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Items: 1 to 20 of 122

1.

Insertion and deletion in a non-essential region of the nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome (PRRS) virus: effects on virulence and immunogenicity.

Kim DY, Kaiser TJ, Horlen K, Keith ML, Taylor LP, Jolie R, Calvert JG, Rowland RR.

Virus Genes. 2009 Feb;38(1):118-28. doi: 10.1007/s11262-008-0303-4. Epub 2008 Dec 2.

PMID:
19048364
2.

Stable expression of foreign gene in nonessential region of nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome virus: applications for marker vaccine design.

Xu YZ, Zhou YJ, Zhang SR, Jiang YF, Tong W, Yu H, Tong GZ.

Vet Microbiol. 2012 Sep 14;159(1-2):1-10. doi: 10.1016/j.vetmic.2012.03.015. Epub 2012 Mar 30.

PMID:
22513707
4.

Pathogenicity and genetic characteristics associated with cell adaptation of a virulent porcine reproductive and respiratory syndrome virus nsp2 DEL strain CA-2.

Lee SC, Choi HW, Nam E, Noh YH, Lee S, Lee YJ, Park GS, Shin JH, Yoon IJ, Kang SY, Lee C.

Vet Microbiol. 2016 Apr 15;186:174-88. doi: 10.1016/j.vetmic.2016.03.002. Epub 2016 Mar 5.

PMID:
27016772
5.

In vivo growth of porcine reproductive and respiratory syndrome virus engineered nsp2 deletion mutants.

Faaberg KS, Kehrli ME Jr, Lager KM, Guo B, Han J.

Virus Res. 2010 Dec;154(1-2):77-85. doi: 10.1016/j.virusres.2010.07.024. Epub 2010 Jul 29. Review.

PMID:
20673840
6.

The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence.

Zhou L, Zhang J, Zeng J, Yin S, Li Y, Zheng L, Guo X, Ge X, Yang H.

J Virol. 2009 May;83(10):5156-67. doi: 10.1128/JVI.02678-08. Epub 2009 Feb 25.

7.

Genomic analysis and pathogenic characteristics of Type 2 porcine reproductive and respiratory syndrome virus nsp2 deletion strains isolated in Korea.

Choi HW, Nam E, Lee YJ, Noh YH, Lee SC, Yoon IJ, Kim HS, Kang SY, Choi YK, Lee C.

Vet Microbiol. 2014 Jun 4;170(3-4):232-45. doi: 10.1016/j.vetmic.2014.02.027. Epub 2014 Mar 4.

PMID:
24646599
8.

Immunodominant epitopes in nsp2 of porcine reproductive and respiratory syndrome virus are dispensable for replication, but play an important role in modulation of the host immune response.

Chen Z, Zhou X, Lunney JK, Lawson S, Sun Z, Brown E, Christopher-Hennings J, Knudsen D, Nelson E, Fang Y.

J Gen Virol. 2010 Apr;91(Pt 4):1047-57. doi: 10.1099/vir.0.016212-0. Epub 2009 Nov 18.

PMID:
19923257
9.

Attenuation and immunogenicity of a live high pathogenic PRRSV vaccine candidate with a 32-amino acid deletion in the nsp2 protein.

Lu W, Sun B, Mo J, Zeng X, Zhang G, Wang L, Zhou Q, Zhu L, Li Z, Xie Q, Bi Y, Ma J.

J Immunol Res. 2014;2014:810523. doi: 10.1155/2014/810523. Epub 2014 Jun 9.

10.

Non-structural protein 2 of the porcine reproductive and respiratory syndrome (PRRS) virus: a crucial protein in viral pathogenesis, immunity and diagnosis.

Wang FX, Song N, Chen LZ, Cheng SP, Wu H, Wen YJ.

Res Vet Sci. 2013 Aug;95(1):1-7. doi: 10.1016/j.rvsc.2013.03.015. Epub 2013 Apr 13. Review.

PMID:
23591056
11.
12.

Cross-reactive antibody responses to nsp1 and nsp2 of Porcine reproductive and respiratory syndrome virus.

Johnson CR, Yu W, Murtaugh MP.

J Gen Virol. 2007 Apr;88(Pt 4):1184-95.

PMID:
17374762
13.
14.

Effect of amino acids residues 323-433 and 628-747 in Nsp2 of representative porcine reproductive and respiratory syndrome virus strains on inflammatory response in vitro.

Liu X, Bai J, Wang H, Fan B, Li Y, Jiang P.

Virus Res. 2015 Oct 2;208:13-21. doi: 10.1016/j.virusres.2015.05.016. Epub 2015 Jun 2.

PMID:
26043979
16.

Development of genetic markers in the non-structural protein 2 region of a US type 1 porcine reproductive and respiratory syndrome virus: implications for future recombinant marker vaccine development.

Fang Y, Christopher-Hennings J, Brown E, Liu H, Chen Z, Lawson SR, Breen R, Clement T, Gao X, Bao J, Knudsen D, Daly R, Nelson E.

J Gen Virol. 2008 Dec;89(Pt 12):3086-96. doi: 10.1099/vir.0.2008/003426-0.

PMID:
19008397
17.
18.

Recovery of viable porcine reproductive and respiratory syndrome virus from an infectious clone containing a partial deletion within the Nsp2-encoding region.

Ran ZG, Chen XY, Guo X, Ge XN, Yoon KJ, Yang HC.

Arch Virol. 2008;153(5):899-907. doi: 10.1007/s00705-008-0064-3. Epub 2008 Mar 21.

PMID:
18357408
19.

Porcine reproductive and respiratory syndrome virus nonstructural protein 2 contributes to NF-κB activation.

Fang Y, Fang L, Wang Y, Lei Y, Luo R, Wang D, Chen H, Xiao S.

Virol J. 2012 Apr 30;9:83. doi: 10.1186/1743-422X-9-83.

20.

Development of a porcine reproductive and respiratory syndrome virus differentiable (DIVA) strain through deletion of specific immunodominant epitopes.

de Lima M, Kwon B, Ansari IH, Pattnaik AK, Flores EF, Osorio FA.

Vaccine. 2008 Jul 4;26(29-30):3594-600. doi: 10.1016/j.vaccine.2008.04.078. Epub 2008 May 19.

PMID:
18538899

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