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Items: 1 to 20 of 109

1.

Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase.

Chai SY, Yeatman HR, Parker MW, Ascher DB, Thompson PE, Mulvey HT, Albiston AL.

BMC Neurosci. 2008 Dec 3;9 Suppl 2:S14. doi: 10.1186/1471-2202-9-S2-S14. Review.

2.

Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers.

Albiston AL, Diwakarla S, Fernando RN, Mountford SJ, Yeatman HR, Morgan B, Pham V, Holien JK, Parker MW, Thompson PE, Chai SY.

Br J Pharmacol. 2011 Sep;164(1):37-47. doi: 10.1111/j.1476-5381.2011.01402.x. Review.

3.

The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus--potential role in modulation of glucose uptake in neurones?

Fernando RN, Albiston AL, Chai SY.

Eur J Neurosci. 2008 Aug;28(3):588-98. doi: 10.1111/j.1460-9568.2008.06347.x.

PMID:
18702730
4.

The angiotensin IV/AT4 receptor.

Chai SY, Fernando R, Peck G, Ye SY, Mendelsohn FA, Jenkins TA, Albiston AL.

Cell Mol Life Sci. 2004 Nov;61(21):2728-37. Review.

PMID:
15549174
5.

Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).

Lew RA, Mustafa T, Ye S, McDowall SG, Chai SY, Albiston AL.

J Neurochem. 2003 Jul;86(2):344-50.

6.

Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory.

Albiston AL, Fernando RN, Yeatman HR, Burns P, Ng L, Daswani D, Diwakarla S, Pham V, Chai SY.

Neurobiol Learn Mem. 2010 Jan;93(1):19-30. doi: 10.1016/j.nlm.2009.07.011.

PMID:
19660563
7.

Insulin-regulated aminopeptidase: analysis of peptide substrate and inhibitor binding to the catalytic domain.

Ye S, Chai SY, Lew RA, Albiston AL.

Biol Chem. 2007 Apr;388(4):399-403.

PMID:
17391061
8.

Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase.

Albiston AL, Morton CJ, Ng HL, Pham V, Yeatman HR, Ye S, Fernando RN, De Bundel D, Ascher DB, Mendelsohn FA, Parker MW, Chai SY.

FASEB J. 2008 Dec;22(12):4209-17. doi: 10.1096/fj.08-112227.

9.

Structure-activity study of LVV-hemorphin-7: angiotensin AT4 receptor ligand and inhibitor of insulin-regulated aminopeptidase.

Lee J, Mustafa T, McDowall SG, Mendelsohn FA, Brennan M, Lew RA, Albiston AL, Chai SY.

J Pharmacol Exp Ther. 2003 Apr;305(1):205-11.

10.

Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase.

Albiston AL, McDowall SG, Matsacos D, Sim P, Clune E, Mustafa T, Lee J, Mendelsohn FA, Simpson RJ, Connolly LM, Chai SY.

J Biol Chem. 2001 Dec 28;276(52):48623-6.

11.

Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.

Ascher DB, Cromer BA, Morton CJ, Volitakis I, Cherny RA, Albiston AL, Chai SY, Parker MW.

Biochemistry. 2011 Apr 5;50(13):2611-22. doi: 10.1021/bi101893w.

PMID:
21348480
12.

Angiotensin IV and LVV-haemorphin 7 enhance spatial working memory in rats: effects on hippocampal glucose levels and blood flow.

De Bundel D, Smolders I, Yang R, Albiston AL, Michotte Y, Chai SY.

Neurobiol Learn Mem. 2009 Jul;92(1):19-26. doi: 10.1016/j.nlm.2009.02.004.

PMID:
19233301
13.

Involvement of insulin-regulated aminopeptidase in the effects of the renin-angiotensin fragment angiotensin IV: a review.

Stragier B, De Bundel D, Sarre S, Smolders I, Vauquelin G, Dupont A, Michotte Y, Vanderheyden P.

Heart Fail Rev. 2008 Sep;13(3):321-37. Review.

PMID:
17990104
14.

Therapeutic targeting of insulin-regulated aminopeptidase: heads and tails?

Albiston AL, Peck GR, Yeatman HR, Fernando R, Ye S, Chai SY.

Pharmacol Ther. 2007 Dec;116(3):417-27. Review.

PMID:
17900701
15.

Targeting the insulin-regulated aminopeptidase/AT4 receptor for cognitive disorders.

Hallberg M.

Drug News Perspect. 2009 Apr;22(3):133-9. doi: 10.1358/dnp.2009.22.3.1325032. Review.

PMID:
19440555
16.

LVV-hemorphin 7 and angiotensin IV in correlation with antinociception and anti-thermal hyperalgesia in rats.

Cheng BC, Tao PL, Cheng YY, Huang EY.

Peptides. 2012 Jul;36(1):9-16. doi: 10.1016/j.peptides.2012.03.019.

PMID:
22484286
17.

Alzheimer's, angiotensin IV and an aminopeptidase.

Albiston AL, Fernando R, Ye S, Peck GR, Chai SY.

Biol Pharm Bull. 2004 Jun;27(6):765-7. Review.

18.

AT4 receptor is insulin-regulated membrane aminopeptidase: potential mechanisms of memory enhancement.

Albiston AL, Mustafa T, McDowall SG, Mendelsohn FA, Lee J, Chai SY.

Trends Endocrinol Metab. 2003 Mar;14(2):72-7. Review.

PMID:
12591177
19.

Sub-cellular localization of insulin-regulated membrane aminopeptidase, IRAP to vesicles in neurons.

Fernando RN, Luff SE, Albiston AL, Chai SY.

J Neurochem. 2007 Aug;102(3):967-76.

20.

Cyclic insulin-regulated aminopeptidase (IRAP)/AT4 receptor ligands.

Axén A, Lindeberg G, Demaegdt H, Vauquelin G, Karlén A, Hallberg M.

J Pept Sci. 2006 Nov;12(11):705-13.

PMID:
16967438
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