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Items: 1 to 20 of 126

1.

Focal adhesion kinase is important for fluid shear stress-induced mechanotransduction in osteoblasts.

Young SR, Gerard-O'Riley R, Kim JB, Pavalko FM.

J Bone Miner Res. 2009 Mar;24(3):411-24. doi: 10.1359/jbmr.081102. Erratum in: J Bone Miner Res. 2013 Nov;28(11):2431.

2.

Activation of NF-kappaB by fluid shear stress, but not TNF-alpha, requires focal adhesion kinase in osteoblasts.

Young SR, Gerard-O'Riley R, Harrington M, Pavalko FM.

Bone. 2010 Jul;47(1):74-82. doi: 10.1016/j.bone.2010.03.014. Epub 2010 Mar 27.

3.

Non-overlapping functions for Pyk2 and FAK in osteoblasts during fluid shear stress-induced mechanotransduction.

Young SR, Hum JM, Rodenberg E, Turner CH, Pavalko FM.

PLoS One. 2011 Jan 25;6(1):e16026. doi: 10.1371/journal.pone.0016026.

4.
5.

Focal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivo.

Castillo AB, Blundo JT, Chen JC, Lee KL, Yereddi NR, Jang E, Kumar S, Tang WJ, Zarrin S, Kim JB, Jacobs CR.

PLoS One. 2012;7(9):e43291. doi: 10.1371/journal.pone.0043291. Epub 2012 Sep 21.

6.

Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction.

Rangaswami H, Marathe N, Zhuang S, Chen Y, Yeh JC, Frangos JA, Boss GR, Pilz RB.

J Biol Chem. 2009 May 29;284(22):14796-808. doi: 10.1074/jbc.M806486200. Epub 2009 Mar 11.

8.

Mechanical loading by fluid shear stress enhances IGF-1 receptor signaling in osteoblasts in a PKCzeta-dependent manner.

Triplett JW, O'Riley R, Tekulve K, Norvell SM, Pavalko FM.

Mol Cell Biomech. 2007 Mar;4(1):13-25.

PMID:
17879768
9.

Focal adhesion kinase signaling pathway is involved in mechanotransduction in MG-63 cells.

Wang B, Du T, Wang Y, Yang C, Zhang S, Cao X.

Biochem Biophys Res Commun. 2011 Jul 8;410(3):671-6. doi: 10.1016/j.bbrc.2011.06.054. Epub 2011 Jun 12.

PMID:
21693107
10.

RhoA-mediated signaling in mechanotransduction of osteoblasts.

Hamamura K, Swarnkar G, Tanjung N, Cho E, Li J, Na S, Yokota H.

Connect Tissue Res. 2012;53(5):398-406. doi: 10.3109/03008207.2012.671398. Epub 2012 Apr 10.

PMID:
22420753
11.

Inhibition of FSS-induced actin cytoskeleton reorganization by silencing LIMK2 gene increases the mechanosensitivity of primary osteoblasts.

Yang Z, Tan S, Shen Y, Chen R, Wu C, Xu Y, Song Z, Fu Q.

Bone. 2015 May;74:182-90. doi: 10.1016/j.bone.2014.12.024. Epub 2014 Dec 27.

PMID:
25549868
12.
13.

Src and focal adhesion kinase mediate mechanical strain-induced proliferation and ERK1/2 phosphorylation in human H441 pulmonary epithelial cells.

Chaturvedi LS, Marsh HM, Basson MD.

Am J Physiol Cell Physiol. 2007 May;292(5):C1701-13. Epub 2007 Jan 10.

14.

Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts.

Liu D, Genetos DC, Shao Y, Geist DJ, Li J, Ke HZ, Turner CH, Duncan RL.

Bone. 2008 Apr;42(4):644-52. doi: 10.1016/j.bone.2007.09.058. Epub 2007 Oct 16.

15.

Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation.

Kido S, Kuriwaka-Kido R, Imamura T, Ito Y, Inoue D, Matsumoto T.

Bone. 2009 Dec;45(6):1125-32. doi: 10.1016/j.bone.2009.07.087. Epub 2009 Aug 7.

PMID:
19665600
16.

Protein kinase G and focal adhesion kinase converge on Src/Akt/β-catenin signaling module in osteoblast mechanotransduction.

Rangaswami H, Schwappacher R, Tran T, Chan GC, Zhuang S, Boss GR, Pilz RB.

J Biol Chem. 2012 Jun 15;287(25):21509-19. doi: 10.1074/jbc.M112.347245. Epub 2012 May 4.

17.

Nmp4/CIZ inhibits mechanically induced beta-catenin signaling activity in osteoblasts.

Yang Z, Bidwell JP, Young SR, Gerard-O'Riley R, Wang H, Pavalko FM.

J Cell Physiol. 2010 May;223(2):435-41. doi: 10.1002/jcp.22057.

18.

Fluid flow induces Rankl expression in primary murine calvarial osteoblasts.

Mehrotra M, Saegusa M, Wadhwa S, Voznesensky O, Peterson D, Pilbeam C.

J Cell Biochem. 2006 Aug 1;98(5):1271-83.

PMID:
16514640
19.

Repetitive deformation activates Src-independent FAK-dependent ERK motogenic signals in human Caco-2 intestinal epithelial cells.

Chaturvedi LS, Gayer CP, Marsh HM, Basson MD.

Am J Physiol Cell Physiol. 2008 Jun;294(6):C1350-61. doi: 10.1152/ajpcell.00027.2008. Epub 2008 Apr 9.

20.

Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways.

Marin TM, Clemente CF, Santos AM, Picardi PK, Pascoal VD, Lopes-Cendes I, Saad MJ, Franchini KG.

Circ Res. 2008 Oct 10;103(8):813-24. doi: 10.1161/CIRCRESAHA.108.179754. Epub 2008 Aug 28.

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