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Items: 1 to 20 of 132

1.

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.

Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y, Casadesus G, Zhu X.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19318-23. doi: 10.1073/pnas.0804871105. Epub 2008 Dec 2.

2.

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.

Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X.

J Neurosci. 2009 Jul 15;29(28):9090-103. doi: 10.1523/JNEUROSCI.1357-09.2009.

3.

Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction.

Wang X, Petrie TG, Liu Y, Liu J, Fujioka H, Zhu X.

J Neurochem. 2012 Jun;121(5):830-9. doi: 10.1111/j.1471-4159.2012.07734.x. Epub 2012 Apr 12.

4.

Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.

Kim DI, Lee KH, Gabr AA, Choi GE, Kim JS, Ko SH, Han HJ.

Biochim Biophys Acta. 2016 Nov;1863(11):2820-2834. doi: 10.1016/j.bbamcr.2016.09.003. Epub 2016 Sep 4.

5.
6.

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell.

Gan X, Huang S, Wu L, Wang Y, Hu G, Li G, Zhang H, Yu H, Swerdlow RH, Chen JX, Yan SS.

Biochim Biophys Acta. 2014 Feb;1842(2):220-31. doi: 10.1016/j.bbadis.2013.11.009. Epub 2013 Nov 16.

7.

Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

Manczak M, Kandimalla R, Fry D, Sesaki H, Reddy PH.

Hum Mol Genet. 2016 Dec 1;25(23):5148-5166. doi: 10.1093/hmg/ddw330.

PMID:
27677309
8.

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease.

Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X.

J Neurochem. 2012 Feb;120(3):419-29. doi: 10.1111/j.1471-4159.2011.07581.x. Epub 2011 Dec 8.

9.

Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins.

Wu S, Zhou F, Zhang Z, Xing D.

FEBS J. 2011 Apr;278(6):941-54. doi: 10.1111/j.1742-4658.2011.08010.x. Epub 2011 Feb 3.

10.

Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases.

Reddy PH, Reddy TP, Manczak M, Calkins MJ, Shirendeb U, Mao P.

Brain Res Rev. 2011 Jun 24;67(1-2):103-18. doi: 10.1016/j.brainresrev.2010.11.004. Epub 2010 Dec 8. Review.

12.

Neural stem cell transplantation enhances mitochondrial biogenesis in a transgenic mouse model of Alzheimer's disease-like pathology.

Zhang W, Gu GJ, Shen X, Zhang Q, Wang GM, Wang PJ.

Neurobiol Aging. 2015 Mar;36(3):1282-92. doi: 10.1016/j.neurobiolaging.2014.10.040. Epub 2014 Dec 18.

PMID:
25582749
13.

Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein.

Niu J, Yu M, Wang C, Xu Z.

J Neurochem. 2012 Aug;122(3):650-8. doi: 10.1111/j.1471-4159.2012.07809.x. Epub 2012 Jun 22.

14.

Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.

Zhang C, Shi Z, Zhang L, Zhou Z, Zheng X, Liu G, Bu G, Fraser PE, Xu H, Zhang YW.

J Cell Sci. 2016 Mar 1;129(5):994-1002. doi: 10.1242/jcs.176792. Epub 2016 Jan 26.

15.

Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation.

Rönnbäck A, Pavlov PF, Mansory M, Gonze P, Marlière N, Winblad B, Graff C, Behbahani H.

J Neurochem. 2016 Feb;136(3):497-502. doi: 10.1111/jnc.13410. Epub 2015 Nov 19.

16.

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.

Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.

EMBO J. 2008 Jan 23;27(2):433-46. doi: 10.1038/sj.emboj.7601963. Epub 2008 Jan 17.

17.

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.

Cho DH, Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, Lipton SA.

Science. 2009 Apr 3;324(5923):102-5. doi: 10.1126/science.1171091.

18.
19.

Extracellular signal-regulated kinase is involved in alpha-synuclein-induced mitochondrial dynamic disorders by regulating dynamin-like protein 1.

Gui YX, Wang XY, Kang WY, Zhang YJ, Zhang Y, Zhou Y, Quinn TJ, Liu J, Chen SD.

Neurobiol Aging. 2012 Dec;33(12):2841-54. doi: 10.1016/j.neurobiolaging.2012.02.001. Epub 2012 Mar 22.

PMID:
22445325
20.

TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression.

Takamura H, Koyama Y, Matsuzaki S, Yamada K, Hattori T, Miyata S, Takemoto K, Tohyama M, Katayama T.

PLoS One. 2012;7(12):e51912. doi: 10.1371/journal.pone.0051912. Epub 2012 Dec 20.

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