356.


Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice.

Mulligan MK, Rhodes JS, Crabbe JC, Mayfield RD, Harris RA, Ponomarev I.

Alcohol Clin Exp Res. 2011 Apr;35(4):659-70. doi: 10.1111/j.1530-0277.2010.01384.x. Epub 2011 Jan 11.


Genetic relationship between predisposition for binge alcohol consumption and blunted sensitivity to adverse effects of alcohol in mice.

Fritz BM, Cordero KA, Barkley-Levenson AM, Metten P, Crabbe JC, Boehm SL 2nd.

Alcohol Clin Exp Res. 2014 May;38(5):1284-92. doi: 10.1111/acer.12385. Epub 2014 Feb 25.


Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice.

Crabbe JC, Metten P, Belknap JK, Spence SE, Cameron AJ, Schlumbohm JP, Huang LC, Barkley-Levenson AM, Ford MM, Phillips TJ.

Genes Brain Behav. 2014 Feb;13(2):236-46. doi: 10.1111/gbb.12105. Epub 2013 Dec 6.


Pharmacologically relevant intake during chronic, free-choice drinking rhythms in selectively bred high alcohol-preferring mice.

Matson LM, Grahame NJ.

Addict Biol. 2013 Nov;18(6):921-9. doi: 10.1111/j.1369-1600.2011.00412.x. Epub 2011 Nov 29.


Ethanol drinking microstructure of a high drinking in the dark selected mouse line.

Barkley-Levenson AM, Crabbe JC.

Alcohol Clin Exp Res. 2012 Aug;36(8):1330-9. doi: 10.1111/j.1530-0277.2012.01749.x. Epub 2012 Apr 23.


Selection for high alcohol preference drinking in mice results in heightened sensitivity and rapid development of acute functional tolerance to alcohol's ataxic effects.

Fritz BM, Grahame NJ, Boehm SL 2nd.

Genes Brain Behav. 2013 Feb;12(1):78-86. doi: 10.1111/j.1601-183X.2012.00830.x. Epub 2012 Aug 31.


Neuropeptide Y response to alcohol is altered in nucleus accumbens of mice selectively bred for drinking to intoxication.

Barkley-Levenson AM, Ryabinin AE, Crabbe JC.

Behav Brain Res. 2016 Apr 1;302:160-70. doi: 10.1016/j.bbr.2016.01.015. Epub 2016 Jan 9.


Rewarding and aversive effects of ethanol in High Drinking in the Dark selectively bred mice.

Barkley-Levenson AM, Cunningham CL, Smitasin PJ, Crabbe JC.

Addict Biol. 2015 Jan;20(1):80-90. doi: 10.1111/adb.12079. Epub 2013 Jul 30.


Ataxia and c-Fos expression in mice drinking ethanol in a limited access session.

Sharpe AL, Tsivkovskaia NO, Ryabinin AE.

Alcohol Clin Exp Res. 2005 Aug;29(8):1419-26.


Chronic free-choice drinking in crossed high alcohol preferring mice leads to sustained blood ethanol levels and metabolic tolerance without evidence of liver damage.

Matson L, Liangpunsakul S, Crabb D, Buckingham A, Ross RA, Halcomb M, Grahame N.

Alcohol Clin Exp Res. 2013 Feb;37(2):194-201. doi: 10.1111/j.1530-0277.2012.01873.x. Epub 2012 Jul 3.


"Drinking in the dark" (DID) procedures: a model of binge-like ethanol drinking in non-dependent mice.

Thiele TE, Navarro M.

Alcohol. 2014 May;48(3):235-41. doi: 10.1016/j.alcohol.2013.08.005. Epub 2013 Oct 29. Review.


Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents.

McBride WJ, Li TK.

Crit Rev Neurobiol. 1998;12(4):339-69. Review.


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